Alessandra L. Moore

Alessandra L. Moore, M.D., serves as Assistant Professor in the Department of Surgery and joint appointment in the Department of Medicine at the University of Rochester Medical Center. As a surgical oncologist specializing in endocrine surgery, she provides advanced care for thyroid, parathyroid, and adrenal conditions across adult and pediatric populations, with clinical expertise in thyroidectomy, neck dissection, laparoscopic adrenalectomy, and minimally invasive parathyroid procedures.

Her educational journey includes:

• Bachelor of Science with honors from Hobart and William Smith Colleges
• M.D. from University of Massachusetts Medical School (Clinical and Translational Research Pathway)
• General Surgery Residency at Brigham and Women's Hospital
• Endocrine Surgery Fellowship at Harvard Combined Endocrine Surgery Program
• Postdoctoral research at Stanford University on scarless wound healing

Dr. Moore's research bridges clinical endocrine surgery with regenerative medicine, focusing on adrenal gland regeneration, wound healing mechanisms, DLK1+ progenitor cell aging, and novel treatments for pheochromocytoma/paraganglioma. Her lab maintains an endocrine tumor biorepository to accelerate translational discoveries while investigating pediatric endocrine disease therapies and patient-reported outcomes in parathyroid surgery.

Analysis of her 24 publications (2018-2023) reveals two dominant research streams: clinical outcomes in thyroid/parathyroid/adrenal surgery (2021-2023) and fundamental fibroblast biology in wound regeneration (2018-2021). This dual focus exemplifies her surgeon-scientist approach to improving cancer care through regenerative techniques and evidence-based surgical innovation.

Her scientific recognition includes:

• URMC PROActive Award (2024-2025)
• John A. Mannick MD Research Award (2018)
• Stanford Plastic Surgery Research Day Award (2018)
• Wound Healing Foundation Fellowship
• National Institutes of Health Pediatric Loan Repayment Program

Leading The Moore Lab, Dr. Moore directs projects spanning adrenal regeneration, hypoparathyroidism treatments, and living adrenal cancer models. Her patient-centered philosophy emphasizes evidence-based individualized care, reflected in publications addressing mentorship for expectant residents and surgical decision-making. She actively contributes to clinical trials and maintains a tissue biorepository to advance endocrine disease understanding.