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Ahmet AcarView profile

Associate Professor

• Cancer Biology
• Precision Medicine
• Drug Resistance Mechanisms
• +3 more

Dr. Ahmet Acar is an Associate Professor at the Department of Biological Sciences, Middle East Technical University (METU), Ankara, Turkey. He leads the Cancer Precision Medicine and Drug Resistance Laboratory, focusing on understanding mechanisms of drug resistance in cancer. His research integrates experimental models, next-generation sequencing, and deep learning to address clinical challenges in cancer therapy. Dr. Acar holds a B.Sc. from METU's Biological Sciences department and a Ph.D. from the Cancer Research UK Manchester Institute. He completed postdoctoral training at the Institute of Cancer Research, London, and the University of Manchester. Research Interests: Drug resistance mechanisms, precision oncology, tumor microenvironment modeling, patient-derived organoids, computational pathology, and evolutionary cancer biology. His lab develops 2D/3D co-culture systems, PDO biobanks, and AI-driven histopathology tools to improve treatment strategies. Recent Work Trends: Recent publications emphasize tumor evolution modeling, matrix mechanics in drug resistance, and AI applications in histopathology. Collaborations with hospitals in Turkey and Europe support PDO biobank initiatives. His team explores evolutionary steering strategies to exploit collateral drug sensitivities. Labs/Teams: Precision Medicine and Drug Resistance Lab at METU focuses on interdisciplinary approaches combining wet-lab experiments with computational methods. Current projects include ex vivo tumor modeling and AI-driven diagnostic tools for oncology.

• Machine Learning
• Genomics
• Gene Regulatory Networks
• +3 more

Sushmita Roy is a Professor at the University of Wisconsin–Madison, affiliated with the Department of Computer Sciences and the College of Letters and Science. Her research focuses on developing computational methods in statistical machine learning to understand gene regulatory networks in living cells, particularly under environmental, developmental, disease, and evolutionary contexts. She explores bulk and single-cell genomic data integration to study processes like cell fate specification, host-microbe interactions, and diseases such as cancer and neurodevelopmental disorders. Her work emphasizes three key areas: inference of genome-scale transcriptional networks, evolutionary analysis of regulatory networks, and 3D genome organization dynamics. Roy’s lab collaborates across disciplines, leveraging genomic data from plant and mammalian systems. She has contributed to methodologies for analyzing chromatin accessibility, single-cell profiling, and network-based models of pathogen systems. Her affiliations include Wisconsin Institutes for Discovery, and she is a leader in computational biology and systems genomics research.

Helmuth GehartView profile

Professor

• Stem Cell Biology
• Cancer Biology
• Regenerative Medicine
• +2 more

Prof. Dr. Helmuth Gehart is a faculty member at the Institute of Molecular Health Sciences , ETH Zurich . He leads the Tumor and Stem Cell Dynamics research group, focusing on dynamic cell identity in regeneration and cancer. Research Interests : Stem cell-environment interactions, organoid technology, single-cell sequencing, and mechanisms of tissue repair/tumorigenesis. Publications : 10+ articles (2015-2024) on organoid models, stem cell dynamics, and cancer biology.

• Microbiology
• Infectious Diseases
• Cell Biology
• +7 more

Manuel R. Amieva is a Professor at Stanford University School of Medicine , holding joint appointments in Pediatrics - Infectious Diseases and Microbiology & Immunology . He is also a member of the Maternal & Child Health Research Institute (MCHRI) . His clinical practice at Stanford Medicine Children's Health focuses on pediatric infectious diseases. Education: Medical Education: Stanford University School of Medicine (1997) Fellowship: Stanford University Pediatric Infectious Disease Fellowship (2004) Internship & Residency: Stanford Health Care at Lucile Packard Children's Hospital (1998-1999) Dr. Amieva's research investigates host-pathogen interactions at epithelial barriers, with specific expertise in Helicobacter pylori , Listeria monocytogenes , Salmonella enterica , and Staphylococcus aureus . His lab develops innovative organoid culture systems with controlled polarity to study microbial colonization and oncogenic mechanisms. Key discoveries include: H. pylori's manipulation of epithelial junctions via the CagA protein Listeria's exploitation of cell extrusion sites for invasion Staphylococcus toxin interactions with adherens junctions Gastric stem cell activation by pathogens Recent publication trends show continued leadership in infectious disease mechanisms (2020-2025), with a focus on: Pathogen-specific epithelial breach strategies Organoid modeling of viral/bacterial interactions Redox-dependent host factor regulation Single-cell spatial transcriptomic analyses Multi-institutional educational frameworks His scientific collaborations span disciplines including: Gastric cancer genomics initiatives COVID-19 lung infection models Stem cell-microbe interactions Medical education reform projects Dr. Amieva maintains active clinical research while mentoring students in both the Microbiology & Immunology and Pediatrics programs. His lab at Stanford employs advanced 3D confocal microscopy and organ-on-a-chip technologies to visualize epithelial colonization dynamics.

