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Dr. Anne Conibear is an Honorary Research Fellow at the School of Biomedical Sciences , University of Queensland . Her research focuses on understanding the role of post-translational modifications (PTMs) in regulating protein structure and function using chemical synthesis , NMR spectroscopy , and protein semi-synthesis techniques. PhD in Chemistry/Biochemistry, University of Queensland Postdoctoral fellowship in Vienna Current UQ Development Fellowship for independent research Her work leverages chemical biology tools to study PTMs like phosphorylation, sulfation, and palmitoylation, providing atomic-resolution insights into how cells dynamically respond to environmental cues. Recent publications highlight structural analysis of PTMs in Hsp90 , HMGN1 , and CD44 , alongside methodological advances in isotope labeling and ligation techniques . She has also contributed to venom peptide research and antimicrobial mechanisms . 2022: Australian Peptide Display Facility (ARC LIEF) 2020-2021: UQ Early Career Researcher Grant 2019-2022: CIL Research Grant 2019-2021: UQ Development Fellowship Dr. Conibear collaborates with industry partners like Syntab Therapeutics and CIL Research Program , while supervising research projects such as the 2024 Master Philosophy thesis on µ-Conotoxins . She actively participates in scientific outreach, including INDICAR cancer research initiatives .

• Chemical Biology
• Protein Structure and Function
• Peptide Chemistry
• +3 more

Chad Borges is an Associate Professor at Arizona State University (ASU) with joint appointments in the School of Molecular Sciences and the Biodesign Institute , specifically its Piper Center for Personalized Diagnostics. His work bridges analytical chemistry, biochemistry, and biospecimen science, with a focus on developing innovative techniques for glycan and protein posttranslational modification (PTM) analysis. He serves as a Health Solutions Ambassador for ASU’s College of Health Solutions. Education: Ph.D. in Analytical Toxicology, University of Utah (2001) B.S. in Chemistry, Walla Walla College (1997) Research Interests: Dr. Borges’ research centers on glycan node analysis for bottom-up glycomics, quantifying PTMs (e.g., oxidation, glycation) as disease or sample integrity markers, and designing time-temperature indicators for biospecimen preservation. His lab develops methods to detect artifactual molecular changes in clinical samples, such as S-cysteinylated albumin (ΔS-Cys-Albumin), which reveals thawed-state exposure. He also explores glycan alterations in extracellular vesicles and their role in cancer progression. Article Trends: His recent publications emphasize glycan node analysis for cancer diagnostics (lung, bladder), biospecimen integrity assessment via PTMs, and novel analytical methods using mass spectrometry. Collaborative studies with Mayo Clinic and others highlight glycan features as prognostic tools and the impact of storage conditions on clinical research reliability. Scientific Recognition: His 2019 tenure and promotion to Associate Professor at ASU underscore his contributions. Students in his lab have received awards such as the John Kacoyannakis Award (for analytical chemistry excellence) and the Royal Society of Chemistry Certificate of Excellence . Teaching & Advising: Dr. Borges mentors students in analytical chemistry and biochemistry, with recent advisees earning PhDs and Master’s degrees. His courses include Analytical Chemistry (CHM 325) and Research Techniques (BCH 392). Labs & Collaborations: The Borges Lab collaborates with the Mayo Clinic and operates at the Biodesign Institute . They are commercializing visual time-temperature indicators through CryoVeritas, Inc. , an ASU spin-off.

• Protein Posttranslational Modifications
• Glycomics
• Biospecimen Integrity
• +4 more

Katherine Albanese is an Assistant Professor at Wake Forest University's Department of Chemistry. She leads the Albanese Lab, focusing on epigenetic pathways and developing novel therapeutic targets through protein design, chemical biology, and synthetic biology approaches. Her research integrates computational protein design, histone posttranslational modification (PTM) analysis, and synthetic cell systems to study gene regulation and epigenetic mechanisms. Education: BS in Chemistry (2016, Wake Forest University); PhD in Chemistry (2021, UNC Chapel Hill); Postdoctoral Researcher (2021-2024, University of Bristol, UK). Research Interests: Histone PTM dynamics, de novo protein design, synthetic cell models, oncogenic histone mutations, and combinatorial histone codes. Her lab employs a multi-disciplinary approach combining biochemistry, computational modeling, and synthetic biology to address fundamental questions in epigenetics. Key Research Areas: (1) New histone PTM discovery, (2) Aberrant histone mutations in cancer, (3) Synthetic cell platforms for epigenetic hypothesis testing. Recent work highlights engineered reader proteins, charge-agnostic binding mechanisms, and α-helical barrel design for therapeutic applications. Lab Website: albaneselab.com

