Andrey Guillaume

Andrey Guillaume is an Associate Professor at the University of Geneva (UNIGE), specializing in chromatin structure, gene regulation, and developmental biology. His research explores the interplay between genomic architecture and transcriptional control during embryonic development, particularly in limb formation and congenital disorders.

Research Focus

• Chromatin topology and TAD boundaries
• Enhancer-promoter communication
• Structural genomic variants in developmental disease
• Limb and axial skeleton patterning
• Evolution of regulatory landscapes
• Transcriptional robustness

Publications

His recent work (2024–2025) investigates enhancer adoption by retrotransposons, Pitx1 locus topology in Liebenberg syndrome, and the role of gene deserts in pleiotropic gene regulation. Earlier studies include mechanistic insights into Hox gene collinearity and the effects of genomic deletions/insertions on chromatin folding.