Waldemar KolanusView profile

Professor

• Molecular Immunology
• Cell Signaling
• Signal Transduction Pathways
• +4 more

Prof. Waldemar Kolanus leads the Molecular Immunology and Cell Biology department at the University of Bonn's Life & Medical Sciences Institute (LIMES) . His research bridges immunoregulation , stem cell dynamics , and metabolic stress responses in immune cells. Unit 2 member at LIMES Principal investigator in SFB 704 and ImmunoSensation Cluster Leads a multidisciplinary lab with postdocs, PhD students, and technical staff His work focuses on intracellular signaling pathways connecting immune activation to tissue homeostasis, particularly through: Cytohesin proteins in integrin-mediated adhesion and migration TRIM71 in stem cell regulation and congenital hydrocephalus High-salt environments affecting macrophage function Publication trends show expertise in immune cell migration , genetic models , and chemical inhibition , with frequent use of mice and zebrafish for in vivo studies. Key articles explore: TRIM71's dual role in auditory development and germ cell maintenance Cytohesin family's Golgi regulation and insulin signaling Ruxolitinib's off-target migration inhibition of dendritic cells Contact details: Address: LIMES Institute, Carl-Troll-Straße 31, Bonn Email: kolanus.sekretariat@uni-bonn.de Phone: +49 228 73-62788

• Bioengineering
• Tissue Engineering
• Regenerative Medicine
• +4 more

Houman Savoji is an Associate Professor in the Department of Pharmacology and Physiology at the Faculty of Medicine, University of Montreal. He is also a full-time researcher at the CHU Sainte-Justine Research Center and principal investigator in regenerative medicine, organs-on-chip, and bioprinting at TransMedTech Institute. Dr. Savoji received his PhD in Biomedical Engineering from the Institute of Biomedical Engineering at Polytechnique Montréal in 2016. He then completed a postdoctoral fellowship at the Institute of Biomaterials and Biomedical Engineering at the University of Toronto. His research expertise combines advanced manufacturing technologies (micro- and nano-fabrication, 3D bioprinting, microfluidics, cell electrospinning) with functional and composite materials for applications in tissue engineering, regenerative medicine, and organs-on-chip. His work focuses on the design, development, optimization, implementation, and characterization of innovative functional biomaterials using emerging engineering technologies, with particular emphasis on cardiac tissue engineering and biomimetic pulmonary heart valves for pediatric patients. Dr. Savoji has published extensively on biomaterials, tissue engineering, 3D bioprinting, and organ-on-chip technologies. His recent publications demonstrate expertise in viscoelastic characterization of soft tissues, engineering immune responses to biomaterials, ceramic engineering for biomedical applications, and advanced 3D bioprinting techniques for cardiac and vascular tissue engineering. 2017-2020, Postdoctoral Research Grant, CIHR 2017-2019, Postdoctoral Research Grant, FRQNT 2017-2018, Human Society of International Grant, Human Toxicity Assessment Project 2016, CR-CHUM Research Center Award 2015, Star Student-Researcher Award, FRQNT 2014-2015, Jane and Frank Warchol Fellowship, Society of Vacuum Coaters Foundation 2013, Institute of Textile Science Award 2012-2015, Excellence Doctoral Scholarship for Foreign Students, FRQNT Dr. Savoji has supervised Master's students including Ines Barrakad (2024) working on 'Advanced manufacturing technologies versus molding of corneal implants: 3D printing vs molding of a Keratoprosthesis' and Zineb Ajji (2023) researching 'Development of perfusable patches by 3D bioprinting for potential application in cardiac tissue regeneration.' He has secured numerous research grants from organizations including CIHR, NSERC, FRQNT, FRQS, MITACS, and others for projects related to 3D bioprinting of cardiac tissues, biomimetic heart valves, and other tissue engineering applications. The Savoji Laboratory, located within the Department of Pharmacology and Physiology and Institute of Biomedical Engineering of the Faculty of Medicine of the University of Montreal, the Research Center of the CHU Sainte-Justine (CHUSJ), and the TransMedTech Institute, focuses on multidisciplinary research involving 3D bioprinting using stem-cell derived human cardiac cells to fabricate functional cardiac tissues for transplantation and drug discovery applications.

