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Owais Khan serves as an Assistant Professor in the Department of Biomedical Engineering at Toronto Metropolitan University, where he leads research in cardiovascular biomechanics to improve heart disease diagnosis and treatment through engineering-driven approaches combining computational simulations, medical imaging, and biomechanics. His research program focuses on three interconnected pillars: developing physics-based computational models for blood flow simulation in patient-specific anatomies; advancing medical imaging techniques like dynamic CT myocardial perfusion and vessel wall MRI for quantitative physiological assessment; and conducting fundamental biomechanics studies to optimize prosthetic valve designs. This work directly addresses critical clinical challenges including heart surgery complications, aneurysm rupture prediction, and vein graft failure in coronary bypass patients. Khan's publication record demonstrates consistent innovation in cardiovascular computational modeling, with recent work emphasizing personalized medicine through physics-informed neural networks, multi-fidelity uncertainty quantification, and integration of CT perfusion imaging for coronary hemodynamics. His research bridges engineering principles with clinical cardiology to enable virtual treatment planning and risk stratification without additional patient risk. His scientific contributions have been recognized with prestigious awards including the American Heart Association Postdoctoral Fellowship, NSERC Postdoctoral Fellowship, Baxter Young Investigator Award, and MITACS Globalink Research Award. As director of the Cardiovascular Imaging and Modeling Biomechanics Lab (CIMBL), Khan maintains active collaborations with clinicians and radiologists at major hospitals, facilitating direct translation of engineering solutions to clinical cardiovascular medicine through a multi-disciplinary approach focused on personalized treatment strategies.

• Cardiovascular Biomechanics
• Computational Fluid Dynamics
• Medical Imaging
• +3 more

Matthias Friedrich, MD, is a Professor in the Department of Medicine, Faculty of Medicine and Health Sciences at McGill University, and serves as a Senior Scientist at the Research Institute of the McGill University Health Centre (RI-MUHC) at the Glen site. He leads the Cardiovascular Magnetic Resonance (CMR) Research Centre within the Cardiovascular Health Across the Lifespan Program at the Centre for Translational Biology. Dr. Friedrich's research focuses on novel techniques for optimizing and simplifying clinical cardiovascular magnetic resonance (CMR) protocols that require minimal interaction and reduce the need for contrast agents or stress protocols. His work includes the application of novel CMR image reconstruction techniques, machine learning, automated scanning, and the validation of novel imaging biomarkers in clinical studies. Several current projects explore new options for assessing coronary vascular function using breathing maneuvers instead of traditional pharmacological vasodilators or stress protocols as vasoactive triggers. Dr. Friedrich's recent publications demonstrate a strong emphasis on advancing oxygenation-sensitive CMR techniques and applying them to understand myocardial ischemia, myocarditis, and various cardiomyopathies. His work increasingly integrates artificial intelligence and machine learning approaches to enhance diagnostic capabilities, with recent studies focusing on automated detection of hypertrophic cardiomyopathy and other cardiac conditions using deep learning analysis of CMR images. Fellow of the European Society of Cardiology (FESC) Fellow of the American College of Cardiology (FACC) Dr. Friedrich's research program receives significant support from the Family Courtois Foundation through the McGill University Health Centre Foundation. He maintains close collaborations with invasive and non-invasive cardiology, cardiac surgery, and radiology teams at the MUHC, as well as active collaborations with other hospitals in Montreal and academic centers worldwide, including cohort research with the Canadian Alliance for Healthy Hearts and Minds. The CMR Research Centre at McGill University Health Centre, led by Dr. Friedrich, has access to two clinical MRI scanners (Siemens Skyra 3.0T, GE Artist 1.5T) and full-time access to a dedicated MRI system (GE Premier 3.0T) for CMR research. The team is actively developing and validating novel imaging techniques that aim to significantly change diagnostic cardiology practice through improved accessibility, safety, and diagnostic accuracy.

