معرفی
Dr. Ana Muñiz-García serves as a Postdoctoral Researcher at the Centre for Genomics and Child Health within the Blizard Institute, Faculty of Medicine and Dentistry at Queen Mary University of London. She joined Prof. Dean Nižetić's laboratory in 2022, leading research on Alzheimer's disease pathology progression and neuronal dysfunction in Down Syndrome using advanced 2D/3D human induced pluripotent stem cell (hiPSC) models.
Her academic foundation includes:
- BSc (Hons) in Biotechnology from Universidad de León (Spain), where she validated organotypic brain slice models for stroke studies under Prof. Arsenio Fernández-López
- PhD from the University of Liverpool (UK), investigating extracellular vesicle release mechanisms in hypoxia and therapeutic applications of human umbilical cord-derived mesenchymal stromal cell vesicles with Dr. Silvia Mora and Prof. Patricia Murray
Her research integrates stem cell biology, neurogenetics, and molecular neuroscience to unravel pathological mechanisms in Down Syndrome-associated Alzheimer's disease. She pioneers hiPSC-derived neural models to identify early neurodegenerative markers and potential therapeutic targets, bridging developmental biology with neurodegenerative disease research.
Publication trends reveal expertise in extracellular vesicle therapeutics, hypoxia response pathways, and advanced cellular imaging techniques. Her work spans regenerative medicine applications, vascular biology, and neurodevelopmental disorder modeling, demonstrating consistent methodological innovation across nanotechnology, cell signaling, and disease modeling domains.
Within the Centre for Genomics and Child Health, she actively collaborates on interdisciplinary projects examining genetic determinants of neurodevelopmental disorders, contributing to Queen Mary's strategic focus on translational child health research through stem cell-based disease modeling and therapeutic discovery initiatives.
