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Ronald DijkmanView profile

Associate Professor

• Respiratory virology
• Coronaviruses
• Influenza viruses
• +5 more

PD Dr. Ronald Dijkman is Group Leader of the Experimental Virology Research Group within the Institute for Infectious Diseases (IFIK) at the University of Bern Medical Faculty. His laboratory is located at the Multidisciplinary Center for Infectious Diseases (MCID) , underscoring his central role in Swiss infectious-disease research infrastructure. Education & Training: While the supplied pages do not list explicit degrees, the title PD Dr. indicates that he has completed a PhD, post-doctoral training, and the Germanic Habilitation, qualifying him as an Associate Professor-level faculty member. Research Focus: Dr. Dijkman’s team investigates host–pathogen interactions in the respiratory epithelium , concentrating on three pillars: Innate immunity triggered by influenza and coronaviruses in human and animal airway epithelial cells. Viral genetic determinants that modulate immune evasion and cross-species transmission. Host determinants that either restrict or facilitate infection across species barriers. To dissect these questions, the group has pioneered genetically-tractable, well-differentiated primary airway epithelial cell (AEC) cultures derived from humans, pigs, cattle and bats, creating a unique comparative platform for zoonotic-risk assessment. Funding & Collaborative Networks: His research is currently supported by: Swiss National Science Foundation (SNF) – project on Molecular characterization of Influenza D virus–host interactions . EU Marie Skłodowska-Curie ITN “HONOURs” – a multi-partner training network on host-switching pathogens and zoonoses. Federal BLV grant – implementation of nanopore sequencing for rapid identification of OIE-notifiable animal viruses. These grants enable a team of one post-doc and four PhD students, together with technical staff. Scientific Output & Impact: Since 2010, Dr. Dijkman has authored >60 peer-reviewed articles. His work on SARS-CoV-2 reverse genetics (Nature, 2020), MERS-CoV receptor usage (Nature, 2014) and single-cell influenza pathogenesis (bioRxiv, 2020–22) has been highly cited, reflecting broad scientific impact. Laboratory & Team: The Experimental Virology group occupies BSL-2 and BSL-3 laboratories equipped with state-of-the-art live-cell imaging, lentiviral genetic engineering, and nanopore sequencing pipelines. The group presently comprises: Larise Oberholster – Early Post-doc Alina Baltensperger – PhD student Jean-Claude Makangara – PhD student Mike Javan Mwanga – PhD student Karen Stevers – PhD student Cinzia Moscardelli – laboratory technician

Fritz E. KühnView profile

Professor

• Organometallic Chemistry
• Medicinal Chemistry
• Molecular Catalysis
• +4 more

Prof. Dr. rer. nat. Fritz E. Kühn is a Professor of Molecular Catalysis at the Department of Chemistry within the TUM School of Natural Sciences at Technische Universität München (TUM). His research spans organometallic chemistry, medicinal chemistry, and molecular catalysis, focusing on carbene ligated metal precursors for task-specific applications in catalysis and biomedical fields. Current research emphasizes oxidation/hydrogenation catalysis with transition metals Active collaborations with industrial partners for small molecule activation Dean of Studies at TUM School of Chemistry since 2016 Spokesperson for TUM Graduate School (Chemistry department) Recent publications highlight advancements in gold(I) NHC complexes for cancer therapy , single-atom rhenium catalysts , and asymmetric epoxidation systems . His work aligns with UN SDGs through sustainable catalytic processes. Scientific recognition includes the Otto Roelen Medal and Hans Fischer Prize . Key research tools include N-heterocyclic carbenes, computational modeling, and industrial process optimization.

