Find Academic Supervisors

G J HughesView profile

Tutor

• Epigenetics
• Molecular Biology
• Genomics
• +3 more

G J Hughes is a Tutor in Philosophy at Campion Hall, University of Oxford. His research focuses on epigenetic mechanisms, genomic regulation, and their implications in diseases such as leukemia and genetic disorders. He is particularly known for contributions to understanding chromatin architecture, enhancer function, and single-cell genomics technologies. Education: Not explicitly stated in provided texts. Research interests include the interplay between chromatin structure and gene expression, with a focus on transcriptional regulation in hematopoiesis and cancer. Key areas of exploration involve super-enhancers, cohesin dynamics, and computational models for predicting regulatory elements. His work bridges basic biological mechanisms and clinical applications, such as improving diagnostic yield through whole-genome sequencing. Publications highlight advancements in technologies like Capture-C, scATAC-seq, and deep learning-based tools (e.g., REnformer) for analyzing 3D genome interactions. These methods enable high-resolution mapping of regulatory landscapes and have implications for understanding developmental disorders and oncogenesis. Awards: No specific honors or fellowships are mentioned. Advising & Grants: Advising relationships are not listed; grants and funding details are absent from the provided texts. However, his collaborative projects suggest involvement in large-scale genomic initiatives and computational biology frameworks. Labs/Teams: Affiliated with interdisciplinary teams focusing on genomics, epigenetics, and computational biology, likely through Oxford’s broader academic networks despite his primary appointment in Philosophy.

Ronald L.A.W. BleysView profile

Professor

• Clinical Anatomy
• Vascular System
• Autonomic Nervous System
• +4 more

Ronald L.A.W. Bleys is a Full Professor of Clinical Anatomy at Utrecht University, affiliated with the University Medical Center Utrecht. He has served as head of the Department of Anatomy since 2000 and has been a faculty member since 1987. His educational background includes an MD (1986) and a PhD (1995) from Utrecht University, with research conducted at the Royal Free Hospital School of Medicine in London. Bleys is registered as a medical morphological investigator by the Foundation for Biomedical Scientific Research Training (SMBWO). Ronald Bleys' research focuses on the interplay between the vascular system and autonomic nervous system, particularly the autonomic regulation of inflammatory responses. His work spans clinical anatomy, neurovascular interactions, and developmental biology, with recent publications on eyelid/orbital embryology and facial muscle spatial analysis. Honorary doctorate from Tbilisi State Medical University (2015) Outstanding Teacher Award from Utrecht University (2013) Medal of honor from Medical University Varna (1997) Talma Eykman award for Teacher of the year (1990) Bleys co-authors clinical anatomy studies and collaborates on surgical innovations, including 3D MRI analysis of facial muscles and orbital metastatic pathways. He serves on scientific advisory committees and editorial boards.

• Cancer Genomics
• Epigenetics
• Bioinformatics
• +2 more

Timothy J Triche is Professor of Pathology at the Keck School of Medicine, University of Southern California. He directs research in cancer genomics, epigenetics, and bioinformatics, with emphasis on pediatric malignancies. His laboratory develops computational tools for genomic analysis and focuses on translating molecular discoveries into clinical diagnostics. Research spans pediatric acute myeloid leukemia, prostate cancer, and sarcoma biology, integrating multi-omics approaches. Key interests include liquid biopsy development, epigenetic dysregulation, and gene fusion mechanisms in oncogenesis. Publications demonstrate consistent focus on molecular diagnostics and bioinformatic innovation, with recent work advancing single-cell analysis methodologies and non-invasive cancer profiling. Earlier foundational studies established mechanisms of fusion oncoproteins in sarcomas.

Marianne BronnerView profile

Professor

• Cellular and Developmental Biology
• Evolutionary Biology
• Neuroscience
• +5 more

