معرفی
Alexander Skorput serves as Assistant Professor in both the Department of Neurology and Department of Molecular and Systems Biology at Dartmouth College's Geisel School of Medicine. His research focuses on neuro-immune interactions within the somatosensory system, specifically investigating how immune responses alter neural pain circuits to drive chronic pain development.
Dr. Skorput's research interests center on environmental influences on nervous and immune system maturation, with emphasis on somatosensory processing and pathogen-induced immunological alterations. His lab employs behavioral, histological, electrophysiological, and imaging techniques across in vivo, ex vivo, and in vitro models to develop non-opioid analgesics targeting chronic pain pathophysiology. The lab actively investigates
- Neuro-immune circuit interactions
- Transition mechanisms from acute to chronic pain
- Developmental neurophysiology
- Novel immunomodulatory therapeutics
Analysis of recent publications reveals strong focus on T cell neuroimmunology and pain pathway modulation, with increasing emphasis on brain-resident memory T cells and viral vector approaches for somatosensory system targeting since 2022.
Dr. Skorput provides academic mentorship in a supportive lab environment focused on training next-generation neuro-immunologists. His lab officially opened in January 2023 (Borwell 744E) and actively recruits graduate students and postdocs through the IND program.
The Skorput Lab maintains collaborative relationships with other research groups including the Rosato Lab, with joint projects on neuro-immune interactions in ocular chronic pain. The lab operates within Dartmouth's neuroscience infrastructure including access to the Borwell building facilities.
