Alex Duval

Alex Duval is a Research Professor at Sorbonne University's Faculty of Medicine, leading the Microsatellite Instability and Cancers research team at Saint-Antoine Hospital's Research Centre. His work focuses on DNA mismatch repair-deficient tumors and microsatellite instability across multiple cancer types.

Dr. Duval's research interests span Cancer Genetics, Molecular Oncology, and Personalized Medicine, with particular expertise in DNA Mismatch Repair mechanisms and Microsatellite Instability phenomena. His laboratory investigates the pathophysiological aspects of MSI carcinogenesis through innovative approaches combining molecular biology, genomics, and translational research.

Analysis of Dr. Duval's recent publications reveals a strong emphasis on cancer diagnostics, particularly regarding microsatellite instability detection methods and their clinical applications. His work spans multiple cancer types including colorectal, pancreatic, and gliomas, with increasing focus on immunotherapy response prediction and precision medicine applications. The publications demonstrate an evolution from basic molecular mechanisms toward clinical translation, with growing emphasis on diagnostic standards and therapeutic implications.

Dr. Duval actively mentors doctoral students including Amélia Favier, Cody Feys, Erell Guillerm, and Alexandre Perrier. His research program has generated numerous collaborative projects with clinical researchers across Saint-Antoine Hospital, with funding supporting the development of unique biological tools, mouse models, and clinical databases.

The researcher leads a comprehensive laboratory investigating MSI tumors, having built specialized collections of biological samples and developed novel techniques for MSI cancer analysis. His team's translational approach has yielded discoveries in risk factors, biomarkers, and diagnostic tools with direct clinical relevance for patients suffering from MSI cancers.