Franz Lennard Ricklefs

Prof. Dr. med. Franz Lennard Ricklefs is a Senior Physician and Head of the Working Group at the Department of Neurosurgery, University of Hamburg Faculty of Medicine. He is a Medical Specialist in Neurosurgery with cross-disciplinary expertise in neuro-oncology, molecular pathology, and extracellular vesicle research.

• Affiliations: University Medical Center Hamburg-Eppendorf (UKE), European Liquid Biopsy Society (ELBS), International Consortium on Meningiomas (ICOM)

Research Interests: His work focuses on neurosurgical oncology, particularly glioblastoma and meningioma pathobiology. He investigates DNA methylation patterns, extracellular vesicle biomarkers, and liquid biopsy implementation in clinical neuro-oncology. Additional interests include surgical outcomes for epilepsy and aneurysm management.

Article Trends: Over the last decade, Dr. Ricklefs has published extensively on:

• Extracellular vesicle applications as liquid biopsy markers
• DNA methylation subclasses for glioblastoma and meningioma
• Multicenter surgical outcome benchmarking
• Immune evasion mechanisms in neuro-oncology
• Technological innovations in neurosurgical visualization
• Molecular characterization of rare CNS tumors

Professional Contributions: He co-authored the MISEV2023 guidelines for extracellular vesicle studies and participates in international consensus reviews for meningioma classification. His collaborations span institutions across Europe and North America.