Amanda C. LaRue

Amanda C. LaRue is a Professor in the Department of Pathology and Laboratory Medicine at the Medical University of South Carolina (MUSC). Her research focuses on stem cell biology, particularly hematopoietic stem cell plasticity and their roles in tissue regeneration and disease. She investigates how these cells contribute to fibrosis, cancer microenvironments, and bone repair.

Her work spans multiple disciplines including regenerative medicine, cancer biology, and orthopedics. Key contributions include studies on hematopoietic stem cells' ability to differentiate into non-hematopoietic tissues like osteoblasts and adipocytes, as well as their roles in tumor progression and fibrotic diseases.

Recent articles highlight her exploration of stress-related impacts on bone health, immunomodulatory pathways in fibrosis, and the therapeutic potential of stem cells in osteogenesis imperfecta. She collaborates on translational projects involving bone regeneration techniques and the molecular mechanisms underlying cellular differentiation.

• Key Technologies: Stem cell culture, animal models of disease, molecular biology assays
• Lab Focus: Tumor microenvironment dynamics, cellular reprogramming, bone repair mechanisms