• Cardiovascular magnetic resonance
• myocardial ischemia
• coronary heart disease
• +2 more

Dr. Tami A. Martino is a Professor in the Department of Biomedical Sciences at the Ontario Veterinary College, University of Guelph. She holds the Distinguished Chair in Molecular Cardiovascular Research and is a Career Investigator with the Heart and Stroke Foundation of Canada. Her work bridges circadian biology and cardiovascular medicine, aiming to develop chronotherapeutic interventions for heart disease. Research Focus: Dr. Martino investigates how circadian rhythms influence myocardial infarction, heart failure, hypertension, and inflammatory responses in cardiovascular disease. Her lab employs transgenic models, molecular biology, and preclinical approaches to uncover time-dependent therapeutic targets. Scientific Contributions: She has published extensively in top journals like Cell , Circulation Research , and Nature Reviews Cardiology , with a focus on clock gene regulation, microbiome interactions in heart failure, and sex-specific cardiovascular vulnerabilities. Honors include the Distinguished Chair and Heart and Stroke Foundation Career Investigator award Editorial features in Nature Reviews Cardiology and Trends in Endocrinology & Metabolism Advising: Her lab mentors graduate students Mallory Metcalfe, Vanya Khanna, Robin Harington, and Niru Rameshkumar, fostering interdisciplinary research at the intersection of veterinary and human medicine.

• Circadian Medicine
• Cardiovascular Research
• Heart Disease
• +5 more

Peter Backx is a Full Professor in the Department of Biology at York University and Canada Research Chair in Cardiovascular Biology. He is also an Emeritus Professor at the University of Toronto and a Senior Scientist at the University Health Network. His academic journey includes a B.Sc., M.Sc., DVM (University of Guelph), and Ph.D. (University of Calgary), followed by postdoctoral training at Johns Hopkins University. His research focuses on cardiac physiology, ion channels, arrhythmias, and stem cell applications in cardiovascular biology. Dr. Backx has secured over $14M in research funding and published over 200 articles in top journals. He has supervised 26 graduate students and 17 postdoctoral fellows. His awards include Fellowships from the Royal Society of Canada and American Heart Association, as well as the Lowell Langille Mentorship Award. His work emphasizes mechanisms underlying heart disease, including atrial fibrillation and heart failure, with a focus on translational applications like tissue-specific drug delivery. Key research areas include ion transport, myocardial signaling, and cardiac development using pluripotent stem cells. He has pioneered models of atrial fibrillation and engineered cardiac tissues. Recent studies explore TNF-alpha’s role in exercise-induced atrial remodeling and therapeutic strategies for Duchenne muscular dystrophy. Dr. Backx’s labs integrate electrophysiology, proteomics, and tissue engineering to advance cardiovascular medicine.

• Cardiac Physiology
• Cardiac Electrophysiology
• Arrhythmias
• +4 more

Dr. Robert Tsushima is an Associate Professor and Chair of the Biology Department at York University's Faculty of Science. His research focuses on understanding the mechanisms underlying heart disease and diabetes, particularly investigating ion channel regulation and SNARE protein interactions in pancreatic and cardiac cells. He explores how cholesterol influences islet cell function and examines protective mechanisms in myocardial ischemia. Research Areas His work spans Animal Physiology , Cell Biology , and Ion Channel Dynamics , with a focus on cardiovascular and metabolic disorders. Key topics include insulin secretion pathways, cholesterol's role in stimulus-secretion coupling, and the interplay between SNARE proteins and ion channels in cellular processes.

