Jonas Fischer is the head of the Explainable Machine Learning group at the Max Planck Institute for Informatics, Department of Computer Vision and Machine Learning. His research focuses on interpreting complex machine learning models, particularly in genomics and healthcare, aiming to enhance robustness and alignment with human decision-making. Prior to his role at MPI, he was a postdoctoral fellow at Harvard University's Department of Biostatistics, where he worked on interpretable models for gene regulatory systems in cancer. Education: PhD in Computer Science from Saarland University (2022), with a thesis titled More than the sum of its parts , exploring the intersection of pattern mining and deep learning. He has contributed to advancing methods in neural network pruning, federated learning, and low-dimensional embeddings (e.g., dtSNE, Mercat). His work bridges computational biology, data mining, and machine learning, with applications in DNA methylation analysis, graph-based differential networks, and biomedical informatics. Key research areas include: (1) Explainable AI and neural network interpretability, (2) Biomedical applications of machine learning (e.g., gene regulatory networks, cancer genomics), (3) Low-dimensional embeddings and visualization techniques, (4) Federated learning for privacy-preserving collaborative models, and (5) Pattern mining for error analysis in NLP and classification tasks. Publications span top venues like NeurIPS, ICLR, Bioinformatics, and Genome Biology. His group develops tools such as BONOBO for omics data integration and node2vec2rank for scalable graph analysis. He actively collaborates with biomedical researchers to address challenges in data-driven healthcare and precision medicine.
Max Planck Institute for Molecular GeneticsGermany
Professor Knut Reinert is a leading figure in algorithmic bioinformatics at the Free University of Berlin, where he holds a professorship in the Department of Mathematics and Computer Science. He also maintains a significant affiliation with the Max Planck Institute for Molecular Genetics in Berlin, where he leads the Efficient Algorithms for Omics Data group. His research spans both institutions through the Reinert Lab, which focuses on developing novel computational approaches for biological data analysis. Reinert's educational background includes a Diploma in Computer Science (1994) and a Doctorate (Dr. Ing./Ph.D., 1999, with honors) from the Max-Planck-Institut for Computer Science and Universität des Saarlandes in Saarbrücken. Prior to his professorship, he worked as a computer scientist under Prof. Gene Myers at Celera Genomics in Rockville, USA (1999-2002). His primary research interests center on algorithmic bioinformatics with specific focus on developing novel algorithms and data structures for biomedical mass data analysis. This includes creating mathematical models for genomic sequence analysis and algorithms for mass spectrometry data to detect differential protein expression between normal and diseased samples. His work bridges the gap between computational tool development and practical biological applications, with particular emphasis on NGS and proteomics data. The publications and projects led by Prof. Reinert demonstrate a consistent focus on advancing computational methods in bioinformatics. His research spans genomic sequence analysis, RNA research (particularly long non-coding RNAs), parallel computing applications, and GPU acceleration for biological data processing. The work shows increasing sophistication in handling large-scale biological datasets through innovative algorithmic approaches. Intel® Parallel Computing Center designation for his lab CUDA Research Center status DFG funding of 530 thousand Euros for RNA research de.NBI funding of 2 million Euros BMBF funded projects 'LIVE-DREAM' and 'EssBar' Prof. Reinert leads multiple significant research projects and has established strong collaborations with international partners including Texas A&M, Kings College London, Eberhardt-Karls Universität Tübingen, Robert-Koch-Institute, and various Turkish institutions. His lab receives funding from major organizations including DFG, BMBF, and Intel. The Reinert Lab maintains active teaching responsibilities at FU Berlin, offering courses at BSc, MSc, and PhD levels using both traditional and innovative learning concepts like e-learning and inverted classrooms. The Reinert Lab consists of two interconnected research groups that work closely with experimental biologists and medical researchers to develop practical computational solutions for real-world biological problems. The lab has established itself as a key player in the German and international bioinformatics community through its development of the widely-used SeqAn library and participation in national infrastructure initiatives.
