معرفی
Dr. Andrew Doxey is an Assistant Professor in the Department of Biology at the University of Waterloo. His research focuses on microbial genomics, toxin biology, and pathogen-host interactions, with particular expertise in bioinformatics-driven discovery of novel bacterial toxins and metagenomic analysis of infectious disease systems. His work spans diverse areas including virology, proteomics, and environmental microbiology, often integrating high-throughput sequencing technologies with computational modeling.
Key research themes include the evolutionary origins of neurotoxins, functional characterization of microbial gene clusters, and development of bioinformatics tools for genomic analysis. His lab has made significant contributions to understanding Clostridium botulinum toxin evolution, metaproteomic profiling of human microbiota, and wastewater-based pathogen surveillance. He maintains active collaborations in virology, environmental microbiology, and computational biology.
Recent studies highlight his work on SARS-CoV-2 pathogenesis, including gene expression dynamics in respiratory infections and the impact of cannabis smoke on immune responses. He has pioneered methods for metatranscriptomic profiling of pediatric sinusitis and developed open-source lateral flow immunoassay techniques for biomarker detection.
No formal awards or grants are listed in the provided text, though his extensive publication record indicates sustained research activity. His research group's work is accessible via his personal lab website (http://doxey.uwaterloo.ca/), which details ongoing projects in microbial genomics and environmental surveillance applications.