• Machine Learning
• Genomics
• Computational Biology
• +5 more

Jian Zhou is an Assistant Professor in the Lyda Hill Department of Bioinformatics at UT Southwestern Medical Center . He holds scholarly positions as a Lupe Murchison Foundation Scholar in Medical Research and CPRIT Scholar . Previously, he was a Flatiron Research Fellow at the Flatiron Institute. Current: Assistant Professor at UTSW Education: B.S. in Biological Sciences (Peking University), Ph.D. in Quantitative and Computational Biology (Princeton University) The Zhou Lab focuses on: Machine learning methods for genomic regulation Deep learning for disease risk prediction Evolutionary analysis of regulatory circuits Single-cell genomic data interpretation Development of biomedical AI tools His research spans genomics , computational biology , and artificial intelligence , with recent articles emphasizing: 3D genome architecture modeling Noncoding variant analysis in disease Single-cell data frameworks Evolutionary regulatory genomics Awards include: Lupe Murchison Foundation Scholar CPRIT Scholar Lab positions available for graduate students , postdoctoral fellows (including remote), data scientists , and undergraduates . The lab provides access to GPU computing clusters at UTSW's South Campus.

Steven LeeView profile

Professor

• Biophysical Chemistry
• Single-Molecule Fluorescence Spectroscopy
• Super-Resolution Imaging
• +5 more

Professor Steven Lee is a leading figure in biophysical chemistry at the University of Cambridge , where he leads the TheLeeLab in the Yusuf Hamied Department of Chemistry . His research focuses on developing advanced single-molecule fluorescence and multidimensional super-resolution imaging techniques to probe fundamental biological processes at unprecedented spatial precision. Developed novel super-resolution microscopy approaches for 2D/3D visualization of T-cell membrane proteins and histone assembly in fission yeast nuclei Pioneer of 15-20nm resolution imaging strategies through fluorophore kinetics and image reconstruction algorithms Recipient of the 2017 Marlow Prize in Physical Chemistry , Lee's lab produces cutting-edge tools with applications in immunology , neurodegeneration , and cellular biophysics . His team maintains active collaborations with Prof Klenerman (FRS MedSci) and Prof Moerner (Nobel Chemistry 2014). Research Highlights : Molecular origins of immunity through T-cell membrane protein interactions 3D histone dynamics during DNA replication/repair Amyloid aggregate quantification for neurodegenerative disease diagnosis Volumetric imaging innovations via vLUME virtual reality platform

Philip RomeroView profile

Associate Professor

• Protein Engineering
• Computational Biology
• Machine Learning
• +3 more

Philip Romero, Ph.D., is an Associate Professor in the Department of Biomedical Engineering at Duke University. He earned his doctorate from the California Institute of Technology in 2012 and leads the Romero Lab, which relocated to Duke in 2023. His research focuses on developing computational and experimental methods for protein engineering, with applications spanning therapeutics, biocatalysis, and synthetic biology. Research Interests: Romero's work integrates machine learning, microfluidics, and high-throughput experimentation to study protein fitness landscapes. Key areas include: Self-driving laboratories for autonomous protein optimization Neural network models for predicting protein functions Therapeutic enzyme engineering (ACE2, caspases, lysins) Microfluidic platforms for deep mutational scanning His recent publications demonstrate a strong emphasis on machine learning-guided protein design, with 80% of post-2022 publications involving AI/ML methods. Therapeutic applications against infectious diseases (particularly SARS-CoV-2) and microbiome engineering represent emerging directions. Lab & Advising: The Romero Lab develops novel technologies for protein engineering, including custom gene library assembly platforms and droplet microfluidics systems. Romero mentors graduate students (e.g., Nishit, who recently defended a thesis on transcription factor engineering) and has collaborated with researchers across computational biology, metabolic engineering, and virology.

