Alice Lebreton

Alice Lebreton is a Researcher at the Biology Department of École Normale Supérieure (ENS), leading the BIRD team. Her research focuses on the molecular dialogue between Listeria monocytogenes and host epithelial cells, investigating bacterial invasion mechanisms and host response dynamics. She employs interdisciplinary approaches combining molecular biology, functional genomics, and cellular microbiology to study gene expression adaptations during infection.

Her team explores two primary research axes: (1) spatiotemporal regulation of host gene expression via post-transcriptional mechanisms and (2) intracellular bacterial niche establishment and its impact on infection outcomes. Techniques such as real-time microscopy and genomic analysis are central to her work.

Collaborations include studies on bacterial effector proteins, stress response pathways, and viral strain epidemiology. While no formal student advisees are listed, her publications reflect active contributions to microbiology and immunology. The BIRD team’s findings aim to uncover novel virulence factors and host defense strategies, with broader implications for infection biology.