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Thibault Mayor is a Professor in the Department of Biochemistry and Molecular Biology and the Michael Smith Laboratories at the University of British Columbia (Vancouver). His research focuses on understanding how cells manage misfolded proteins, with implications for neurodegenerative diseases like Parkinson's and Alzheimer's. He holds academic affiliations with the Centre for High-Throughput Biology (CHiBi) and has been recognized with awards including the UBC Killam Teaching Award (2020). Education: BSc, University of Geneva, Switzerland (1997) PhD, University of Geneva & Max Planck Institute of Biochemistry, Germany (2001) Postdoctoral Fellow, California Institute of Technology (2002) Research Interests: Mayor's lab investigates protein homeostasis, ubiquitin-proteasome system dynamics, and the molecular mechanisms underlying protein aggregation in aging and disease. Projects include proteomic approaches to identify aggregation-prone proteins and develop microbial cell factories for protein production. Grants & Awards: CIHR Project Grant ($730K, 2018) Michael Smith Foundation Career Award (2012) UBC Killam Teaching Award (2020) Labs & Collaborations: The Mayor Lab is part of the Michael Smith Laboratories and collaborates with computational biologists like Jörg Gsponer. They maintain active partnerships in proteomics and systems biology, contributing to initiatives like the BC Proteomics Network.

• Protein Homeostasis
• Ubiquitin Proteasome System
• Neurodegenerative Diseases
• +7 more

Christopher M. Overall is a Full Professor at the University of British Columbia in the Faculty of Dentistry, Department of Oral Biological and Medical Sciences . He is also a Principal Scientist at the Centre for Blood Research and holds associate memberships in UBC's Biochemistry & Molecular Biology , Obstetrics and Gynecology , and Bioinformatics Graduate Program departments. As a Canada Research Chair Laureate , he pioneered the field of degradomics to study proteases in vivo. B.D.S., University of Adelaide Ph.D., University of Toronto Postdoctoral Fellowship, UBC (with Nobel Laureate Michael Smith) Dr. Overall’s research focuses on protease proteomics and systems biology , particularly degradomics to analyze protease substrates in diseases like COVID-19 and immunodeficiency . His work on matrix metalloproteinases has revealed new therapeutic strategies for inflammatory diseases and cancer . His 15 most recent articles (2015–2008) demonstrate expertise in TAILS proteomics , protein terminomics , and protease network analysis with applications in arthritis , antiviral immunity , and precision medicine . Scientific Awards 2022 Helmut Holzer Award 2018 Royal Society of Canada Fellow 2014 Tony Pawson Canadian Proteomics Award 2013 IADR Distinguished Scientist Award Dr. Overall has mentored 61 trainees , including 9 full professors with department chairs, and received the UBC John McNeill Mentorship Award (2023). He leads the HUPO Chromosome-centric Human Proteome Project and consults for Genentech and Novartis .

• Protease Proteomics
• Systems Biology
• Degradomics
• +6 more

Dr. Jacques Archambault is a Professor in the Department of Microbiology and Immunology at McGill University , and an associate member of the Division of Experimental Medicine since 2016. His research focuses on the molecular biology and pathogenesis of human papillomaviruses (HPVs) and polyomaviruses (HPyVs), with an emphasis on their replication mechanisms as episomes in host cells. The Archambault laboratory employs functional genomics, proteomics, and chemical biology approaches to identify cellular pathways exploited by these viruses and develop high-throughput assays for screening small molecule inhibitors of viral replication. Analysis of his recent publications reveals a strong focus on HPV and HPyV replication machinery, including studies on the E1 helicase, UAF1-USP1 interactions, and structural characterization of viral proteins involved in DNA replication. His work bridges virology, oncology, and drug discovery, particularly targeting oncogenic HPV types implicated in anogenital and oropharyngeal cancers, as well as HPyVs like BKPyV and JCPyV that cause pathologies in immunosuppressed patients. Current efforts in the lab aim to elucidate the molecular mechanisms by which HPVs and HPyVs replicate their genomes and to develop antiviral therapies targeting these processes. Techniques such as fluorescence anisotropy, NMR spectroscopy, and crystallography are frequently employed to study protein-DNA and protein-protein interactions critical to viral replication.

