André Fischer

Prof. Dr. André Fischer is a W3 Professor at the Department for Psychiatry and Psychotherapy, University Medical Center Göttingen, and serves as Speaker of the German Center for Neurodegenerative Diseases (DZNE) site Göttingen. His research focuses on epigenetic mechanisms underlying neurodegenerative diseases like Alzheimer's, combining patient and mouse models with molecular, genetic, and bioinformatic techniques.

Education & Career:

• 2003-2006: Postdoctoral Associate at Harvard Medical School and MIT's Picower Center
• 2007-2011: Independent Group Leader at ENI
• Since 2011: W3 Professor and DZNE Site Speaker

Research Interests: His work explores how gene-environment interactions via epigenetic processes (histone modification, DNA methylation, non-coding RNAs) contribute to neurodegenerative and psychiatric diseases. Key areas include memory formation, neuroprotective therapies, and molecular pathways governing cognitive decline.

Publications: His articles highlight breakthroughs in HDAC6 inhibition for Alzheimer's, microRNA-based dementia therapies, and epigenetic regulation of fear memory extinction. These studies underscore his lab's interdisciplinary approach to translational neuroscience.

Affiliations: Active in the Göttingen Graduate Center's programs on Molecular Biology, Neuroscience, and Computational Neuroscience. Collaborates across departments to advance neurodegenerative disease research.