Professor Matthias Mann is a world-leading scientist serving as Director of the Proteomics and Signal Transduction department at the Max Planck Institute of Biochemistry in Martinsried, Germany, and Director of the Proteomics department at the Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Denmark. With an h-index exceeding 277 and over 350,000 citations, he is recognized as the highest cited German researcher and one of the most influential scientists globally in proteomics. His educational background includes: Ph.D. in Chemical Engineering from Yale University (1988) Master's Degree in Physics from Georg August University Göttingen (1984) Bachelor's of Arts in Mathematics from Georg August University Göttingen (1982) Professor Mann's research focuses on advancing mass spectrometry-based proteomics to understand biological systems at the protein level. His work spans technological developments in mass spectrometry, bioinformatics and computational analysis, signal transduction and posttranslational modifications, and clinical proteomics applications for disease diagnosis and treatment. The Mann lab has pioneered groundbreaking methods like SILAC for quantitative proteomics and MaxQuant for proteome data analysis. Their vision is to translate proteomics knowledge into clinical practice for predictive, diagnostic, and preventive medicine, with recent work focusing on AI-guided platforms for analyzing proteomes from minimal tissue samples. Analysis of Professor Mann's recent publications reveals a strong trend toward clinical applications of proteomics, particularly in cancer research, metabolic diseases, and neurodegenerative disorders. His work increasingly integrates spatial proteomics, single-cell resolution techniques, and artificial intelligence approaches to uncover disease mechanisms and identify potential biomarkers, with a clear shift from basic technology development toward direct clinical applications and personalized medicine. Professor Mann has received numerous prestigious awards throughout his career: 2025: Elected member of the American National Academy of Sciences 2024: Dr. H.P. Heineken Award for Biochemistry and Biophysics 2023: Otto Warburg Medal 2019: Nominated member of the Bavarian Academy of Sciences 2013: Elected member of Leopoldina German National Academy of Sciences 2012: Körber European Science Award, Louis-Jeantet Foundation Prize for Medicine, Ernst Schering Prize, and Leibniz Prize Professor Mann leads a highly collaborative research team involved in multiple international networks including the Bill & Melinda Gates Foundation, Michael J. Fox Foundation for Parkinson's Research, CLINSPECT-M, and Munich Heart Alliance. His lab has mentored numerous successful researchers, with several former postdocs receiving prestigious ERC Starting Grants. The Mann group has developed innovative clinical proteomics pipelines for analyzing archived tissue specimens and body fluids, aiming to identify protein markers for early detection of diseases such as diabetes and cancer. The Mann lab operates across two major research centers with state-of-the-art mass spectrometry facilities. Their Clinical Knowledge Graph platform integrates multi-omics data with extensive metadata, creating an ecosystem for machine learning applications in proteomics. Current research focuses on developing highly sensitive methods that can profile thousands of proteins from minimal cell samples, enabling the identification of critical disease-related proteins and supporting the development of individualized therapies.
Max Planck Institute of Colloids and InterfacesGermany
Dr. Yolanda Gil is a Research Professor in Computer Science and Spatial Sciences at the University of Southern California, where she serves as Principal Scientist and Senior Director for Strategic Initiatives in Artificial Intelligence and Data Science at the Information Sciences Institute (ISI). She is also the Director of AI and Data Science Initiatives in the Viterbi School of Engineering and leads the USC Center for Knowledge-Guided Interdisciplinary Data Science (CKIDS). Dr. Gil received her Licenciatura in Computer Science from the Polytechnic University of Madrid and her M.S. and Ph.D. in Computer Science from Carnegie Mellon University, with a focus on artificial intelligence and cognitive science. Her research focuses on developing AI approaches that use knowledge to accelerate scientific discovery processes. Her key research interests include knowledge capture and representation, semantic workflows, ontology tools, scientific discovery methods, task-based collaboration, provenance tracking, knowledge networks, reproducibility in science, and machine learning for data analysis. She collaborates with scientists across multiple domains to improve how scientific knowledge is created, shared, and used. Dr. Gil's work has significant impact across multiple scientific domains including climate science, neuroscience, and omics research. Her projects demonstrate her commitment to building knowledge-guided systems that transform how scientists conduct research. She has pioneered approaches to capture the provenance of scientific experiments and to automate the analysis of complex scientific data. Fellow of the Association for Computing Machinery (ACM) Fellow of the Association for the Advancement of Science (AAAS) Fellow of the Institute of Electrical and Electronics Engineers (IEEE) Fellow of the Association for the Advancement of Artificial Intelligence (AAAI) 24th President of the Association for the Advancement of Artificial Intelligence Co-chair of the CRA/AAAI 20-Year Artificial Intelligence Research Roadmap for the US Initiator and leader of the W3C Provenance Group that resulted in a widely-used standard for web trust As an educator and leader, Dr. Gil directs the Data Science Program in Computer Science and serves as Co-Director of multiple joint MSc programs including Communication Data Science, Spatial Data Science, Environmental Data Science, Public Policy Data Science, and Healthcare Data Science. She also leads the new dual degree USC-Tsinghua University on Communication Data Science. Her leadership extends to mentoring numerous students and researchers in AI and data science. Through the USC Center for Knowledge-Guided Interdisciplinary Data Science (CKIDS), Dr. Gil organizes DataFest events each semester, fostering collaboration and innovation in data science across disciplines.