Marianne Bronner is the Edward B. Lewis Professor of Biology and Director of the Beckman Institute at the California Institute of Technology. She holds a Sc.B. from Brown University (1975) and a Ph.D. from Johns Hopkins University (1979). Her career at Caltech spans roles including Ruddock Professor (2000-21), Distinguished Professor (2021), and Executive Officer (2013-16). Her research focuses on neural crest development, integrating molecular, cellular, and evolutionary approaches. Key areas include neural crest induction, placode formation, and their roles in craniofacial and sensory organ development. She explores evolutionary innovations like the vertebrate head by comparing lamprey, amphioxus, and jawed vertebrates. Her lab investigates mechanisms of cell migration, epigenetic regulation, and oncogenic processes linked to neural crest-derived cancers. Techniques employed include transcriptomics, CRISPR/Cas9, laser speckle imaging, and lineage tracing in chick, zebrafish, and lamprey models. Recent work highlights neural crest contributions to heart regeneration and neurofibromatosis modeling in zebrafish. The lab collaborates with the Caltech Women in STEM initiative and has pioneered tools for in vivo imaging and genetic manipulation. Lab Leadership: Bronner Lab at Caltech Key Projects: Neural crest gene regulatory networks, placode evolution, cancer biology Tools: Laser speckle imaging, CRISPR, lineage tracing Her work bridges developmental, evolutionary, and translational research, with implications for birth defects, cancer, and regenerative medicine.

Takako MakitaView profile

Assistant Professor

• Neurobiology
• Developmental Biology
• Molecular Biology
• +3 more

Takako Makita, PhD, is an Assistant Professor in the Department of Regenerative Medicine and Cell Biology at the Medical University of South Carolina (MUSC) College of Medicine. Her research focuses on molecular mechanisms controlling peripheral nervous system (PNS) development, particularly in heart innervation, enteric nervous system formation, and congenital disorders like Waardenburg-Shah syndrome. She employs mouse genetics, physiological assessments, and molecular biology to study signaling pathways in neural development. Education: B.S. in Chemistry, Tokyo Metropolitan University (1994) Ph.D. in Biochemistry and Molecular Biology, University of Southern California Keck School of Medicine (2004) Postdoctoral Fellowship at Johns Hopkins University (2005–2009) Research Interests: Molecular mechanisms of PNS circuitry, sympathetic axon guidance to the heart, enteric nervous system migration, and genetic loci contributing to congenital deafness. Current projects include investigating heart arrhythmia mechanisms, Waardenburg-Shah syndrome genetic screens, and sympathetic synapse formation in heart/kidney systems. Lab Work: Her lab uses mouse models and molecular approaches to dissect neural development pathways. Key collaborations include studies on cardiomyocyte regeneration, enteric neuron degeneration, and genetic therapies for lysosomal storage disorders.

Guilherme CostaView profile

Lecturer

• RNA Localization
• Angiogenesis
• Vascular Biology
• +3 more

Guilherme Costa is a Lecturer in Endothelial Biology at Queen’s University Belfast, UK, affiliated with the School of Medicine, Dentistry and Biomedical Sciences and the Wellcome Wolfson Institute for Experimental Medicine. His research focuses on spatial regulation of gene expression in endothelial cells, particularly mRNA localization and local protein synthesis in angiogenesis. He holds a PhD in Medical Sciences from the University of Manchester (2011) and is a Fellow of the Higher Education Academy. Research Interests: RNA localization and local protein synthesis in endothelial cells Angiogenesis mechanisms and vascular biology VEGF signaling and subcellular mRNA transport Recent Projects: R1688CEM: mRNA localisation as a subcellular target for pathological angiogenesis R2906CEM: Subcellular RNA localisation in blood vessel growth R8576CEM: Molecular mechanisms of eye/brain calcification Awards: Wellcome Trust Career Development Award (2022) Dean’s Prize for Early Career Research (2017) Labs/Teams: Costa Lab investigates RNA therapeutics and subcellular mechanisms in vascular biology, with a focus on endothelial cell modulation and translational medicine.

• Pediatric Oncology
• Stem Cell Biology
• Molecular Pathology
• +4 more

Miller Huang is an Assistant Professor of Pediatrics at the University of Southern California (USC), affiliated with Children’s Hospital Los Angeles. His research focuses on developing human pluripotent stem cell-based models to study pediatric cancers such as medulloblastoma and neuroblastoma. He investigates genetic drivers, therapeutic vulnerabilities, and signaling pathways involved in tumor initiation and progression. Education: Bachelor’s degree in Bioengineering from UC Berkeley PhD in Molecular Pathology from UC San Diego Research interests include modeling genetic predispositions in stem cells, identifying therapeutic targets, and understanding oncogenic pathways such as MYCN overexpression and EGFR-mediated metastasis. His work bridges basic science with translational applications, leveraging precision genome editing and stem cell engineering. Publications highlight advancements in stem cell-derived tumor models, molecular mechanisms of pediatric cancers, and signaling pathways like ALK/WNT and SHH. His studies often emphasize cooperative oncogenic interactions and vulnerabilities in cancer biology. Notable contributions include developing models for medulloblastoma and neuroblastoma, exploring N-Myc translational control, and dissecting EGFR/integrin signaling in metastasis. His research aims to translate these findings into clinical therapies for pediatric cancers.