• Histone Posttranslational Modifications
• Protein Design
• Chemical Biology
• +3 more

Dr. Chuna Ram Choudhary is a Professor and Group Leader at the Novo Nordisk Foundation Center for Protein Research (CPR) within the Faculty of Health and Medical Sciences at the University of Copenhagen , Denmark. His academic journey includes a PhD in Biochemistry (University of Münster, Germany, 2001–2006) and postdoctoral training at the Max Planck Institute for Biochemistry (2007–2009). He leads a research group focused on protein posttranslational modifications (PTMs) —particularly lysine acetylation and ubiquitylation —using quantitative mass spectrometry to map their roles in cell signaling networks and DNA repair . Research interests center on systems-wide analysis of PTMs, emphasizing their dynamic regulation of protein activity, stability, and localization in health and disease. His lab has pioneered methods for site-resolved acetylation stoichiometry and ubiquitylation dynamics , revealing connections between metabolism , transcription , and genome integrity . Collaborations span national and international institutions , including groups at CPR and beyond. Research output trends show a focus on ubiquitin and acetylation signaling , DNA repair mechanisms , and enhancer-promoter compatibility . His work has significant implications for cancer biology , cardiovascular diseases , and developmental processes . Scientific awards include: 2015: ERC Consolidator Grant 2014: Junior Researcher Prize (Danish Cancer Society) 2014: Hallas Møller Investigator Grant (NNF) 2013: EMBO Young Investigator 2012: Sapere Aude Grant (Danish Research Council) 2009: Artur Pappenheim Prize (German Society of Hematology and Oncology) Lab activities involve cutting-edge proteomics and mass spectrometry , with a strong emphasis on translational research and therapeutic target identification .

• Protein Post-Translational Modifications
• Cell Signaling Networks
• Proteomics
• +5 more

TuKiet Lam is a Research Scientist and Director of the Keck MS & Proteomics Resource at Yale School of Medicine's Department of Molecular Biophysics and Biochemistry. He specializes in mass spectrometry (MS) and proteomics, providing advanced instrumentation and analyses for interdisciplinary research in biological, clinical, and pharmaceutical fields. His career includes leadership roles at the National High Magnetic Field Laboratory and Florida State University. Education: BS in Chemistry, Rollins College (1998) PhD in Analytical Chemistry, Florida State University (2002) Postdoctoral Training at National High Magnetic Field Laboratory (2003) Research Focus: Dr. Lam’s work focuses on applying high-resolution mass spectrometry to study protein interactions, posttranslational modifications, and biomarkers in diseases like Alzheimer’s, cancer, and cardiovascular disorders. His lab collaborates widely, contributing to over 125 publications. Key Projects: Proteomic profiling of Alzheimer’s axonal pathology Cerebrospinal fluid biomarker discovery for neurodegenerative diseases Metabolite analysis in preterm birth and diabetes Drug metabolism and cannabinoid effects on brain proteomes Labs & Resources: Director of the Keck MS & Proteomics Resource, a core facility supporting Yale researchers with state-of-the-art MS technologies. The lab emphasizes reproducible methodologies for protein quantitation, PTM analysis, and small molecule characterization.

• Mass Spectrometry
• Proteomics
• Metabolomics
• +12 more

Eva Ge is an Assistant Professor in the Department of Chemistry at the Klein College of Science, University of North Carolina at Charlotte. Her research explores the intersection of bioinorganic chemistry, chemical biology, and enzymology, focusing on modified proteins and their interactions with metal ions in disease contexts. Education: B.A. in Chemistry and Chemical Biology from Cornell University, Ph.D. in Chemistry from Princeton University, Postdoctoral training at UC Berkeley. Her work investigates covalent protein posttranslational modifications (PTMs) and their crosstalk with metal binding, particularly in relation to cancer and neurodegenerative diseases. The Ge group integrates peptide chemistry, enzymology, and cell biology in their studies. Recent research highlights include the development of RNA nanoparticles for targeted therapies in triple-negative breast cancer (2023), aligning with broader trends in nanotechnology and precision oncology. This work underscores her focus on chemical biology applications in human health. The Ge group operates at the University of North Carolina at Charlotte, utilizing interdisciplinary methods such as air-free biochemistry and cell-based assays to address fundamental questions in protein chemistry.