• Heart Disease
• Diabetes
• Ion Channels
• +3 more

Justin Deniset is an Assistant Professor at the Cumming School of Medicine , University of Calgary , holding dual appointments in the Department of Cardiac Sciences and Department of Physiology and Pharmacology . His research focuses on cardio-immunology , investigating how the immune system contributes to cardiac function and repair post-injury. Education: Undergraduate at St-Boniface University, Ph.D. in Physiology and Pathophysiology at University of Manitoba under Dr. Grant Pierce, Post-Doctoral Fellow at University of Calgary under Dr. Paul Kubes Research Areas: Immune regulation in cardiac repair, vascular remodelling, inflammation in ischemic injury, and therapeutic applications of biomaterials His recent publications in Journal of Experimental Medicine and Immunity highlight his work on neutrophil dynamics, biomaterials for cardiac regeneration, and inflammatory pathways post-surgery. Collaborations with the Libin Cardiovascular Institute emphasize translational approaches to cardiovascular disease. He maintains a laboratory in the HRICGC47 facility, supported by lab manager Ben Lee and administrative assistant Brian Kitagawa .

• Cardio-Immunology
• Vascular Biology
• Inflammation
• +3 more

Dr. Catherine Kells is a Professor in the Department of Medicine at Dalhousie University’s Faculty of Medicine, where she serves in the Division of Cardiology. She is an accomplished clinician, educator, researcher, and administrator with over three decades of service since joining in 1990. Dr. Kells holds leadership roles in national cardiovascular organizations, notably serving as President Elect of the Canadian Cardiovascular Society. Her research interests are focused on improving diagnosis, treatment, and management of heart disease, with particular expertise in cardiac transplantation, myocardial ischemia, STEMI, and congenital heart disease. She is deeply involved in clinical research, quality improvement, and medical education, contributing to national guidelines and policy. Dr. Kells’ recent publications center on adult congenital heart disease care quality, interventional cardiology training standards, tele-education in cardiology, and healthcare workforce challenges. Her work reflects a strong commitment to clinical excellence, education innovation, and health systems improvement. Gold Quality Award for “Changing to Meet Patient Needs”, Heart Health/Critical Care/Medicine, Capital District Health Authority (May 2013) Recognition of Outstanding Leadership, Division of Cardiology (1996 – 2005) Outstanding Contributions to Education, Department of Medicine (2003) Dr. Kells has served as principal or co-investigator on multiple clinical trials and research initiatives. She has contributed to national education and training frameworks, advised medical technology firms, and played key roles in professional governance through the Royal College, American College of Cardiology, and Canadian Cardiovascular Society. She has trained numerous learners and advanced cardiology education through innovative delivery methods like videoconferencing. She is actively engaged in the Division of Cardiology at the QEII Health Sciences Centre in Halifax, contributing to patient care, research, and academic leadership. Her work is integrated across clinical, educational, and administrative domains, supporting both individual patient outcomes and systemic improvements in cardiovascular care.

• Cardiology
• Heart Disease
• Cardiac Transplantation
• +7 more

Bianca D'Antono is a Full Professor at the Department of Psychology, Faculty of Arts and Sciences, University of Montreal, and Director of the Hearts and Souls Research Unit in Behavioral and Complementary Medicine at the Montreal Heart Institute (ICM). Her research explores mind-body interactions in cardiovascular disease, focusing on psychological and psychophysiological determinants. University of Montreal - Full Professor, Department of Psychology Montreal Heart Institute (ICM) - Director of Behavioral & Complementary Medicine Research Unit Key methodologies: Experimental studies, physiological monitoring, ecological data validation Research Interests: The Hearts and Souls laboratory investigates: Psychological distress mechanisms in cardiovascular patients Gender differences in stress response and autonomic function Stress-induced inflammatory pathways Mindfulness-based interventions for coronary risk Psychosomatic effects of childhood maltreatment Article Trends: Recent publications demonstrate expertise in: Mind-body interactions in chronic illness Stress response biomarkers Gender-specific cardiovascular psychopathology Digital health interventions Psychosocial predictors of disease progression Scientific Awards: Top 10% reviewer - Annals of Internal Medicine Lucien Campeau Prize (2011) Meritorious Student Award (2013) FRSQ Junior Research Fellow (2007-2012) Supervision: Directed 10+ theses since 2015 including Alexandra Connor (PhD 2024), Ann Xiuli Chicoine (MSc 2024), and Vicki St-Arnaud (MSc 2023).