Jasmine FooView profile

Professor

• Cancer Evolution
• Mathematical Oncology
• Stochastic Modeling
• +4 more

Jasmine Foo serves as Associate Head and Distinguished McKnight University Professor at the University of Minnesota-Twin Cities' School of Mathematics, holding the Northrop Professorship and co-directing the Therapy Modeling and Design Center. Her leadership spans academic administration and interdisciplinary research initiatives in mathematical oncology. Foo's research pioneers stochastic evolutionary modeling of cancer dynamics, integrating mathematical theory with clinical data to understand tumor initiation, progression, and treatment resistance. Her group focuses on five interconnected themes: plasticity and epigenetics in tumor evolution; drug resistance optimization; data-driven precision oncology; spatial carcinogenesis; and tumor-microenvironment interactions using organoid models. This work bridges probability theory, systems biology, and clinical oncology to develop novel therapeutic strategies. Analysis of her 15 most recent publications reveals a consistent emphasis on quantitative approaches to cancer evolution, with growing integration of machine learning and high-resolution experimental data. Key trends include modeling phenotypic plasticity in resistance development, optimizing dosing schedules using evolutionary principles, and translating spatial tumor dynamics into clinical applications. Scientific recognition includes: Honorable Mention, Feldman Prize for theoretical contributions to tumor evolution modeling Foo actively mentors graduate students and postdoctoral researchers through the School of Mathematics, with research supported by multiple grants (though specific funding sources aren't detailed). Her group maintains strong collaborations with experimental oncology labs and clinical researchers, facilitating data-driven model validation. She co-leads the Therapy Modeling and Design Center and organizes the UMN MathBio Group Meetings, fostering cross-disciplinary collaboration between mathematicians, biologists, and clinicians in cancer research.

Zuri SullivanView profile

Research Fellow

• Immunology
• Neuroscience
• Neuroimmunology
• +5 more

Zuri Sullivan is a postdoctoral researcher at Harvard University, affiliated with the Catherine Dulac Lab. Her work focuses on the intersection of immunology and neuroscience, particularly how inflammatory signals influence social behavior in mice through hypothalamic circuits. Education: PhD in Immunobiology from Yale University AB in Molecular and Cellular Biology (MCB) from Harvard College Research interests span neuroimmunology, inflammation, and genetic screening. Key projects include studying mast cell-leukotriene signaling in anaphylaxis, hypothalamic circuitry in social homeostasis, and the role of γδ T cells in nutrient sensing. Her work often integrates immunobiology with behavioral neuroscience. Recent publications highlight her contributions to understanding immune-gut-brain axis interactions, genetic tools for tissue mapping, and disease mechanisms in obesity-related cancer and tuberculosis. She also develops innovative multimodal screening platforms for in vivo gene function analysis. Scientific Awards: HHMI Hanna H. Gray Postdoctoral Fellowship Zuri actively promotes science communication, diversity in STEM, and education outreach. She previously studied intestinal immune adaptation to diet during her PhD at Yale under Ruslan Medzhitov. Collaborations with William Bishai and Ruslan Medzhitov feature prominently in her research portfolio.

Michael LandsbergView profile

Associate Professor

• Structural Biology
• Cryo-Electron Microscopy
• Microbial Pathogenesis
• +6 more

Dr. Michael Landsberg is an Affiliate Associate Professor at the Institute for Molecular Bioscience and Associate Professor at the School of Chemistry and Molecular Biosciences , University of Queensland . He specializes in single-particle cryo-electron microscopy (cryo-EM) and structural biology , focusing on molecular machines involved in microbial pathogenesis and innate immunity . His research spans from studying bacterial pore-forming toxins to viral infection mechanisms and protein trafficking . Education: BSc (Chemistry), Central Queensland University PhD (Biochemistry), University of Queensland (2003) Research interests include revolutionizing structural biology through cryo-EM to study membrane proteins and multi-component complexes without crystallization. His work on ABC toxins has implications for biopesticides and targeted protein delivery . He also investigates immune signaling pathways (e.g., TIR domains ) and neurodegenerative mechanisms (e.g., SARM1 ). Scientific grants include >$13.5M in competitive funding from Australian Research Council (ARC) and National Health and Medical Research Council (NHMRC) . He supervises PhD students in projects spanning toxin specificity , immune signaling , and virus structures . Key article trends reveal expertise in macromolecular complexes , infectious disease mechanisms , and innovative biotechnological tools . His work bridges structural biology with practical applications in health and agriculture .