• Bioinorganic chemistry
• Chemical biology
• Peptide and protein chemistry
• +1 more

Dr. Yue Chen is an Associate Professor in the Department of Biochemistry, Molecular Biology and Biophysics at the University of Minnesota's College of Biological Sciences. His research focuses on discovering novel posttranslational modification (PTM) pathways involved in protein homeostasis, cellular signaling, and epigenetic regulation using mass spectrometry-based proteomics, chemical biology, and bioinformatics. Ph.D. from University of Texas at Arlington Postdoctoral training at University of Chicago Research Interests include: Quantitative chemical proteomics for lysine modification pathways Environmental impacts on PTM networks in cancer and metabolic diseases Development of stoichiometry analysis tools for ubiquitination and acetylation Epigenetic reprogramming via histone modifications Publications highlight his lab's innovations in crosslinking interactome analysis, constitutional isomer profiling, and hypoxia signaling. Awards include the NSF CAREER and NIH R35 MIRA grants, as well as HHMI Fellowships for inclusive excellence. His team includes graduate students and postdoctoral fellows working on cancer models, metabolic diseases, and environmental toxicology projects.

• Proteomics
• Posttranslational Modifications
• Epigenetics
• +7 more

Simone Sidoli, Ph.D., is an Assistant Professor in both the Department of Biochemistry and the Department of Genetics at Albert Einstein College of Medicine. His research focuses on chromatin dynamics, histone modifications, and their roles in disease development. He employs advanced mass spectrometry techniques and 3D cell culture models to study how epigenetic mechanisms regulate cellular identity and contribute to pathological states. His work integrates proteomics and chromatin biology to uncover how histone post-translational modifications (PTMs) influence chromatin structure and function. Key areas of investigation include the biological consequences of aberrant chromatin states in cancer, metabolic disorders, and viral infections. Dr. Sidoli's methodological innovations aim to bridge gaps between molecular mechanisms and disease outcomes. Recent publications highlight his contributions to understanding histone reader interactions, SUMOylation in HIV pathogenesis, and myocardial proteomic changes in heart failure. His interdisciplinary approach combines biochemical assays, computational analysis, and cutting-edge imaging to dissect epigenetic regulation at multiple scales.

• Chromatin Biology
• Proteomics
• Mass Spectrometry
• +3 more

Dr. Kalesh Karunakaran is a Senior Lecturer in Chemistry at Teesside University's School of Health & Life Sciences, leading the BSc (Hons) Pharmaceutical Science Course. His research focuses on chemical proteomics, particularly posttranslational modifications (PTMs) and their role in diseases like cancer and neglected tropical diseases (e.g., leishmaniasis). He holds a PhD from the National University of Singapore and has held postdoctoral positions at Imperial College London and Durham University. Education: PhD in Chemical Biology (National University of Singapore, 2010) MSc in Chemistry (Indian Institute of Technology Madras, 2004) Bachelor's in Chemistry (Mahatma Gandhi University, 2002) Research Interests: Development of chemical probes for protein function analysis PTM dysregulation in cancer and parasitic diseases Heat shock protein biology and inhibitor design Proteomic methodologies (e.g., activity-based proteomics, quantitative mass spectrometry) Awards & Grants: Marie Curie Individual Fellowship (2012–2014) MRC-GCRF Grant (~£230,000 for Leishmania research) Royal Society Research Grant Associate Editor, Frontiers in Pharmacology Labs & Collaborations: Leads a multidisciplinary lab integrating chemical synthesis, proteomics, and bioinformatics. Collaborates with groups at Imperial College London, Institute of Cancer Research, and global institutions on infectious disease research.