• Human Papillomavirus (HPV)
• Polyomavirus
• Viral DNA Replication
• +4 more

Christopher Lawson is an Assistant Professor in the Department of Chemical Engineering and Applied Chemistry at the University of Toronto, affiliated with the Faculty of Applied Science and Engineering. He serves as Principal Investigator of the Microbiome Engineering Lab and is part of BioZone – the Centre for Applied Bioscience and Bioengineering. His research focuses on engineering anaerobic microbiomes for resource recovery from waste streams using systems biology, synthetic biology, and machine learning approaches. B.A.Sc., M.A.Sc. (University of British Columbia) Ph.D. (University of Wisconsin-Madison) Postdoctoral Training (Berkeley Lab) Lawson's work addresses the challenge of controlling complex microbial interactions in engineered systems to enable scalable biotechnologies for renewable energy, chemicals, and materials. His lab develops high-throughput methods integrating automation and computational tools to optimize microbiome assembly and metabolic fluxes. Recent publications highlight advancements in metabolic modeling , isotope tracing , and systems-level analysis of anaerobic microbiomes, with applications in wastewater treatment , anammox granules , and bioenergy production . His research bridges fundamental microbiology with industrial-scale bioprocess engineering. Scientific Awards ISME/IWA BioCluster Rising Star Award (2022) Jacobs Engineering Group/AEESP Outstanding Doctoral Dissertation Award (2020) Wesley Eckenfelder Graduate Research Award (2019) WEF Canham Graduate Studies Scholarship (2018) NSERC Post-Graduate Scholarship – Doctoral (2014) Lawson actively mentors students and postdocs, emphasizing technical rigor, communication skills, and independence. His lab collaborates within BioZone and with industry partners to advance "team science" principles. Current projects focus on creating engineered microbiomes for commercial-scale waste valorization.

• Microbiome Engineering
• Systems Biology
• Synthetic Biology
• +5 more

Dr. John Rohde is an Associate Professor in the Department of Microbiology & Immunology at Dalhousie University's Faculty of Medicine. His research focuses on understanding mechanisms of bacterial pathogenesis, particularly how Shigella spp. exploits host cell systems. He holds a PhD in Biochemistry from the University of British Columbia and completed postdoctoral training at Duke University, Institut Pasteur, and Mount Sinai Hospital's Samuel Lunenfeld Research Institute. His lab develops genetic tools to study bacterial virulence at systems levels. Education: BS/MS in Bacteriology (University of Idaho), PhD in Biochemistry (UBC) Research Interests: Shigella pathogenesis, ubiquitin ligases, type III secretion systems Recent work includes studies on Shigella's manipulation of host actin via RACK1 and the role of ubiquitin in pathogen survival. He collaborates internationally on projects combining proteomics and immunology to uncover antimicrobial defense mechanisms.

• Bacteriology
• Microbial Pathogenesis
• Inflammation
• +4 more

Julian Guttman is a Professor in the Department of Biological Sciences at Simon Fraser University (SFU), specializing in Cellular Microbiology. He serves as Editor-in-Chief of the journal Cytoskeleton . His research focuses on bacterial infections' molecular mechanisms, particularly how pathogens like Listeria monocytogenes , E. coli , and Salmonella manipulate host cell cytoskeletons (actin, microtubules) to invade, spread, and cause disease. Key areas include actin-based motility, pathogen-induced membrane protrusions, and therapeutic development. His lab actively recruits undergraduate, graduate students, and postdoctoral fellows. Education: BSc (University of Western Ontario), MSc and PhD (University of British Columbia). He has published extensively on host-pathogen interactions, with recent work on Listeria's caveolin-mediated spreading, KATNAL1-driven microtubule disassembly by Klebsiella, and cyclophilin A's role in Salmonella invasion. His work bridges microbiology, cell biology, and structural biology to combat infectious diseases.

• Cellular Microbiology
• Bacterial Pathogenesis
• Cytoskeleton Alterations
• +3 more

R. Glen Uhrig, PhD, is an Associate Professor of Plant Biology at the University of Alberta within the Department of Biological Sciences, Faculty of Science. His research focuses on plant functional genomics and proteomics, particularly examining diurnal regulation of cellular processes via quantitative proteomics in Arabidopsis thaliana and agriculturally relevant crops. The Uhrig Lab investigates post-translational modifications (PTMs) such as phosphorylation and acetylation to understand plant adaptation to environmental changes. Educationally, he holds a B.Sc.H. (2005) and M.Sc. (2008) from Queen’s University, followed by a Ph.D. from the University of Calgary (2013). His postdoctoral training at the Swiss Federal Institute of Technology (2017) furthered his expertise in plant systems biology. R. Glen Uhrig teaches courses including BIOL 343/543 (Macromolecular Characterization Techniques) and BOT 380 (Drug Plants), emphasizing hands-on proteomics and plant biotechnology. His awards include the ASTech Award (2022), NSERC Post-Doctoral Award (2015–2017), and the Marie Curie Plant Fellowship (2013–2015). His work bridges fundamental research with applications in agri-food production and crop resilience. Key research themes include: 1) Diurnal regulation of plant proteomes and PTMs, 2) Molecular mechanisms of plant immunity and stress responses, and 3) Leveraging proteomics to enhance crop productivity. The lab employs cutting-edge tools like quantitative mass spectrometry and multi-omics integration to address these questions.

