Angana Mukherjee

Angana Mukherjee is a Research Assistant Professor in the Department of Biological Sciences at the University of Notre Dame, within the College of Science. Her research is centered on the molecular and genetic basis of drug resistance in the malaria parasite Plasmodium falciparum, with a focus on antimalarial therapies such as artemisinin and piperaquine. She is based at the Galvin Life Science Center and has been in her current role since 2020.

• PhD: School of Life Sciences, Jawaharlal Nehru University, New Delhi, India (2007)
• Postdoctoral Research Fellow: Centre de Recherche en Infectiologie, Université Laval, Québec, Canada (2007–2012)
• Research Associate: Harvard T.H. Chan School of Public Health (2012–2015)
• Research Scientist: Université Laval (2015–2020)
• Visiting Scientist: Harvard T.H. Chan School of Public Health (2015–present)

Her research interests lie at the intersection of cellular and molecular parasitology, genetics, and infectious disease. She investigates how Plasmodium falciparum develops resistance to frontline antimalarial drugs, particularly through mechanisms independent of known markers like kelch13. Using tools such as CRISPR-Cas9, reverse genetics, and molecular phenotyping, she explores parasite lipid metabolism, redox systems, and hemoglobin trafficking pathways. Her work contributes to understanding the evolution of drug resistance and identifying new therapeutic targets.

The 15 most recent publications highlight a strong focus on drug resistance mechanisms in both malaria and leishmaniasis. Key themes include gene amplification, copy number variation, phosphoinositide signaling, and genetic cross studies. Her work spans model systems from Plasmodium to Leishmania, reflecting a broad expertise in protozoan parasites. Publications appear in high-impact journals such as mBio, Nature Communications, PLoS Biology, and EMBO Reports, demonstrating consistent contributions to infectious disease research.

Angana Mukherjee has not been publicly awarded specific scientific prizes or fellowships based on the provided text.

She has collaborated extensively with leading researchers in parasitology, including Dr. Dyann Wirth at Harvard and Dr. Marc Ouellette at Université Laval. While no formal grants are listed, her long-standing research positions and publication record suggest sustained funding support. She has not advised any named students in the provided materials. Her work is conducted in collaboration with research teams at Notre Dame, Harvard, and Université Laval, with a strong emphasis on molecular and genomic approaches to combat drug-resistant parasitic diseases.