• Chemical Proteomics
• Posttranslational Modifications (PTMs)
• Drug Discovery
• +4 more

Dr. Saiful M Chowdhury is an Associate Professor in the Department of Chemistry and Biochemistry at the University of Texas at Arlington. He has over 15 years of experience in proteomics and bioanalytical mass spectrometry, focusing on method development for protein interaction mapping and posttranslational modification analysis. Joined UTA in 2012 PhD in Analytical Chemistry (Washington State University, 2006) Postdoctoral training at Pacific Northwest National Laboratory and NIH His research targets lipid raft proteomics and Toll-like receptor signaling in environmental diseases like atherosclerosis and sepsis, utilizing novel cross-linking and chemical labeling strategies. Collaborative applications include studying host-pathogen interactions and innate immunity. Recent projects include 2025 publications on viral/allergenic protein binding domains, tyrosine residue labeling, and intersubunit communication in oxidoreductases. Over 15 high-impact articles since 2015, with methodological innovations in cross-linking and PTM characterization. Awards include the College of Science Innovation Grant (2024), Bangladesh Council Keynote (2024), Emerging Investigator (JASMS, 2017), and NIH FARE Fellowship (2012). He has supervised multiple PhD and Master's students , including Ryan Burk and Zixiang Fang, and teaches courses in quantitative chemistry, mass spectrometry, and analytical instrumentation. Active in grant reviewing , workshop organization, and data science committees.

• Proteomics
• Mass Spectrometry
• Protein-Protein Interactions
• +3 more

Wenshe Ray Liu, PhD is a distinguished academic and researcher at Texas A&M University, holding the titles of Presidential Impact Fellow and Gradipore Endowed Chair in Chemistry . He serves as a Professor in the Department of Chemistry and Biochemistry and Biophysics, with dual appointments in both disciplines. His research spans epigenetic chromatin regulation and drug development targeting epigenetic proteins. Education : B.S. in Chemistry, Peking University (2000) PhD in Chemistry, University of California, Davis (2005) Postdoctoral Researcher at The Scripps Research Institute (2005–2007) Research Interests : Epigenetic regulation via histone posttranslational modifications (PTMs) Development of therapeutics targeting chromatin-modifying enzymes (SIRT1-3, HDACs, LSD1-2, ENL, BRD9) Chemical biology tools for chromatin assembly and analysis Phage display technologies for peptide library diversification His lab operates two core units: a biological unit focusing on chromatin structure-function studies and a chemical unit developing novel inhibitors and drug candidates. Grants & Awards : Presidential Impact Fellow (2018) ACS Chemical Biology Most Prolific Author (2017) NSF Career Award (2012) Molecular BioSystems Emerging Investigator (2010) Lab & Collaborations : Leverages cryo-EM, proteomics, and synthetic chemistry for structural and functional studies Active in SARS-CoV-2 main protease inhibitor discovery Develops genetic code expansion tools for site-specific protein modification

• Epigenetic Chromatin Regulation
• Histone Modifications
• Therapeutic Drug Development
• +3 more

Matthew Robert Pratt is a Professor of Chemistry at the University of Southern California (USC), affiliated with the USC Michelson Center for Convergent Bioscience since joining the faculty in 2009. His research laboratory develops chemical tools to investigate fundamental biological processes. Education: B.S. in Biochemistry and Mathematics, University of Arizona (1999) Ph.D. in Chemistry, University of California, Berkeley (2004) Research Interests: Professor Pratt specializes in chemical biology approaches to posttranslational modifications (PTMs) , particularly O-GlcNAc glycosylation and ubiquitination . His lab creates bioorthogonal chemical reporters and synthetic proteins to study how PTMs regulate cellular responses to metabolic stress and contribute to diseases like cancer and neurodegeneration. This interdisciplinary work integrates organic synthesis , protein biochemistry , and cellular biology to decode molecular mechanisms in living systems. Scientific Awards: American Cancer Society Postdoctoral Fellowship Advising and Grants: Professor Pratt mentors graduate students through USC's Chemistry PhD program and recruits postdoctoral researchers directly. His laboratory operations are supported by research grants enabling chemical tool development for PTM analysis. Prospective postdocs must submit cover letters, CVs, and research summaries for consideration. Lab and Team: The Pratt Lab operates within the USC Michelson Center for Convergent Bioscience (1002 West Childs Way, MCB 114), employing multidisciplinary teams to investigate PTM roles in disease pathways through organic synthesis, genetic engineering, and cellular assays.

• Chemical Biology
• Posttranslational Modifications
• Glycosylation
• +7 more