Andrew Carter

Andrew Carter is a Researcher at the University of Cambridge, focusing on the structural and mechanistic analysis of dynein, a critical molecular motor protein involved in cellular transport. His work explores dynein's role in organelle positioning, neurodegeneration, and viral infection, utilizing advanced techniques like X-ray crystallography and cryo-electron microscopy.

Research interests include:

• Understanding dynein-dynactin-cargo adaptor activation via JIP3 and LIS1
• Mechanisms of long-range axonal transport
• Structural dynamics of dynein complexes on microtubules
• Biogenesis of ciliary outer dynein arms

Key contributions span structural biology and cell biophysics, with a focus on human cytoplasmic dynein auto-inhibition and activation. His group integrates biophysical and cell biological methods with cutting-edge structural biology to address questions about motor protein regulation and pathogenic hijacking.