• Plant Functional Genomics
• Quantitative Proteomics
• Post-Translational Modifications
• +4 more

Adetola B. Adesida serves as a full Professor in the Department of Surgery within the Faculty of Medicine & Dentistry at the University of Alberta . His laboratory focuses on developing autologous cell-based tissue engineering strategies for cartilage and meniscus repair, leveraging interdisciplinary collaborations between chemists, biologists, clinicians, and material scientists. PhD in Pharmacy, Victoria University of Manchester (1999) Postdoctoral Research, Wellcome Trust Centre for Cell-Matrix Research Dual Fellowship, Harvard University/Massachusetts General Hospital (2006) Marie-Curie Fellowship, European Commission (2007) Dr. Adesida's research centers on stem cell biology and tissue engineering for musculoskeletal regeneration, with emphasis on: Meniscus and articular cartilage repair mechanisms Stem cell-chondrocyte interactions in 3D microenvironments Bioreactor conditioning (hypoxia, dynamic compression) Sex-specific responses in knee osteoarthritis models Space-related microgravity effects on joint tissues His work bridges fundamental mechanobiology with clinical translation through industry partnerships like CellCoTec. Recent publications demonstrate a strong trend toward 3D bioprinting of nasal and meniscal tissues, sex-dimorphic responses in osteoarthritis, and space medicine applications . Key themes include bioink development, molecular characterization of fibrochondrocytes, and prevention of post-traumatic joint degeneration through regenerative strategies. CIHR Research Award (2013) Harvard University/Massachusetts General Hospital Fellowship (2006) European Commission Marie-Curie Fellowship (2007) Dr. Adesida leads the Orthopaedic Tissue Engineering Laboratory , directing multiple CIHR-funded projects on meniscus regeneration using mesenchymal stem cells. His research integrates advanced bioreactor systems for mechano-hypoxia conditioning and collaborates with aerospace initiatives through Canadian Space Agency partnerships. Current work explores simulated microgravity effects on human meniscus models and develops clinically applicable matrices incorporating bioactive molecules for cartilage formation.

• Tissue Engineering
• Regenerative Medicine
• Stem Cell Biology
• +5 more

Kiven Erique Lukong is a Professor in the Department of Biochemistry, Microbiology & Immunology at the University of Saskatchewan's College of Medicine. His research focuses on breast tumor kinase (BRK) and related kinases, particularly their roles in breast cancer progression and metastasis. He holds a Ph.D. in Biochemistry from the University of Montreal and has collaborated with institutions globally, including the University of Ngaoundere in Cameroon. His work is supported by grants from NSERC and the University of Saskatchewan. Education: B.Sc. Biochemistry, Keele University, UK (1988) B.A. French, Keele University, UK (1988) M.A. Linguistics, University of Montreal (1992) M.Sc. Biochemistry, University of Montreal (1996) Ph.D. Biochemistry, University of Montreal (2002) Research Interests: Dr. Lukong's lab investigates BRK and related kinases (FRK, SRMS) in breast cancer. Key areas include: BRK's role in tumor formation and metastasis BRK as a diagnostic/prognostic marker Interactions with estrogen receptor signaling Phosphoproteomics and kinase substrate identification His work combines molecular biology, proteomics, and translational research to uncover therapeutic targets. Grants & Collaborations: NSERC Operating Grant (2017–2021) CoMBRIDGE Funding Grant (2019–2022) Memorandum of Understanding with University of Ngaoundere (2018) Labs & Teams: The Lukong Lab at the University of Saskatchewan is equipped for advanced proteomics, cell biology, and in vivo modeling. Collaborations include Dr. Anne-Claude Gingras' lab for Bio-ID/Mass Spectrometry training.