Leibniz Institute for Zoo and Wildlife ResearchGermany
Omer Bayraktar is a Group Leader at the Wellcome Sanger Institute , leading research in the Cellular Genomics Programme. His work focuses on decoding human brain cellular diversity using spatial transcriptomics , imaging , and functional screening to study neural complexity in health and disease. Bayraktar's educational background includes a PhD from HHMI under Chris Doe, investigating neural diversity development in Drosophila , followed by postdoctoral work at University of California, San Francisco and University of Cambridge as a Life Sciences Research Foundation Fellow. He developed a spatial transcriptomic pipeline during his postdoc to analyze astrocyte heterogeneity in the cerebral cortex. His research explores neural cell type mapping , glial-neuronal interactions , and cellular pathways in neurodevelopmental disorders . Recent publications emphasize 3D tissue mapping , multi-omic integration , and computational tools like Cell2fate and WebAtlas. His work bridges neurogenetics and computational biology to advance understanding of human tissue ecosystems. Bayraktar's lab collaborates with the Human Cell Atlas initiative and develops technologies such as automated histology pipelines and highly-multiplexed smFISH for molecular cell typing. His team also investigates glia-based therapies and astrocyte functional heterogeneity in neurodevelopmental contexts. Key scientific contributions include: Discovering astrocyte layer patterns independent of neuronal laminae Developing cell2location for spatial cell mapping Characterizing Drosophila neural stem cell models with human relevance Notable awards include the Life Sciences Research Foundation Fellowship during his postdoctoral training. His current group includes a PhD student , Senior Data Scientists , and Bioinformaticians .
Bertram Müller-Myhsok is a Research Professor and Research Group Leader at the Max Planck Institute of Psychiatry in Munich, Germany. His research focuses on statistical genetics and transcriptomic data analysis in psychiatric disorders, particularly major depression, PTSD, schizophrenia, and their treatment responses. He integrates machine learning with genetic and clinical data to develop predictive models and stratified treatment approaches. Professional activities include leadership roles in the International Max Planck Research School for Translational Psychiatry and collaborations with institutions like the Institut du Cerveau (Paris) and Bernhard Nocht Institute (Hamburg). His work spans genetic epidemiology, psychiatric genomics, and precision medicine, with over 400 publications in high-impact journals. Key research areas include identifying genetic risk factors for mental disorders, developing polygenic scores, and leveraging omics data to uncover disease mechanisms. He leads projects like Psych-STRATA, a Horizon Europe-funded initiative advancing personalized psychiatry through pharmacogenomics.