• Biomaterials
• Tissue Engineering
• Regenerative Medicine
• +12 more

Professor Hala Zreiqat AM is a leading biomedical engineer at The University of Sydney , serving as the Director of the ARC Training Centre for Innovative BioEngineering . A Fellow of all major Australian academies (AAS, ATSE, FAHMS, FRSN), she develops 3D printed bioceramics for bone regeneration while championing diversity through initiatives like the IDEAL Society and BIOTech Futures mentorship program. Her work bridges academia, clinical practice, and industry in musculoskeletal research . Research Focus: Her lab creates synthetic bone scaffolds that mimic natural bone architecture, strength, and porosity, enabling non-rejected bone regeneration via patient-matched implants. Key applications include orthopaedic, dental, and maxillofacial repair , with over $18M in competitive funding and multiple patents. Current projects explore AI-driven scaffold performance prediction and anti-senescence strategies for aging-related bone loss. Scientific Trends: Recent publications highlight 3D printed nanovoxelated ceramics , antisenescence biomaterials , and multifunctional theranostic platforms . Her team integrates machine learning for scaffold design, atom probe tomography for interface analysis, and two-photon imaging for cellular monitoring in 3D environments. 2021-2022 Fulbright Senior Scholar 2018 NSW Premier's Woman of the Year 2019 Eureka Prize for Innovative Use of Technology Fellow of Australian Academy of Science (2021) Over $18M in research funding Teaching & Leadership: She designed core courses like Tissue Engineering and Nanomaterials in Medicine , mentoring 158 students in 2020 alone. As Chair of CAAR (2020-2023), she strengthens Australia-Arab collaborations. Her lab trains early-career researchers , with alumni now in academia and industry.

Simon SchäferView profile

Professor

• Neuroscience
• Developmental Biology
• Stem Cell Research
• +4 more

Prof. Dr. Simon Schäfer leads the Schäfer Lab at the Technische Universität München , focusing on engineering advanced organoid systems to study human brain development, disease modeling, and repair mechanisms. His work bridges stem cell biology, gene editing, and bioengineering to develop personalized therapies for brain disorders. Stem Cell & Organoid Technology Neurodevelopmental Mechanisms Neurodegenerative Disease Models Gene Editing & Neuroimmune Interactions Translational Neuroscience Recent research emphasizes brain organoid development, microglia phenotypes, and neurodevelopmental timing anomalies in autism. His team’s work also explores zika virus interactions with glioblastoma stem cells and neuronal plasticity in psychiatric disorders. Scientific awards and funding include support from the Deutsche Forschungsgemeinschaft (DFG), Brain & Behavior Research Foundation (BBRF), and Munich Cluster for Systems Neurology (SyNergy). Collaborations span institutions like the TUM Center for Organoid Systems. Advises 6 students (2 PhD, 1 MSc, 3 associated) Labs include Schäfer Lab, COS@TranslaTUM Contact: simon.schafer@tum.de

Silvia SantosView profile

Researcher

• Developmental Biology
• Cell Biology
• Cell Cycle & Chromosomes
• +3 more

Silvia Santos is a Group Leader at the Francis Crick Institute, leading the Quantitative Stem Cell Biology Lab since January 2018. Her research focuses on understanding cell decision-making during transitions, specifically cell division and differentiation in early development using human embryonic stem cells. She combines experimental techniques with theoretical approaches, including advanced microscopy, genomics, and computational modeling. Education and Career: PhD in Molecular and Cell Biology from EMBL-Heidelberg (2008), followed by postdoctoral training at Stanford University (2009-2014). She held an MRC Career Development Award at Imperial College London (2014-2017) before joining the Crick. Her work emphasizes interdisciplinary methods to study cellular processes in health and disease. Research Interests: Spatial-temporal control in cell decisions, stem cell differentiation, cell cycle regulation, and modeling embryonic development. She advocates for women in science and mentorship programs for early-career researchers. Key Achievements: Recipient of Marie Curie E-Star, EMBO, and HFSP fellowships. Recognized with the BioModels’ Model of the Year 2023 for contributions to systems biology. Her lab develops models like gastruloids to study embryonic development. Grants and Mentorship: Supported by MRC and other grants. Committed to fostering excellence in training and mentorship, previously chairing mentorship initiatives at Imperial College London. Labs and Teams: Quantitative Stem Cell Biology Lab at the Crick, collaborating with interdisciplinary teams on projects involving proteomics, genomics, and high-throughput screening.

