معرفی
Professor Andrew Preston is a faculty member at the University of Bath within the Department of Life Sciences. His research spans bacterial pathogenesis, genomics, and vaccine development, focusing on the genus Bordetella.
- Key affiliations: Milner Centre for Evolution, Centre for Bioengineering & Biomedical Technologies (CBio)
- Collaborators: Dr. Eric Harvill (Penn State), Dr. Bob Ernst (U. Baltimore-Maryland), Dr. Caroline Colijn (Imperial College), and GSK Biologicals
Research emphasizes:
- Infection Biology: Structure-function analysis of Bordetella LPS (Band A trisaccharide, O polysaccharide)
- Metabolism: Genome-scale modeling of B. pertussis metabolism for vaccine production
- Evolution: Genomic analysis of Bordetella population structure and evolution
His work contributes to UN Sustainable Development Goals (SDG3: Good Health and Well-being) through infectious disease research. Projects include:
- Developing bacterial GWAS methods (Leverhulme Trust)
- Engineering lipid A for tailored vaccine immunogenicity (MRC)
- PERISCOPE: Correlates of pertussis protection (EU Horizon 2020)
- Evolution of vaccine-evasive B. pertussis strains (UK Health Security Agency)
۰مقاله منتشرشده