• Breast Cancer Research
• Molecular Oncology
• Cellular Signaling Pathways
• +3 more

Dr. Scott Napper is a Professor in the Department of Biochemistry, Microbiology & Immunology at the University of Saskatchewan, with a concurrent appointment as Senior Scientist at VIDO-Intervac. His work bridges structural biochemistry and immunology to address challenges in protein misfolding diseases, vaccine development, and host-pathogen signaling. Ph.D., Department of Biochemistry, 1999, University of Saskatchewan B.Sc. Honours, Department of Biochemistry, 1994, University of Saskatchewan Dr. Napper's research focuses on: Vaccine development for prion diseases and proteinopathies Kinome analysis for infectious disease mechanisms Peptide array technology for high-throughput signaling studies Science education outreach to secondary and undergraduate students Recent publications highlight his work in: Prion disease immunization strategies Host kinome responses to prebiotics Epitope immunogenicity prediction Comparative stress response analysis in livestock Scientific recognition includes: Three-time recipient of University of Saskatchewan Teaching Excellence Award His research program integrates computational approaches with experimental validation to identify therapeutic targets in: Infectious diseases of humans and animals Cancer signaling pathways Protein misfolding disorders Food contaminant toxicity

• Vaccine Development
• Prion Diseases
• Kinome Analysis
• +3 more

Dr. Siavash Vahidi is an Assistant Professor in the Department of Molecular and Cellular Biology at the University of Guelph. His research focuses on understanding the structure, function, and dynamics of large biomolecular machines, particularly those involved in protein degradation in pathogens like Mycobacterium tuberculosis . He employs advanced techniques such as mass spectrometry (H/D exchange, native MS) and high-field NMR spectroscopy to study these systems. His lab is actively recruiting students and postdocs, emphasizing a commitment to diversity and training in cutting-edge methodologies. Education: BSc in Chemistry, National University of Iran, Tehran PhD in Chemistry and Biochemistry, University of Western Ontario CIHR Postdoctoral Fellowship, University of Toronto & The Hospital for Sick Children Research: Key interests include the M. tuberculosis proteasome system, ClpP proteases in human mitochondria, and the role of allostery in substrate selection. The lab’s integrative approach combines structural biology with biochemical and computational methods, aiming to identify novel drug targets for tuberculosis and other diseases. Awards: Paul de Mayo Award for Best PhD Thesis Lab & Training: The Vahidi Lab emphasizes interdisciplinary training, offering expertise in mass spectrometry, NMR, and computational tools (e.g., Python, Linux). Supported by grants and collaborations, the lab fosters an inclusive environment with a strong focus on mentorship. Lab Resources: Website: Vahidi Lab Twitter: @VahidiLab

• Structural Biology
• Protein Degradation
• Mycobacterium tuberculosis Research
• +4 more

Dr. Patrick O'Donoghue is an Associate Professor and Canada Research Chair in Chemical Biology at Western University's Department of Biochemistry, Faculty of Science. His research focuses on proteome diversity mechanisms through protein modifications and mistranslation, with implications for cancer and neurodegenerative diseases. Education: Ph.D. from University of Illinois, Postdoctoral training at Yale University Research highlights include pioneering genetic code expansion techniques for programmed protein modifications in human cells and developing fluorescent reporters to visualize translation errors. His work connects protein synthesis fidelity to disease pathways through tRNA mutant studies. Scientific Contributions: 2024 Mechanisms and Delivery of tRNA Therapeutics review in Chemical Reviews 2023 HARS Disease Therapeutics in Genes (Basel) 2022 Expanding Codon Size in eLife 2021 Fluorescent Mistranslation Reporters in Cells Contact: Office in Medical Sciences Building Room 388, Phone: 519.850.2373, Email: patrick.odonoghue@uwo.ca

• Proteome Diversity
• Post-Translational Modifications
• Genetic Code Expansion
• +5 more

Dr. Shideh Kabiri Ameri serves as Associate Professor in the Department of Electrical and Computer Engineering at Queen's University, where she joined in September 2018 after completing postdoctoral research at the University of Texas at Austin. Her interdisciplinary expertise bridges nanomaterials engineering and biomedical applications, with particular focus on developing imperceptible wearable sensors for continuous health monitoring. Her educational foundation includes: PhD in Electrical Engineering (2015) from Tufts University Master's and Bachelor's degrees in Physics (solid state) AS degree in Medical Laboratory Sciences Dr. Ameri's research program centers on 2D material-based electronic devices for wearable bioelectronics, human-machine interfaces (HMI), and mobile healthcare systems . Her lab pioneered graphene electronic tattoos (GETs) that achieve unprecedented skin conformity while recording high-fidelity physiological signals. Current work emphasizes ultrasoft hydrogel-based sensors that eliminate motion artifacts and enable months-long wear without skin irritation, representing a paradigm shift from conventional rigid medical devices toward truly imperceptible health monitors. Analysis of her 40+ publications reveals a strategic evolution from fundamental nanomaterial characterization toward clinically viable systems. Recent work (2021-2025) demonstrates increasing sophistication in multimodal sensing (simultaneous ECG/EEG/temperature), reusable sensor architectures , and wireless power integration . The trajectory shows clear progression from lab prototypes to FDA-pipeline devices, particularly in cardiac and neurological monitoring applications. Her scientific recognition includes: Rising Star in EECE 2017 award Dr. Ameri leads the Ameri Nano Research Group which operates advanced nanofabrication facilities for developing next-generation bioelectronic interfaces. Her research has attracted significant media attention from BBC, IEEE Spectrum, and Phys.Org, highlighting real-world impact in remote patient monitoring. The group actively collaborates with medical institutions to translate innovations into point-of-care diagnostics, with current projects focusing on in-ear physiological monitors and strain-neutralized neural recording systems. The research team maintains strong industry partnerships for commercializing soft bioelectronics, with particular emphasis on creating accessible health monitoring solutions for underserved communities through low-cost manufacturing approaches.