• Biomaterials
• Peripheral Nerve Injury
• Neuromuscular Modeling and Repair
• +2 more

Suradip Das is a Research Assistant Professor in the Department of Neurosurgery at the Perelman School of Medicine, University of Pennsylvania, where he serves as a Senior Research Investigator. His work bridges neural engineering and regenerative medicine to address critical challenges in nerve and muscle repair. His academic training includes: B.Tech in Biotechnology from Heritage Institute of Technology (2010) PhD in Biosciences and Bioengineering from Indian Institute of Technology Guwahati (2016) Dr. Das specializes in biomaterials development , peripheral nerve injury models , neuromuscular interface engineering , and stem cell-based regeneration . His research pioneers innervated tissue-engineered muscle constructs, demonstrating how motor neurons and endothelial cells synergistically enhance skeletal myocyte maturation. He innovates custom mechanobioreactors that apply tensile forces to guide nanofiber alignment for optimal myofiber formation, significantly advancing volumetric muscle loss treatments. Analysis of his 15 most recent publications reveals a dominant focus on neuromuscular regeneration (75% of articles), with emerging exploration of psychedelic compounds in neural repair. His work consistently integrates human iPSC-derived models , multi-cellular co-cultures , and large-animal validation to address translational gaps. Key trends include optogenetic control of motor units (2023), porcine nerve injury models (2020), and the critical role of pre-innervation in creating pro-regenerative microenvironments (2020-2022). As a core member of the Cullen Lab, Dr. Das collaborates on developing biofabricated neural microtissues for delayed nerve fusion and rapid functional recovery. His research directly informs clinical strategies for peripheral nerve repair and muscle regeneration through rigorous mechanistic studies and innovative engineering solutions.

• Planarian Regeneration
• Stem Cell Biology
• Wnt Signaling Pathways
• +6 more

Christian P Petersen, PhD is a Professor in the Department of Cell and Developmental Biology at the Weinberg College of Arts and Sciences , Northwestern University Feinberg School of Medicine. His research focuses on molecular mechanisms underlying regeneration in planarians and other organisms. PhD: MIT (2006) Research Interests: Planarian regeneration and tissue patterning Wnt signaling pathway regulation Stem cell biology in regenerative contexts Neurogenesis and injury response Molecular mechanisms of tissue repair Affiliations: Center for Reproductive Science Robert H. Lurie Comprehensive Cancer Center

Su Ryon ShinView profile

Assistant Professor

• Bioengineering
• Tissue Engineering
• 3D Bioprinting
• +7 more

Dr. Su Ryon Shin is an Assistant Professor in the Division of Engineering in Medicine at Harvard Medical School and Brigham and Women's Hospital (BWH) in Cambridge, MA. She leads an active research laboratory focused on bioengineering, tissue engineering, and regenerative medicine, with particular expertise in 3D bioprinting, biomaterials, and organ-on-a-chip technology. Her research interests span biohybrid robotics, decellularized extracellular matrix, stem cell-based tissue engineering, and volumetric muscle regeneration . Dr. Shin's work integrates advanced biomaterials with cellular systems to create innovative solutions for tissue regeneration and disease modeling. She has pioneered approaches using human stem cell-derived materials for volumetric tissue regeneration and developed biohybrid neuromuscular robots powered by living cardiac muscle cells. Her publication record demonstrates consistent productivity with over 180 publications, including numerous first/senior author papers in high-impact journals like Science Robotics, Advanced Materials, and Nature Reviews Bioengineering . Her work shows a clear progression from fundamental biomaterials development to increasingly complex tissue engineering applications and translational research. Dr. Shin has received significant recognition including being named a 2025 BWH Health & Technology Innovation Awardee , Highly Cited Researcher 2024 by Web of Science, and multiple Stepping Strong Innovator Awards (2015, 2018, 2020). Her research has been featured in Nature Reviews Bioengineering for breakthrough work on biohybrid robots. She actively mentors students and postdocs, with former lab members accepted to prestigious programs like MIT's PhD program in Chemical Engineering. Her collaborative approach is evident through numerous interdisciplinary projects with researchers across Harvard Medical School, BWH, and international institutions.

