معرفی
Alan K Fotoohi is a Researcher affiliated with the Department of Laboratory Medicine at Karolinska Institutet in Stockholm, Sweden, holding a position from 2023 to 2026. He earned his PhD from the Department of Oncology-Pathology at Karolinska Institutet in 2007.
His educational background includes:
- Doctor of Philosophy, Department of Oncology-Pathology, Karolinska Institutet, 2007
Fotoohi's research spans Cancer and Oncology, Clinical Laboratory Medicine, and Pharmacology and Toxicology. His work focuses on pharmacogenetics, drug metabolism, and chemotherapy, particularly investigating genetic polymorphisms that influence drug response and toxicity in cancer patients. He has developed and validated laboratory methods for drug monitoring and has conducted population studies in diverse ethnic groups, including Ethiopian and Kurdish populations.
Analysis of his 15 most recent publications (2004-2022) reveals a strong emphasis on personalized medicine in oncology. His studies frequently examine the impact of genetic variants (e.g., in DPYD, CYP2D6, CYP2J2, and thiopurine methyltransferase) on the pharmacokinetics and pharmacodynamics of chemotherapeutic agents such as tamoxifen, cyclophosphamide, and thiopurines. This research has contributed to understanding interindividual variability in drug response and optimizing dosing strategies.