• Cardiovascular Psychology
• Behavioral Medicine
• Psychophysiology
• +5 more

Po-Yin Cheung serves as an Adjunct Professor in the Department of Pharmacology at the University of Alberta, where she conducts research on neonatal cardiovascular physiology and pharmacology with a focus on hypoxia-reoxygenation injury in newborns. Her academic credentials include: MBBS from the University of Hong Kong (1985) PhD in Pharmacology from the University of Alberta (1998) FRCP from Canada (2001) and Edinburgh (2002) Dr. Cheung's research investigates novel interventions for neonatal asphyxia recovery, examining cardiovascular drug effects during hypoxia-reoxygenation using newborn piglet models. Her laboratory studies systemic and regional circulations, platelet functions, and long-term outcomes in critically ill neonates. Key methodologies include near-infrared spectroscopy, blood gas analysis, and resuscitation technique evaluation. Analysis of her 2016-2017 publications reveals dominant themes in neonatal resuscitation optimization, oxygen management protocols, and outcome prediction for asphyxiated/preterm infants. Her work consistently bridges basic science (piglet models) and clinical applications, with strong international collaborations focusing on ventilation devices, chest compression techniques, and pharmacological interventions. Dr. Cheung mentors research associates and technicians in the Neonatal Sciences Laboratory, including Dr. Tze-Fun (Raymond) Lee, Dr. Megan Schmolzer, and Research Technician Min Lu. While no specific grants are documented, her work involves substantial collaborative projects with clinical and international partners. The Neonatal Sciences Laboratory, located in the Medical Sciences Building (Room 9-50), specializes in hypoxia-reoxygenation injury models and cardiovascular drug testing. Current projects evaluate tidal volume delivery, oxygen concentration effects, and myocardial perfusion during resuscitation, directly informing neonatal care guidelines.

• Neonatal Asphyxia
• Cardiovascular Physiology
• Pharmacology
• +3 more

Dr. T. Alexander Quinn is a Professor in the Department of Physiology and Biophysics at Dalhousie University's School of Biomedical Engineering. His research explores cardiac autoregulation, mechano-electric coupling, and arrhythmia mechanisms using multiscale experimental and computational models across species. Based in Halifax, Nova Scotia, he actively recruits graduate students for Fall 2025 research projects. BSc (McGill University) MSc & PhD (Columbia University) Postdoctoral training: University of Oxford, Imperial College London Research Focus : Cardiac autoregulation mechanisms from organ to subcellular levels Mechano-electric interactions in heart rhythm dynamics Computational modeling of cardiac function across species Zebrafish and mammalian models for cardiac research Development of targeted anti-arrhythmic therapies Publication Trends : Recent work spans zebrafish cardiac modeling (2025, 2024), ischemia-induced arrhythmogenesis (2025), sinoatrial node dynamics (2022), and historical perspectives on cardiac biophysics (2022). Key methodologies include optogenetics, computational simulations, and multispecies electrophysiology. Scientific Recognition : King Charles III Coronation Medal Sir Harcourt Caughey Award (Auckland Medical Research Foundation) J.A.F. Stevenson Award (Canadian Physiological Society) Dalhousie Medical Research Foundation Award Heart & Stroke Foundation of Nova Scotia Award Teaching Roles : PHYL 4680/5568: Advanced Cardiovascular Physiology PHYL 2044: Human Systems Physiology BMNG 5062: Biomedical Engineering Foundations MNSC 6101: Cellular Neuroscience MED 2: Metabolism II

• Cardiovascular Physiology
• Cardiac Electrophysiology
• Mechano-Electric Coupling
• +3 more

