Accalia Mai-Wan Fu

Dr. Accalia Mai-Wan Fu is an Assistant Professor in the Program in Molecular Medicine at the University of Massachusetts Chan Medical School. She is also affiliated with multiple graduate programs, including the Morningside Graduate School of Biomedical Sciences in departments such as Biochemistry and Molecular Biotechnology, Cancer Biology, and Translational Science.

Her research focuses on the intersection of pancreatic beta cell biology, glucose metabolism, and metabolic diseases like diabetes. Key themes include mitochondrial bioenergetics, oxidative stress regulation, and signaling pathways involving LKB1, AMPK, and CREB coactivators. Recent work explores TFEB activation in inflammation and CRISPR-engineered adipocytes for metabolic syndrome therapy.

Selected publications highlight her contributions to understanding beta cell compensation, urea cycle partitioning, and environmental toxicants impacting diabetes progression. These studies span Cell Biology, Metabolism, and Biochemistry, with translational applications in Molecular Medicine and Therapeutic Development.

Dr. Fu leads the Fu Lab, which investigates mechanisms linking metabolic stress to beta cell dysfunction and develops genomic tools for diabetes research. She collaborates with researchers like Javier Irazoqui and Milena Bogunovic, and her work is disseminated across institutions via the Morningside Graduate School of Biomedical Sciences programs.