University Medical Center Hamburg-EppendorfGermany
Prof. Dr. med. Franz Lennard Ricklefs is a Senior Physician and Head of the Working Group at the Department of Neurosurgery, University of Hamburg Faculty of Medicine. He is a Medical Specialist in Neurosurgery with cross-disciplinary expertise in neuro-oncology, molecular pathology, and extracellular vesicle research. Affiliations: University Medical Center Hamburg-Eppendorf (UKE), European Liquid Biopsy Society (ELBS), International Consortium on Meningiomas (ICOM) Research Interests: His work focuses on neurosurgical oncology, particularly glioblastoma and meningioma pathobiology. He investigates DNA methylation patterns, extracellular vesicle biomarkers, and liquid biopsy implementation in clinical neuro-oncology. Additional interests include surgical outcomes for epilepsy and aneurysm management. Article Trends: Over the last decade, Dr. Ricklefs has published extensively on: Extracellular vesicle applications as liquid biopsy markers DNA methylation subclasses for glioblastoma and meningioma Multicenter surgical outcome benchmarking Immune evasion mechanisms in neuro-oncology Technological innovations in neurosurgical visualization Molecular characterization of rare CNS tumors Professional Contributions: He co-authored the MISEV2023 guidelines for extracellular vesicle studies and participates in international consensus reviews for meningioma classification. His collaborations span institutions across Europe and North America.
Nikolaus Rajewsky is a leading Professor at the Max Delbrück Center for Molecular Medicine (MDC) and Charité – Universitätsmedizin Berlin , where he founded and directs the Berlin Institute for Medical Systems Biology (BIMSB) . His lab integrates experimental (biochemistry, molecular biology) and computational (bioinformatics, physics) approaches to study RNA regulation in gene expression , with applications to developmental biology, regeneration, neurodegenerative diseases, and cancer . Using model systems like C. elegans , planaria, and human brain organoids, his team pioneers cutting-edge methods such as MirDeep , DistMap , and FLAM-seq for RNA analysis. His research focuses on single-cell transcriptomics , spatial RNA sequencing , and circular RNA (circRNA) regulation , revealing novel roles for circRNAs like CDR1as in neuropsychiatric disorders. Recent work includes 3D tumor microenvironment mapping and computational modeling of RNA metabolism in diseases. Scientific Awards : Gottfried Wilhelm Leibniz Prize (2012) EMBO Membership (2010) Honorary PhD, Sapienza University of Rome (2014) Berlin Science Award (2009) His team's recent articles highlight breakthroughs in 3D spatial transcriptomics , circRNA degradation mechanisms , and mitochondrial disease modeling using human brain organoids. The lab actively collaborates with clinical partners across Charité and European institutions, driving the LifeTime initiative for cell-based interceptive medicine.
Weierstrass Institute for Applied Analysis and StochasticsGermany
Marco Cuturi is a Research Scientist at Apple ML Research in Paris and Professor of Statistics at CREST-ENSAE, Institut Polytechnique de Paris. His work bridges machine learning , optimal transport , and optimization , with applications in time-series analysis , kernels , and multiresolution methods . He has held academic roles at Kyoto University and Princeton University, and previously worked in the financial industry. Research Interests: Optimal transport theory and computational methods Kernel design for structured data and histograms Time-series alignment and soft-DTW Entropic regularization in optimization Applications to computer vision and genomics Teaching: Cuturi has taught courses on linear optimization at Princeton, geometric methods in machine learning at Kyoto, and scientific English. He has also organized machine learning summer schools in Kyoto, Les Houches, and other international venues. Recent Trends: His 2024-2025 publications focus on entropic optimal transport solvers, disentangled representation learning via Gromov-Monge gaps, and applications to text-to-image diffusion models. Collaborative work with institutions like Google Research, MIT, and University of Tokyo highlights his interdisciplinary impact.
