معرفی
Dr. Aakash Basu is an Assistant Professor of Biochemistry and Royal Society University Research Fellow at Durham University's Department of Biosciences. He holds a PhD in Applied Physics from Stanford University (2013) and has conducted postdoctoral research at The Rockefeller University, Johns Hopkins University School of Medicine, and the University of Illinois. His research focuses on genomic methods development, DNA structure/mechanics, and protein-DNA interactions using high-throughput assays and single-molecule biophysics.
Key research interests include understanding the 'mechanical code' of DNA, how sequence-dependent properties regulate biological processes, and the role of mechanical forces in genome evolution. His lab develops novel sequencing-based methods and employs machine learning for predictive modeling of DNA mechanics. Recent work explores epigenetic modifications and their impact on DNA mechanics.
- Awards: Royal Society University Research Fellowship
- Lab Focus: Integration of computational, biochemical, and biophysical approaches to study DNA mechanics
- Current Projects: High-throughput analysis of DNA flexibility, nucleosome stability, and mechanotransduction in biological systems
Publications span topics from bacteriophage applications in agriculture to nucleosome dynamics, demonstrating interdisciplinary research bridging physics and molecular biology.
