Aaron Varghese

Aaron Varghese, M.D. serves as an Assistant Professor in the Department of Obstetrics and Gynecology at the University of Rochester School of Medicine and Dentistry, where he specializes in gynecologic oncology through the University of Rochester Medical Faculty Group (URMFG). As a core member of the Gynecologic Oncology service, he provides multidisciplinary care for women with gynecologic cancers while advancing research and medical education.

His clinical training pathway includes:

• Medical Doctorate (MD) from Texas A&M University College of Medicine (2014)
• Obstetrics & Gynecology Residency at University of Missouri School of Medicine-Kansas City (2014-2018)
• Research Fellowship at Johns Hopkins University School of Medicine (2018-2020)
• Gynecologic Oncology Fellowship at Roswell Park Comprehensive Cancer Center (2020-2023)

Dr. Varghese's research program focuses on translational gynecologic oncology, with particular emphasis on ovarian cancer immunotherapy mechanisms, surgical innovations for complex patient populations, and rare tumor biology. His work on tertiary lymphoid structures explores novel immunotherapeutic opportunities, while surgical studies address critical gaps in care for morbidly obese cancer patients. He maintains active investigation into peritoneal disease processes and rare gynecologic malignancies through multi-institutional collaborations.

Analysis of his 12 publications (2017-2025) reveals a strong trajectory in immunotherapy biomarker discovery, surgical technique optimization, and rare disease characterization. His work consistently bridges laboratory insights with clinical applications, particularly in ovarian cancer microenvironment research and surgical access innovation. Recent high-impact studies in JAMA Oncology and Frontiers in Immunology demonstrate his growing influence in national cancer research.

As an educator, Dr. Varghese actively trains medical students, residents, and fellows in gynecologic oncology principles and surgical techniques. He participates in clinical trials investigating novel therapeutic approaches and contributes to professional guidelines through his scholarly work. His practice at Lattimore Medical Center integrates cutting-edge research with compassionate, patient-centered cancer care for the Rochester community.