Joshua I. GoldView profile

Professor

• Neuroscience
• Computational Neuroscience
• Cognitive Neuroscience
• +6 more

Joshua I. Gold is a Professor of Neuroscience at the Perelman School of Medicine, University of Pennsylvania , where he co-directs the Computational Neuroscience Initiative . His research focuses on the neural mechanisms underlying inference and learning in decision-making, integrating computational modeling with human and non-human primate studies . Education: Sc.B. in Neural Sciences from Brown University (1991), Ph.D. in Neurosciences from Stanford University (1997) Grants: NIH R01 EY015260, NIH F31 MH093099, NIH F21 MH093099 Gold's work explores how uncertainty, contextual information , and neural computations shape adaptive behavior. His lab employs psychophysics, electrophysiology , and pupillometry to study decision-making in dynamic environments. Recent publications highlight Bayesian inference, dual anticipatory processes , and neural correlates of reward prediction . Scientific Contributions: Developed computational models for learning rate regulation Investigated subthalamic nucleus and caudate nucleus roles in decision-making Linked noradrenergic systems to adaptive learning

Paul KingsleyView profile

Academic

• Embryonic Hematopoiesis
• Erythroid Differentiation
• Ontogeny of Hematopoietic Progenitors
• +3 more

Paul Kingsley, Ph.D. is a Research Assistant Professor (Part-Time) in the Department of Pediatrics, Hematology and Oncology at the University of Rochester School of Medicine and Dentistry. His academic credentials include a Ph.D. and M.S. in Developmental Biology from the University of Rochester (1992, 1987) and a B.A. in Biology from Reed College (1982), followed by a Cancer Center Fellowship in Hematopoiesis at the University of Rochester School of Medicine and Dentistry (1992-1994). Dr. Kingsley's research focuses on: Embryonic Hematopoiesis Erythroid Differentiation Ontogeny of Hematopoietic Progenitors Erythroid Precursor Self Renewal His laboratory employs diverse approaches including subtractive hybridization, degenerate PCR, genechip technology (Affymetrix), and in situ hybridization to investigate blood formation in mammalian embryos. His work examines how hematopoiesis initiates in the yolk sac, migrates to the fetal liver, and finally homes to the bone marrow at the end of gestation. Dr. Kingsley's publication record demonstrates consistent focus on molecular mechanisms of blood cell development, with recent work emphasizing erythroid maturation, hematopoietic stem cell regulation, and chromatin dynamics during erythropoiesis. His research spans from fundamental developmental biology to potential clinical applications in blood disorders and radiation protection. Key research contributions include: Mechanisms of erythroblast enucleation and maturation Regulation of hematopoietic stem cell specification and migration Chromatin remodeling during late-stage erythropoiesis Mitochondrial iron metabolism in heme synthesis Developmental origins of immune cell lineages Effects of radiation on hematopoietic recovery Dr. Kingsley has maintained a productive research career with extensive collaboration, particularly with Dr. James Palis, resulting in numerous high-impact publications in journals such as Nature, Science, Blood, and The EMBO Journal.

• Epigenetics
• Genomic Integrity
• Aging and Longevity
• +7 more

Jessica Tyler is a Professor in the Department of Pathology and Laboratory Medicine at Weill Cornell Medicine, where she also holds affiliations with the Graduate School of Medical Sciences. She leads the Laboratory of Epigenetics and Genomic Integrity, conducting cutting-edge research on chromatin dynamics, DNA repair, and aging using budding yeast and human cell models. PhD, Molecular Virology, University of Glasgow (1994) Bachelor’s Degree, Biochemistry, University of Sheffield (1990) Postdoctoral Training, UCSD under Jim Kadonaga Former Faculty: University of Colorado School of Medicine, MD Anderson Cancer Center Dr. Tyler’s research focuses on epigenetics, genomic integrity, and longevity , particularly how chromatin structure regulates DNA repair, gene expression, and aging. She investigates conserved mechanisms using yeast genetics, biochemistry, and genome-wide analyses. Her lab discovered that histone depletion occurs during aging and that overexpression of histones extends lifespan. They also pioneered studies on the tardigrade Dsup protein, showing it protects chromatin and enhances longevity in yeast. The recent publications reflect a strong focus on DNA double-strand break repair, chromatin assembly, histone chaperones (e.g., CAF-1, ASF1), and aging . Work spans from mechanistic biochemistry to systems-level genomics, often linking chromatin dynamics to disease processes like cancer and neurodegeneration. Technologies include CRISPR, microfluidics, proximity ligation, and high-resolution sequencing. Fellow of the American Association for the Advancement of Science (AAAS), 2017 National Academy of Sciences Kavli Fellow, 2011 University of Glasgow Tenovus Medal, 2010 AACR Woman in Cancer Research Charlotte Friend Memorial Award, 2009 Dean’s Mentor of the Year, 2009 Faculty Educator of the Month, 2015 Dr. Tyler has mentored numerous graduate students and postdoctoral fellows, many of whom now hold faculty or industry positions. She is Principal Investigator on multiple NIH-funded grants exploring chromatin’s role in DNA repair and aging. Her lab actively welcomes rotation and graduate students. The Tyler Lab is located at Weill Cornell Medicine, 1300 York Avenue, New York, NY.