Athina E MarkakiView profile

Professor

• Tissue Engineering
• Biomaterials
• Regenerative Medicine
• +3 more

Professor Athina E Markaki serves as Professor of Materials & Biomedical Engineering in the Department of Engineering at the University of Cambridge, leading research in advanced biomaterials and tissue engineering solutions for regenerative medicine with emphasis on vascularization and tubular scaffold development for human conduit replacement. Her academic credentials include a Diploma in Metallurgical Engineering (8.6/10) from the National Technical University of Athens and a PhD in Materials Science from the University of Cambridge. Markaki's research program centers on vascularisation techniques for clinically relevant tissue dimensions and tubular scaffolds to replace diseased or damaged human conduits, integrating biomaterials science with regenerative medicine principles. Key applications span liver tissue engineering, neural crest-derived stem cell differentiation, and vascular graft development, with strong translational focus on orthopaedic and cardiovascular medical devices. Analysis of her recent publications reveals dominant trends in biomimetic scaffold design, particularly collagen-based tubular structures and hydrogel systems for vascularized tissue constructs. Her work demonstrates interdisciplinary convergence of AI-driven retinal assessment, glioblastoma modeling, and self-healing cementitious materials, with consistent emphasis on clinically applicable regenerative solutions for liver, bone, and neural tissues. Her distinguished scientific contributions are recognized by major awards: Rosetrees Trust 2017 Interdisciplinary Award European Research Council (ERC) Starting Grant (2010) Advanced EPSRC Fellowship (2005) De Montfort Award at SET for Britain National Event (2004) Young Scientist Prize 2003 (5th Euromech Solid Mechanics Conference) Multiple academic excellence awards from Greek foundations Markaki directs a well-funded research program including ERC and EPSRC grants, mentoring graduate students in tissue engineering while teaching core engineering curricula covering plastic deformation, fracture mechanics, and medical materials design. Her group maintains strong industry and clinical partnerships to advance regenerative technologies. Her laboratory, accessible via http://www-memti.eng.cam.ac.uk/, specializes in vascularized tissue constructs and tubular scaffolds using laser-based manufacturing, biomimetic design, and hydrogel engineering to address critical challenges in tissue replacement and disease modeling.

Parisa HosseinzadehView profile

Assistant Professor

• Protein Design
• Computational Biochemistry
• Biosensors
• +3 more

Parisa Hosseinzadeh is an Assistant Professor in the Department of Bioengineering at the University of Oregon. Her research focuses on computational protein design and structure-guided rational protein/peptide engineering, with applications in enzyme design, biosensors, and biomedical solutions. She holds a B.Sc. from the University of Tehran, a Ph.D. from the University of Illinois (advisor: Yi Lu), and a postdoc at the University of Washington in David Baker's lab. Her lab emphasizes interdisciplinary approaches at the intersection of computer science, chemistry, and biology, prioritizing diversity and inclusion in STEM. Key projects include designing cyclic peptides as enzyme inhibitors, developing methods for tuning redox potentials in metalloproteins, and creating tools to combat biomedical challenges. Lab members include postdocs, graduate students (e.g., Noora Azadvari, Andrew Powers), and undergraduates. Notable achievements include NSF grants, the Baxter Foundation Award, and the Hans Horse Meyer Award. The lab also emphasizes mentorship, collaborative culture, and outreach initiatives.

Franz Lennard RicklefsView profile

Professor

• Neurosurgery
• Neuro-oncology
• Molecular Neurobiology
• +5 more

Prof. Dr. med. Franz Lennard Ricklefs is a Senior Physician and Head of the Working Group at the Department of Neurosurgery, University of Hamburg Faculty of Medicine. He is a Medical Specialist in Neurosurgery with cross-disciplinary expertise in neuro-oncology, molecular pathology, and extracellular vesicle research. Affiliations: University Medical Center Hamburg-Eppendorf (UKE), European Liquid Biopsy Society (ELBS), International Consortium on Meningiomas (ICOM) Research Interests: His work focuses on neurosurgical oncology, particularly glioblastoma and meningioma pathobiology. He investigates DNA methylation patterns, extracellular vesicle biomarkers, and liquid biopsy implementation in clinical neuro-oncology. Additional interests include surgical outcomes for epilepsy and aneurysm management. Article Trends: Over the last decade, Dr. Ricklefs has published extensively on: Extracellular vesicle applications as liquid biopsy markers DNA methylation subclasses for glioblastoma and meningioma Multicenter surgical outcome benchmarking Immune evasion mechanisms in neuro-oncology Technological innovations in neurosurgical visualization Molecular characterization of rare CNS tumors Professional Contributions: He co-authored the MISEV2023 guidelines for extracellular vesicle studies and participates in international consensus reviews for meningioma classification. His collaborations span institutions across Europe and North America.