Kimberlee GiffenView profile

Assistant Professor

• Neuroscience
• Regenerative Medicine
• Molecular Biology
• +3 more

Kimberlee Giffen is an Assistant Professor in the Department of Neuroscience and Regenerative Medicine at the Medical College of Georgia . Her academic work focuses on molecular mechanisms underlying sensory cell survival and degeneration. Ph.D. in Biomedical Sciences, Creighton University (2020) Master of Teaching, Grand Canyon University (2008) B.S. in Biology, University of Northern Colorado (2003) Research spans: Molecular profiling of cochlear aging Lysosomal dysfunction in auditory neuropathy Transcriptional regulation of inner ear development Evolutionary conservation of gene expression Publication trends reveal focus on auditory neuroscience, molecular pathology, and cross-species genetic analysis. Teaches graduate courses in clinical anatomy, renal/cardiopulmonary systems, GI/endocrinology, reproductive biology, and foundational medical sciences.

Andrea MünsterbergView profile

Professor

• Developmental Biology
• Embryonic Development
• Cell Fate Specification
• +14 more

Andrea Münsterberg is Professor of Developmental Biology in the School of Biological Sciences at the University of East Anglia (UEA). She leads a research group focused on the molecular and cellular mechanisms of embryonic development, particularly using chick embryos as a model system. Her work intersects with stem cell science and regenerative medicine, and she is a member of the Cells and Tissues research theme. She has held key administrative roles including Director of Research (2014–2017) and Theme Leader for Cells and Tissues (2010–2013). PhD, National Institute for Medical Research, MRC, Mill Hill, London (1992) German Diploma in Biology, University of Heidelberg (1988) Her research focuses on how cell fate decisions are regulated during vertebrate embryogenesis, especially in somite-derived tissues (muscle, bone, cartilage) and heart development. She investigates signaling pathways, cytoskeletal dynamics, microRNA function, and gene regulatory networks using molecular, genetic, and imaging techniques. Her group employs single-cell genomics and chromatin accessibility profiling to map developmental trajectories. The recent publications and active projects reveal a strong emphasis on transcriptional regulation, chromatin landscape analysis, cardiac progenitor biology, and somite patterning. Her work increasingly leverages cutting-edge technologies like single-cell RNA sequencing and spatial transcriptomics to understand developmental processes at high resolution. Collaborations with researchers such as G. Wheeler and S. Moxon highlight an interdisciplinary approach. Her scientific awards include prestigious fellowships from the Human Frontier Science Program Organization (HFSPO), Muscular Dystrophy Association (MDA), and the Wellcome Trust, all awarded competitively early in her career. She has supervised PhD students and postdoctoral researchers, welcoming applications from candidates seeking funding via fellowships (e.g., EU Marie Curie) or named postdoc positions on grants. She has secured significant research funding from the British Heart Foundation and the Biotechnology and Biological Sciences Research Council (BBSRC) for multiple projects investigating cardiac development, somite maturation, and gene regulation. She leads a dynamic, international research group that benefits from shared facilities such as the Henry Wellcome Bioimaging Lab and Taqman qPCR systems. The group collaborates closely with the Wheeler lab through joint lab meetings and co-led projects, and actively participates in the Cell and Developmental Biology seminar series and international conferences.

Steve MurrayView profile

Professor

• Developmental Biology
• Genetics
• CRISPR/Cas9
• +4 more

Steve Murray is a Professor and Senior Director at Genetic Resource Science , affiliated with the Graduate School of Biomedical Science and Engineering at the University of Maine. His research focuses on developmental mechanisms of morphogenesis and structural birth defects using CRISPR/Cas9 modeling, large-scale mutagenesis programs, and mouse genetic resources. Research Interests Murray's work spans: CRISPR/Cas9 for functional genomics Mouse models of human disease Embryonic morphogenesis and gene function Genetic drivers of behavioral and developmental traits Resource development for the scientific community His recent publications emphasize mouse mutagenesis programs (KOMP2), genome editing applications, and collaborations in developmental biology and immunology. Articles highlight interdisciplinary approaches to understanding genetic pathways, inflammation, and therapeutic interventions in rare disease models. Laboratory & Collaborations Murray leads initiatives at The Jackson Laboratory and contributes to international consortia like the International Mouse Phenotyping Consortium . His lab develops tools such as CrePortal.org for conditional mutagenesis and participates in large-scale phenotyping efforts.

