Alexander N. Fedenko

Alexander N. Fedenko, MD, is an Associate Professor of Clinical Pathology at the University of Southern California. His research focuses on sarcomas, particularly soft tissue and visceral sarcomas, alongside oncology and immunotherapy. He contributes to ESMO clinical practice guidelines and leads clinical trials evaluating novel therapies like immunocytokines and targeted drug combinations.

• Expertise: Sarcoma treatment protocols, immunotherapy, clinical trial design
• Affiliations: USC Keck School of Medicine (implied), World Sarcoma Network

Research emphasizes rare tumors like epithelioid sarcoma and alveolar soft part sarcoma, with studies on pazopanib, olaratumab, and trabectedin efficacy. Collaborates internationally on multidisciplinary sarcoma care and publishes extensively in oncology journals.

Recent work includes 2025 Phase Ib trials combining simlukafusp alfa with pembrolizumab for melanoma, and 2022 studies on PALB2 mutation-driven pancreatic adenocarcinoma treatment. His articles span 1985-2025, with a focus on therapeutic advancements and diagnostic pathology improvements.