معرفی
Adrianus (Ando) Van Der Velden is an Associate Professor in the Department of Microbiology and Immunology at Stony Brook University. He is affiliated with the Center for Infectious Diseases and maintains an active research laboratory focused on host-pathogen interactions, particularly with Salmonella. His work integrates immunology, microbiology, and host defense mechanisms to understand infectious disease processes.
- Department of Microbiology and Immunology, Stony Brook University
- Center for Infectious Diseases
- 240 Centers for Molecular Medicine, Stony Brook, NY
Dr. Van Der Velden earned his Ph.D. in Molecular Microbiology and Immunology from Oregon Health and Science University in 2000. He completed postdoctoral training with Dr. Michael Starnbach at Harvard Medical School before joining Stony Brook University as an Assistant Professor (tenure-track) in 2008. He was promoted to Associate Professor with tenure in 2015.
Dr. Van Der Velden's research primarily focuses on host interactions with Salmonella, with emphasis on immunological aspects of infection. His laboratory investigates two major thematic areas: the role of inflammatory monocytes in immunity and host defense against Salmonella, and the mechanisms by which Salmonella inhibits T cell responses. His work has revealed how Salmonella exploits inflammatory monocytes to promote its expansion in the inflamed intestine through nitrate-dependent mechanisms, and how bacterial asparagine hydrolase inhibits T cell responses by causing asparagine deprivation. His research provides critical insights into the complex interplay between pathogens, host immune responses, and gut microbiota.
Analysis of Dr. Van Der Velden's recent publications reveals a consistent focus on Salmonella pathogenesis and host immune responses, with particular emphasis on monocyte function, T cell suppression mechanisms, and nutritional immunity. His work spans from basic molecular mechanisms of bacterial virulence to translational aspects of infection control. Recent publications increasingly incorporate broader immunological concepts, including connections to cancer immunology and mucosal immunity. The research demonstrates sophisticated integration of in vivo infection models with detailed cellular and molecular immunological approaches.
Dr. Van Der Velden actively mentors graduate students and has hosted rotation students in his laboratory. While specific grant information isn't detailed in the provided text, his sustained research output suggests successful grant funding from agencies supporting infectious disease and immunology research. His laboratory appears to maintain collaborations across multiple institutions, as evidenced by co-authorship patterns in his publications.
The Van Der Velden laboratory is situated within Stony Brook University's research infrastructure, with facilities in the Centers for Molecular Medicine. His work appears to integrate with Stony Brook's broader infectious disease research community through the Center for Infectious Diseases. The laboratory maintains active research programs investigating host-pathogen interactions using sophisticated murine infection models and advanced immunological techniques.