• 2D material based electronic devices
• Wearables
• Bioelectronics
• +3 more

James R. Green is a Professor in the Department of Systems and Computer Engineering at Carleton University , where he has been a faculty member since 2005. He holds a PhD from Queen's University and is a licensed Professional Engineer (P.Eng.) and Senior Member of IEEE. His work integrates machine learning, biomedical informatics, and high-performance computing. His educational background includes: B.A.Sc. in Systems Design Engineering, University of Waterloo (1998) M.Sc.(Eng.), Queen's University (2000) PhD, Queen's University (2005) Dr. Green's research focuses on machine learning challenges in biomedical informatics , particularly class imbalance and rare event prediction. Key areas include protein structure, function, and interaction prediction; microRNA detection in unique species; non-contact neonatal monitoring; and accelerating scientific computing via parallel architectures like the Cell BE processor. His lab has developed several widely used bioinformatics tools such as PIPE, ProtDCal, and PCI-SUMO. His recent publications reflect a strong trend in computational biology and machine learning , with applications in proteomics, genomics, and medical diagnostics. He has published over 100 peer-reviewed papers and secured funding from NSERC, CIHR, CFI, ORF, OCE, MITACS, and IBM. Scientific and teaching recognitions include: Three teaching awards NSERC Best Project Award (twice: 2006-2007 and 2007-2008) Multiple student projects resulting in conference papers (e.g., CMBEC) He has supervised numerous undergraduate capstone projects in areas such as assistive technologies, robotic systems, and bioinformatics. His teaching portfolio includes courses in Pattern Classification, Machine Learning, Computer Architecture, and Biomedical Engineering. He leads an active research group that bridges computer engineering and life sciences, fostering interdisciplinary collaboration. Lab and research team initiatives include: Development of open-access web servers for protein analysis Collaborations with biologists and clinicians Integration of hardware and software for medical applications

• Machine Learning
• Biomedical Informatics
• Computational Biology
• +9 more

Dr. Keith Wheaton is an Assistant Professor in the Department of Biochemistry, Microbiology and Immunology at the University of Ottawa , and serves as the Director of the Translational Molecular Medicine (TMM) Undergraduate Program . He is actively involved in curriculum development and science education, with a focus on active learning and student engagement in molecular medicine and aging biology. Education: BSc, Biochemistry – University of Guelph BEd, Adult Education – Brock University PhD, Biochemistry & Molecular Biology – University of Calgary Post-doctoral Research – University of Toronto & York University Research Interests: Dr. Wheaton’s research spans molecular biology , cellular senescence , and cancer biology , with a particular emphasis on the p53 tumor suppressor pathway and its role in aging and Hutchinson-Gilford Progeria Syndrome . His work has contributed to understanding how replication stress and genomic instability drive premature aging phenotypes. He is also a leader in science education , developing inquiry-based laboratory courses and integrating active learning strategies into biology and biochemistry curricula. He has taught in the Ottawa-Shanghai Joint School of Medicine and participates in the SEA PHAGES program, which engages undergraduates in genomics research. Scientific Contributions: Dr. Wheaton has published extensively in high-impact journals such as Molecular and Cellular Biology , Journal of Biological Chemistry , and Aging Cell . His work explores the molecular underpinnings of aging, the role of p53 in cellular senescence, and epigenetic regulation via ubiquitination and chromatin modification. Teaching & Outreach: He leads the TMM undergraduate program and teaches courses on aging, cancer biology, and molecular biology. He encourages undergraduate research and welcomes students to contact him for opportunities in the TMM program.

• Molecular Biology
• Cellular Senescence
• Cancer Biology
• +5 more