Philip Devereaux is a Professor in the Department of Health Research Methods, Evidence, and Impact at McMaster University's Faculty of Health Sciences. His research focuses on perioperative medicine, cardiovascular risk prediction, and clinical trial methodology. Canada Research Chair McMaster University Research Interests include: Perioperative cardiovascular complications Machine learning applications in surgical risk assessment Thrombosis and bleeding in surgical patients Clinical trial design and meta-analysis Postoperative delirium and cognitive decline Health outcomes in noncardiac surgery Recent Publications highlight advancements in: Predictive modeling for myocardial injury Anticoagulation strategies in surgery AI-driven risk stratification systems Cardiovascular implications in dialysis patients Delirium prevention in cardiac surgery Optimizing surgical outcomes through virtual care Scientific Leadership : Principal investigator of major trials (VISION, LAAOS III, HIP ATTACK) Recipient of significant CIHR funding Contributor to ESC and ESAIC guidelines Developer of standardized outcome measures (COMPAC)

• Perioperative Medicine
• Cardiovascular Risk Prediction
• Clinical Trials
• +6 more

Jolanta Gutkowska is a Full Professor at the Department of Medicine, Faculty of Medicine, University of Montreal. She is affiliated with the CRCHUM (Centre de recherche du Centre hospitalier de l'Université de Montréal) and CHUM (Centre hospitalier de l'Université de Montréal). Research Interests: Her work focuses on stem cell differentiation into cardiomyocytes, oxytocin's role as a cardiovascular hormone, and the therapeutic potential of biologically active peptides. She investigates mechanisms of cell protection, metabolic and cardiovascular complications in diabetes, and signaling pathways in myocardial ischemia-reperfusion. Supervised Students: Paul Tan (Ph.D. 2016) - Prorenin receptor in obesity and cardiometabolic complications Araceli Gonzalez Reyes (M.Sc. 2013) - Oxytocin in myocardial ischemia-reperfusion Suzanne Dominique Genest (M.Sc. 2013) - Exercise training effects in preeclampsia models Yessoufou Aliou (M.Sc. 2012) - Oxytocin's metabolic and cardiovascular effects in hypertension models Christophe Fadainia (M.Sc. 2012) - Atrial natriuretic peptide in cardiac differentiation Stéphanie Falcao (Ph.D. 2010) - Mouse models of preeclampsia and exercise effects Yang Wang (M.Sc. 2009) - Oxytocin receptor modulation in right ventricular hypertrophy Valérie Morin (M.Sc. 2008) - Pharmacokinetics/pharmacodynamics of oxytocin in rats Malgorzata Miszkurka (M.Sc. 2006) - Vasopressinergic system in cardiac maturation Sheila Ernest (M.Sc. 1996) - Prenatal morphine exposure effects on atrial natriuretic factor Major Research Projects: PLEIOTROPIC EFFECTS OF OXYTOCIN (2009-2017) - Funded by CIHR MECHANISM OF CELL PROTECTION BY OXYTOCIN (2012-2014) - Funded by NSERC OXYTOCIN AS CARDIOVASCULAR HORMONE (2008) - Single-year project DIABETES-RELATED CARDIOMETABOLIC PROTECTION (2009-2013) - Oxytocin and natriuretic peptides

• Oxytocin in cardiovascular function
• Stem cell differentiation into cardiomyocytes
• Biologically active peptides
• +4 more

