معرفی
Prof. Achillefs Kapanidis is a Professor of Biological Physics at the University of Oxford, currently affiliated with the Oxford Kavli Institute for Nanoscience Discovery and Condensed Matter Physics. He leads the 'Gene Machines' group, focusing on single-molecule studies of microbial gene expression, DNA repair, and AI-driven diagnostics.
- Education: BSc in Chemistry (Aristotelian University of Thessaloniki), MSc in Food Science (Rutgers), PhD in Biological Chemistry (Rutgers Waksman Institute)
Research Interests: The group investigates biological machinery in gene transcription and DNA repair using single-molecule fluorescence microscopy and AI. Key areas include:
- Single-molecule biophysics of transcription factors
- Antibiotic resistance detection via rapid diagnostics
- Miniaturized imaging technologies for pathogen identification
- Deep learning applications in cellular phenotyping
- Super-resolution microscopy development
- Living-cell molecular tracking
Publications Trends: Recent work emphasizes AI integration with single-molecule techniques for real-time pathogen analysis, spanning influenza, coronaviruses, and E. coli. Innovations include photobleaching-resistant imaging, microfluidic diagnostics, and spatial organization studies of transcription machinery.
Awards:
- 2019 Innovator of the Year Award (BBSRC) for Oxford Nanoimaging spin-out
Labs & Collaborations: The team moved to the Oxford Kavli Institute in 2021, collaborating with interdisciplinary DTC programs. Current projects include biosensor development and viral detection platforms.