Ralf Zimmer is a Full Professor for Practical Informatics and Bioinformatics at Ludwig Maximilian University of Munich (LMU) since 2001, affiliated with the Department of Informatics in the Faculty of Mathematica, Informatics and Statistics. He concurrently serves as Head of Section III and Head of the Research Group Network Regulation and Modeling / Machine Learning at the Leibniz Institute for Food Systems Biology at TUM (Leibniz-LSB@TUM) in Freising, Germany. His academic foundation includes a Diploma with distinction in Computer Science, Applied Mathematics and Operations Research from the University of Bonn (1981-1986), followed by a summa cum laude Doctorate in Computer Science and Applied Mathematics from CAU Kiel in 1990, where he received dual honors: the CAU Dissertation Award and Best Dissertation Award. Zimmer's research pioneers the integration of bioinformatics, systems biology, and machine learning to decode molecular food-consumer interactions. His group develops causal system models for biological networks, validated through in silico simulations and multi-omics perturbation experiments (transcriptomics/proteomics). Core methodologies include network regulation modeling, algorithmic bioinformatics, and database construction linking food compounds to biochemical networks and cellular phenotypes, with translational goals for food and biotech innovation. His 14 most recent publications (2012-2024) reveal dominant trends in multi-omics immunology and cardiovascular research, featuring computational innovations for high-throughput data analysis. Key themes include host-pathogen dynamics (viral infections), inflammatory disease mechanisms (atherosclerosis), and methodological advances in proteomics/transcriptomics, consistently bridging fundamental bioinformatics with clinical applications. Major scientific recognitions include: CAU Dissertation Award and Best Dissertation Award (1990) Director of LMU's Informatics Department (2010-2012) DFG Review Board membership for biomedical foundations (2008-2016) Leadership of the DFG Bioinformatics Munich Center (2001-2008) Academic Senate election at LMU München (2011) Zimmer directs LMU/TUM's joint B.Sc./M.Sc. bioinformatics programs since 2001 as founding architect of the DFG-funded Bioinformatics Munich initiative. His educational leadership spans spokesperson roles for international training groups (IRTG RECESS), collaborative research centers (SFB1123 Atherosclerosis), and elite programs (Data Science, Munich Center for Machine Learning). Grant stewardship includes directing the DFG Bioinformatics Munich Center and shaping national funding policy via the DFG review board. At Leibniz-LSB@TUM, his research group pioneers databases connecting food compounds to cellular phenotypes through molecular networks, collaborating with Munich universities, clinics, and biotech partners to develop high-throughput sequencing/proteomics applications for future food and health innovations.
Helmholtz Centre for Environmental ResearchGermany
Prof. Dr. Jörg Hackermüller is a computational biologist with expertise in Omics data integration Toxicology Environmental risk assessment Non-coding RNA biology . He serves as Head of the Department of Computational Biology and Chemistry at the Helmholtz Centre for Environmental Research (UFZ) since 2024 and holds a Professorship at the Faculty of Mathematics and Computer Science at Leipzig University since 2021. His research focuses on Developing AI methods for chemical toxicity prediction Multi-omics integration for mechanistic toxicology Data standardization in environmental monitoring Non-coding RNAs as biomarkers in disease and toxicity and has produced 15+ recent publications spanning tools like multiGSEA and deepFPlearn+ . He collaborates with teams across UFZ Leipzig University Novartis Fraunhofer Institute and leads projects like InCeTo and SafePol , integrating exposome research with systems biology.
Andreas Maier is a Researcher at the University of Hamburg's Faculty of Mathematics, Informatics and Natural Sciences, affiliated with the Computational Systems Biology department. He began his PhD in May 2021 with Cosy.Bio (Center for Systems Biology) at UHH, focusing on drug repurposing projects such as REPO-TRIAL. Previously, he completed a Bioinformatics master's thesis at TUM (Technical University of Munich), developing a web application for analyzing molecular disease networks. His research interests emphasize network medicine, drug repurposing, and computational tools for biomedical discovery. He has contributed to platforms like NeDRex-Web, Drugst.One, and BioCypher, which democratize access to systems medicine workflows. His work bridges heterogeneous data integration, federated learning for rare diseases, and quantum computing applications in genetics. Maier's publications highlight innovations in knowledge graph-based drug discovery, privacy-preserving federated learning, and single-cell network analysis. He actively develops open-source bioinformatics tools to address challenges in disease module identification and patient stratification. His projects align with the REPO4EU consortium and other collaborative initiatives in translational bioinformatics.