Charles Leduc serves as an Associate Clinical Professor in the Department of Pathology and Cell Biology at Université de Montréal's Faculty of Medicine, where his clinical practice and research focus on pulmonary, cardiovascular, and mediastinal diseases through histopathological analysis. His academic foundation includes: Medical degree from McGill University, Quebec Master of Science in Pharmacology from Université de Montréal, Quebec Fellowship in Thoracic Pathology at Memorial Sloan Kettering Cancer Center, USA Fellowship in Cardiovascular Pathology at Mayo Clinic, USA Dr. Leduc's research centers on disease mechanisms in cardiac and pulmonary pathology, with emphasis on tumor characterization, vascular anomalies, and diagnostic methodologies. His work bridges clinical practice with laboratory investigation, frequently examining histopathological correlates of sudden cardiac death, neoplastic transformations, and immunotherapy complications. Collaborative efforts span cardiothoracic surgery, oncology, and molecular genetics disciplines to address complex diagnostic challenges. Analysis of his 14 publications (2012-2019) reveals consistent expertise in cardiovascular pathology (43% of works), particularly cardiac tumors and congenital heart disease complications, alongside significant contributions to pulmonary pathology (36%) including lung cancer biomarkers and thoracic neoplasms. His research demonstrates methodological diversity across histopathology, molecular genetics, and clinical case analysis, with notable book chapter contributions to pulmonary pathology reference works. Dr. Leduc contributes to medical education through the department's Virtual Histology Lab, a digital resource supporting pathology training, and maintains clinical responsibilities at affiliated teaching hospitals.

• Pulmonary Pathology
• Mediastinal Pathology
• Cardiovascular Pathology
• +3 more

Michael Guevara is a retired Associate Professor in the Department of Physiology at McGill University, affiliated with the McIntyre Medical Sciences Building. His research focuses on cardiovascular physiology, particularly the dynamics of cardiac arrhythmias and spiral wave formation using computational models. He holds degrees from McGill University (B.Sc., B.Eng., Ph.D.). Research Interests: Investigating mechanisms underlying cardiac arrhythmias through ionic modeling of spiral waves in ischemic ventricular muscle. His work aims to understand arrhythmia initiation and develop control strategies. Key areas include nonlinear dynamics, bifurcation analysis, and phase resetting in biological systems. Labs: The Guevara Lab (www.medicine.mcgill.ca/physio/guevaralab) explores cardiac electrophysiology and arrhythmia dynamics. He is no longer accepting students but has contributed significantly to understanding ischemia-driven arrhythmias and spiral wave behavior. Professional Contributions: Published extensively on cardiac physiology, nonlinear dynamics, and arrhythmia mechanisms. Collaborated with experts like Leon Glass and Michael C. Mackey on interdisciplinary approaches to cardiac dynamics.

• Cardiovascular Physiology
• Electrophysiology
• Cardiac Arrhythmias
• +3 more

Pierre PAGÉ is a Clinical Professor in the Department of Surgery at the Faculty of Medicine, University of Montreal. His research focuses on cardiac electrophysiology, arrhythmia surgery, and the autonomic nervous system's role in atrial fibrillation and ventricular tachycardia. He is affiliated with the Centre de recherche du CIUSSS Nord-de-l’île-de-Montréal and the Institut de cardiologie de Montréal (ICM). Education: No formal education details provided in the text. His research explores mechanisms of neuromodulation in cardiac arrhythmias, with a focus on neuroablation techniques and autonomic nervous system interactions. Key areas include electrophysiological mapping, atrial fibrillation vulnerability, and the impact of surgical interventions on cardiac neural pathways. Recent articles highlight his work on postoperative outcomes following cardiac surgeries, atrial fibrillation mechanisms in animal models, and the comparative effectiveness of revascularization strategies. He has contributed to clinical trials like EXCEL, evaluating PCI vs. CABG in left main disease patients. No scientific awards explicitly mentioned. Supervised over five Master's students, including Emmanuel Moss (2011) and Frédéric Jacques (2008). His grant-funded research includes projects on cardiac nervous system remodelling during myocardial ischemia and spinal cord stimulation effects. Labs/teams: Active in CIUSSS Nord-de-l’Île-de-Montréal and ICM, collaborating on electrophysiological studies and surgical innovations.

• Cardiac Electrophysiology
• Arrhythmia Surgery
• Autonomic Nervous System
• +3 more