Petter BrodinView profile

Professor

• Systems Immunology
• Pediatric Immunology
• Immune System Regulation
• +7 more

Petter Brodin is a dual-appointed academic with a Professor ship at Karolinska Institutet 's Department of Women's and Children's Health and a Senior Lecturer position at Imperial College London 's MRC London Institute of Medical Sciences. His work bridges clinical pediatrics and cutting-edge systems immunology , focusing on human immune system profiling through blood analysis. Education : MD/PhD from Karolinska Institutet, postdoc at Stanford University Research spans three major domains: Sex hormone immunomodulation - Revealing testosterone's role in suppressing autoimmune pathways while enhancing infection vulnerability through Nature studies of gender-affirming treatment Post-COVID pathophysiology - Developing antiviral treatment strategies for chronic SARS-CoV-2 reservoirs with Pfizer, focusing on severely affected patients Developmental immunology - Mapping immune-microbiome interactions in newborns and cancer immunotherapy applications in pediatric solid tumors Major awards include: 2023 Oscar Medin Prize 2024 Wallenberg Scholar 2022 VR and SSMF Consolidator Awards 2019 EMBO Young Investigator 2015 ERC Starting Grant Supervised 5 PhD/MSc students while leading a multidisciplinary team at BrodiN lab (brodinlab.com). Current clinical trials include: 15-day antiviral regimen for tissue reservoirs Immunomodulatory approaches for autoimmune profiles Active in science communication through BlueSky platform and Paris Kids Cancer Symposium leadership, emphasizing human-centric research over animal models.

June Helen MyklebustView profile

Associate Professor

• B-cell lymphoma
• Cancer immunology
• Tumor microenvironment
• +7 more

June Helen Myklebust is an Associate Professor at the Institute for Cancer Research, Faculty of Medicine, University of Oslo. Her research focuses on B-cell lymphoma, cancer immunology, and tumor microenvironment with particular emphasis on B-cell receptor signaling and germinal center biology. She maintains a strong research presence at Oslo University Hospital Radiumhospitalet where she conducts laboratory research and collaborates with clinical teams. Dr. Myklebust's primary research interests include: Mechanisms of B-cell receptor signaling in lymphoma Tumor microenvironment and immune interactions in B-cell malignancies Development of novel immunotherapies including CAR T-cell approaches Genomic and molecular characterization of lymphoma subtypes Understanding mechanisms of transformation in indolent lymphomas Analysis of her recent publications reveals a strong focus on translational cancer research with emphasis on B-cell lymphoma biology. Her work spans from basic molecular mechanisms of B-cell signaling to clinical applications of immunotherapy. A significant portion of her research investigates how tumor cells interact with the immune system, particularly focusing on T cell exhaustion and regulatory mechanisms within the tumor microenvironment. Her laboratory employs advanced techniques including single-cell profiling, mass cytometry, and genomic analysis to understand lymphoma heterogeneity and evolution. Dr. Myklebust maintains an active research program with numerous collaborations both nationally and internationally. Her work has appeared in high-impact journals including Blood, Cancer Cell, and Nature family journals, demonstrating the significance of her contributions to the field of lymphoma research. She is actively involved in mentoring researchers and collaborating with clinical teams to translate basic research findings into potential therapeutic approaches for lymphoma patients. Her laboratory work focuses on understanding the molecular mechanisms driving lymphomagenesis and identifying novel therapeutic targets.

