Andreas Linkermann

Professor Andreas Linkermann holds the Chair of Nephrology at Heidelberg University's Mannheim Medical Faculty and directs the Fifth Department of Medicine at Mannheim University Hospital. His work integrates clinical care, research, and teaching across nephrology, transplantation medicine, endocrinology, and pulmonology. Research focuses on regulated cell death mechanisms (ferroptosis, necroptosis) in kidney diseases, acute organ injury, and transplant preservation. Key contributions include elucidating gasdermin D's role in immunothrombosis and defining ferroptosis pathways in metabolic and cardiovascular disorders. He leads translational projects on biomarkers for normothermic organ perfusion and sex-based differences in acute kidney injury. As a clinical leader, he oversees multidisciplinary teams advancing precision medicine approaches in renal and metabolic diseases.

Research interests span cell death immunogenicity, STING signaling in inflammation, and therapeutic targeting of lipid peroxidation. His work bridges basic science and clinical applications, with recent emphasis on ferroptosis modulation in diabetes, ischemia-reperfusion injury, and cancer cell vulnerability. He collaborates with the Mannheim Medical Technology Campus and contributes to Baden-Württemberg's healthcare innovation initiatives.