معرفی
Dr Alexander Darlington is an Assistant Professor in Control and Engineering Biology at the University of Warwick's School of Engineering, and a Royal Academy of Engineering Research Fellow. His research focuses on advancing synthetic biology and microbial biotechnology through quantitative mathematical modeling to optimize industrial bioprocesses. He leads a multidisciplinary group developing frameworks to predict and control metabolic, gene expression, and growth dynamics in engineered microbes.
Education: MSci Natural Sciences (University of Cambridge, 2015), PhD Engineering (University of Warwick, 2018). Previous roles include a BBSRC Innovation Fellowship with Ingenza Ltd and postdoctoral research at Warwick under Prof. Declan Bates.
Research Interests: Combining systems biology, control engineering, and mathematical modeling to address bottlenecks in microbial cell factories. Key areas include:
- Predicting host-pathway interactions to improve strain design
- Dynamic resource allocation strategies for growth/production trade-offs
- Control systems for autonomous biomanufacturing
Recent Work: Published in Nature Communications (2025) and Journal of the Royal Society Interface (2025). Active in conferences like CDC2024 and SynBYSS, with collaborations across academia and industry (e.g., Ingenza Ltd).
Grants & Awards:
- Royal Academy of Engineering Research Fellowship (2021-)
- BBSRC Innovation Fellowship (2020)
- UKRI Engineering Biology Mission Award (2024)
Teaching: Leads modules including Computational Systems and Synthetic Biology (ES97J) and supervises BEng/MSc/PhD projects. Committed to widening participation through initiatives like Warwick iGEM and undergraduate research placements.
Labs/Teams: Directs the Darlington Group at Warwick, collaborating with experimental and computational biologists to validate models in vivo. Hosts PhD students and postdocs working on control strategies for metabolic pathways and genetic circuits.
