معرفی
Adam Bates is a Postdoctoral Scientist at the University of Oxford's Dong Group, focusing on T cell responses against viruses and cancer. Affiliated with Hertford College, his research investigates CD8+ T cell dynamics in non-small-cell lung cancer (NSCLC) through single-cell RNA sequencing, spatial transcriptomics, and functional assays. He explores tumor-reactive T cell populations lacking PD-1 or targeting Cancer Testis Antigens to uncover mechanisms for improved immunotherapies.
His work addresses tumor microenvironment heterogeneity and aims to develop novel T cell-based therapeutics for patients resistant to PD-1 blockade. Recent publications highlight his expertise in characterizing T cell exhaustion states and viral memory responses, with a 2025 thesis on NSCLC T cell analysis and a 2019 review on antibody fragments.
Key collaborations include studies on MPXV immunity published in Nature Communications (2025), emphasizing T cell migratory potential and epitope mapping. His methodological focus spans scRNAseq, TCR sequencing, and in vitro functional validation.
