معرفی
Dr. Alfonso Urbanucci is a Senior Research Fellow at the Tampere Institute for Advanced Study and Group Leader at the Faculty of Medicine and Health Technology, Tampere University, Finland. He is also Project Group Leader at the Institute for Cancer Research, Oslo University Hospital, Norway, and Associate Investigator at the Norwegian Centre for Molecular Medicine (NCMM)-EMBL partnership. His research spans prostate cancer biology, chromatin dynamics, gene regulation, and precision medicine, with a focus on single-cell analysis and tumor microenvironment.
- PhD in Cancer Genetics and Molecular Biology of Cancer, University of Tampere (2012)
- Biology with specialization in Pathophysiology, University of Perugia, Italy
Dr. Urbanucci's research focuses on the transcriptional and chromatin drivers of prostate cancer progression, particularly centered on the androgen receptor. His lab investigates bromodomain inhibitors, epigenetic mechanisms of drug resistance, and develops RNA-based tools for patient stratification. The group employs single-cell and spatial transcriptomics to dissect tumor heterogeneity and identify prognostic signatures. They also explore radiosensitizers and the impact of post-androgen signaling inhibition.
His recent publications reflect a strong trend in epigenetics, chromatin accessibility, tumor microenvironment interactions, and precision oncology. Key themes include endocrine resistance in metastatic prostate cancer, club-like cell immunosuppression, and signaling pathways in ovarian cancer chemoresistance. His work bridges computational and experimental oncology to develop clinically relevant biomarkers.
Dr. Urbanucci leads a dual-site research group in Oslo and Tampere, supported by grants such as those from the Norwegian Cancer Society. He mentors students and collaborates internationally, particularly through the Prostate Cancer Research Centre and EMBL partnerships.
- Principal Investigator, Urbanucci Lab (Oslo and Tampere)
- Project Group Leader, Institute for Cancer Research, Oslo University Hospital
- Group Leader, Prostate Cancer Research Centre (PCRC), Tampere University