Thomas MarescaView profile

Associate Professor

• Cell Biology
• Molecular Biology
• Chromosome Segregation
• +3 more

Thomas Maresca is an Associate Professor in the Biology Department at the University of Massachusetts Amherst, serving as Graduate Program Director for Molecular & Cellular Biology within the Interdisciplinary Doctoral Graduate Program (IDGP). His research laboratory investigates fundamental mechanisms of cell division with institutional affiliation to the university's life sciences division. His academic training includes: Ph.D. in Cell Biology from the University of California at Berkeley (2005) B.S. in Biology from the University of North Carolina at Chapel Hill (1999) Dr. Maresca's research centers on chromosome segregation mechanics during mitosis, employing Drosophila and Xenopus model systems with advanced live-cell imaging techniques. His laboratory specializes in quantifying kinetochore-microtubule interactions , error correction mechanisms , and force generation during cell division. Key approaches include FLIM-FRET biosensors, single-molecule tracking, and micromanipulation in egg extracts to dissect how intrinsically disordered proteins, motor complexes (particularly dynein), and kinase networks (Aurora A/B, MPS1) ensure mitotic fidelity. Current work focuses on spatiotemporal regulation of phosphorylation gradients and mechanical feedback at the kinetochore-microtubule interface. Analysis of his 15 most recent publications reveals a consistent trajectory in mitotic mechanics with increasing emphasis on intrinsically disordered proteins as mechanical regulators and subcellular signaling hubs . His work bridges molecular biophysics with cellular function, demonstrating how microtubule plus-ends act as physical signaling platforms and how kinase crosstalk establishes precise spatiotemporal control during anaphase. Recent methodological innovations include commercial FLIM-FRET adaptation and quantitative force measurements at kinetochores. As Graduate Program Director, Dr. Maresca oversees curriculum development and student mentorship for the Molecular & Cellular Biology track. His laboratory (located in Morrill Science Center IV, Room 436) maintains active research programs in kinetochore mechanics and mitotic regulation, supported by continuous publication output since 2000. Collaborative networks include structural biologists and biophysicists investigating mechanochemical transduction in division processes.

• Genetic Kidney Diseases
• Chronic Kidney Disease
• Autosomal Dominant Polycystic Kidney Disease (ADPKD)
• +3 more

Gabriel Loeb, MD, PhD is an Assistant Professor at the University of California, San Francisco (UCSF) School of Medicine , where he operates as a physician-scientist specializing in genetic kidney diseases . His research integrates human genetics , genomics , and novel kidney disease models to identify molecular mechanisms in chronic kidney disease and Autosomal Dominant Polycystic Kidney Disease (ADPKD). Clinically, he focuses on familial and genetic kidney disease care at the UCSF Nephrology Faculty Practice . Education BS in Biology (2005), Stanford University MD (2015), Cornell PhD in Immunology (2015), Cornell/Rockefeller/Sloan Kettering Internal Medicine Residency (2018), Brigham and Women's Hospital/Harvard Medical School Nephrology Fellowship (2021), UCSF Research Interests center on leveraging human genetic variation to decode kidney disease mechanisms, with a focus on ADPKD and tubule epithelial regulatory elements . His work explores cell type-specific genomics , polycystin channel function , and urine multiomics for non-invasive diagnostics. Recent Publications highlight advancements in ADPKD mechanistic understanding , urine-based liquid biopsies , and genomic deep learning model limitations . Key journals include Nature Genetics , Nature Communications , and bioRxiv . Grants & Programs Laboratory for Genomics Research Innovation Award (2024–2025) Physician Scientist Scholars Program, UCSF (2021–2026)