Andrew T Crane

Andrew T Crane is an Assistant Professor at the University of Minnesota's School of Medicine, affiliated with the Transplant and Cellular Therapy Division of the Department of Medicine. His work bridges stem cell biology, gene editing, and neuroregenerative medicine.

• Institution: University of Minnesota
• Rank: Assistant Professor
• Division: Transplant and Cellular Therapy

Research Interests

Dr. Crane focuses on exosome-based therapies for stroke and traumatic brain injury (TBI), brain organoid engineering to model neurodegenerative diseases, and human-animal chimeras for organ regeneration. His CRISPR-mRNA platforms enable precise cell engineering for transplantation, while his blastocyst complementation studies explore interspecies organogenesis.

Scientific Contributions

• Co-investigator on exogenic organ transplantation projects (NIH-funded)
• Led 3D brain organoid research for chronic TBI and CTE
• Key publications on stem cell guidelines for human embryos and chimera research
• Collaborative work with Professor Andrew Grande on canine TBI models

Grants & Collaborations

Dr. Crane has secured grants from the NIH and Minnesota Office of Higher Education for projects involving immunosuppression-free transplantation and exosome therapy. Collaborations span neuroscience, stem cell research, and biomedical engineering.