Paul J. Kennedy is a Professor at the University of Technology Sydney's Centre for Artificial Intelligence. He holds a PhD from the same institution (1999). His research focuses on machine learning applications in healthcare, bioinformatics, medical imaging, and data mining. Key areas include developing algorithms for genomic data analysis, healthcare pathway modeling, and edge-cloud frameworks for omics data. Education: PhD in Artificial Intelligence (1999, UTS). Research interests span machine learning, health informatics, and data compression. Notable work includes studies on administrative health records, lung nodule detection, and virtual reality-based cancer cohort analysis. He has co-authored over 100 publications across journals like BMC Bioinformatics, IEEE Transactions, and Artificial Intelligence in Medicine. Advising: Collaborates extensively with students/researchers but no explicit student list provided. Grants and labs: Active in interdisciplinary projects involving medical and computational teams, though specific grants are not detailed here.
Prof. Dr. Andreas Beyer holds a faculty position at the University of Cologne, affiliated with the Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases (CECAD) and the Cologne Excellence Cluster for Cellular Mechanisms in Cancer (CMMC). His research focuses on systems-level analysis of aging processes in humans and model organisms, integrating genomic, proteomic, and computational approaches. Key interests include understanding how genetic variation influences protein networks, developing algorithms for big data analysis, and exploring epigenetic mechanisms related to longevity. Research projects include studying age-associated changes in transcriptional elongation, molecular networks in kidney disease, and the impact of dietary restriction on aging. His group develops tools for proteomics and systems biology, such as methods for analyzing limited proteolysis data and single-cell resolution imaging. Collaborative efforts emphasize translational research in aging-related diseases and drug discovery. Prof. Beyer’s work spans computational biology, molecular genetics, and translational medicine. Notable contributions include identifying epigenetic changes linked to longevity and developing predictive models for age-related disease progression. His lab’s projects often involve multi-omics integration and network-based analyses to uncover disease mechanisms. His research has implications for personalized medicine, cancer biology, and interventions to extend healthspan. Current efforts include optimizing drug combinations targeting aging processes and advancing proteomic technologies for clinical applications.
Helmholtz Centre for Environmental ResearchGermany
Prof. Dr. Beate Escher is Head of the Department of Cell Toxicology at the Helmholtz Centre for Environmental Research (UFZ) in Leipzig, Germany. She holds professorial positions at Eberhard Karls University of Tübingen , is a Privatdozent at ETH Zurich , and is affiliated with the University of Queensland and Griffith University in Australia. Her research program focuses on advancing in vitro bioassays and New Approach Methods (NAMs) for environmental and human health risk assessment of micropollutants. Her research interests lie at the intersection of environmental toxicology , molecular toxicology , and exposure science . She develops and applies bioanalytical tools for water quality assessment, with a focus on pharmaceuticals, pesticides, and transformation products. Her work includes mechanism-based toxicity assessment , toxicokinetic-toxicodynamic (TKTD) modeling , and the development of the CITEPro robotic bioassay platform for high-throughput screening. She integrates omics data , computational modeling , and machine learning to improve chemical hazard characterization. Recent publications highlight trends in chemical mixture toxicity , safe-by-design chemicals , ionic compound assessment , and machine learning applications in toxicology. Her work increasingly leverages data-driven approaches to prioritize contaminants and predict biological effects across species. Scientific Awards: Highly Cited Researcher (Web of Science/Clarivate, Top 0.1%, 2020) Outstanding Achievements in Environmental Science and Technology (ES&T & ACS ENVR, 2023) Advising and Grants: She supervises multiple doctoral students and leads major collaborative projects such as InCeTo, MibiTox, nanoINHALE, and SafePol. She received an Australian Research Council grant (2011–2014) and leads Swiss National Science Foundation-funded initiatives. She was a member of the German Science Council (2017–2024) and serves on the Board of Reviewing Editors of SCIENCE . Labs and Teams: She leads the Cell Toxicology team at UFZ, which includes researchers such as Dr. Luise Henneberger, Dr. Julia Huchthausen, and Dr. Haotian Wang. The team operates the CITEPro platform and contributes to international consortia focused on exposome research and chemical safety.