• Virology
• RNA Biology
• MicroRNA Research
• +5 more

Nicolas Julien Fossat serves as an Associate Professor in the Department of Immunology and Microbiology at the Faculty of Health and Medical Sciences, University of Copenhagen. His research spans virology, RNA biology, and developmental biology with a particular focus on viral-host interactions and molecular mechanisms of disease. His research interests primarily focus on RNA biology and virology, with significant contributions to understanding viral RNA modifications, microRNA interactions in viral infections, and the molecular mechanisms of viral replication. His work on Hepatitis C virus RNA capping with flavin adenine dinucleotide represents a major discovery in the field of virology. Additionally, his research extends to developmental biology, particularly in understanding transcription factor networks like TWIST1 in cell differentiation processes. Analysis of his recent publications reveals a strong emphasis on RNA-virus interactions, particularly with flaviviruses including Hepatitis C, yellow fever, and tick-borne encephalitis viruses. His work on SARS-CoV-2 microRNA interactomes during the pandemic demonstrates his ability to pivot research toward emerging health threats. His publications in high-impact journals including Nature, Nature Communications, and Cell Reports highlight the significance of his contributions to the field. Fossat has established productive collaborations with prominent researchers including Bukh, Scheel, and Ramirez, resulting in multiple high-impact publications. His work has received substantial attention, with several papers being highlighted in news outlets and social media platforms, indicating the broader impact of his research.

David Jonah GrunwaldView profile

Professor

• Developmental Biology
• Genetics
• Stem Cell Biology
• +5 more

David Jonah Grunwald, Ph.D. is a Professor in the Department of Human Genetics at the University of Utah School of Medicine. His laboratory conducts research using zebrafish, mice, and human models to investigate fundamental mechanisms of tissue development, maintenance, and disease. With a career spanning several decades, Dr. Grunwald has established himself as a leading researcher in developmental genetics and genome editing techniques. Dr. Grunwald's research focuses on four primary themes: (1) molecular and genetic pathways regulating stem cell maintenance and differentiation, particularly examining how promoter proximal transcription pausing maintains multipotent precursor cells; (2) regulation of intracellular calcium mobilization in tissue development; (3) optimization of genome modification strategies in zebrafish to advance gene function studies; and (4) identification of pathways essential for joint homeostasis whose perturbation leads to osteoarthritis. His work bridges basic developmental mechanisms with translational applications in human disease. Analysis of Dr. Grunwald's recent publications reveals an evolving research trajectory from foundational zebrafish developmental studies to sophisticated genome editing techniques and disease mechanism investigations. His work demonstrates consistent focus on transcriptional regulation, calcium signaling, and stem cell biology, with increasing emphasis on osteoarthritis mechanisms in recent years. The publications show strong collaboration networks, particularly with Kazuyuki Hoshijima and Michael Jurynec, and demonstrate methodological progression from traditional mutagenesis to CRISPR-based approaches. Dr. Grunwald maintains an active research laboratory with multiple ongoing projects. His team includes senior research associates, undergraduate students, and likely graduate students and postdoctoral fellows, though specific trainee names aren't listed in the provided text. The laboratory appears well-supported by research grants enabling continued investigation into developmental mechanisms and disease models. The laboratory environment focuses on zebrafish as a primary model organism, with complementary work in mouse and human systems. Dr. Grunwald's team employs advanced techniques including CRISPR-Cas9 genome editing, calcium imaging, and molecular analysis of developmental pathways. The research has significant implications for understanding stem cell biology, tissue development, and osteoarthritis pathogenesis.

Helen MatthewsView profile

Research Fellow

• Cell Biology
• Cancer Biology
• Biophysics
• +3 more

Dr. Helen Matthews is a Research Fellow at the University of Sheffield's School of Biosciences, holding the Wellcome Trust/Royal Society Sir Henry Dale Fellowship since 2021. Her research focuses on understanding cell division mechanics in normal tissues and cancer, combining cell biology, microscopy, and biophysical techniques. She investigates how oncogenic signals alter cell shape and mechanics during mitosis, particularly in pancreatic cancer and tumor microenvironments. Matthews earned her MSci from Imperial College London (2000–2004) and a PhD from University College London (2004–2008), advised by Roberto Mayor. Postdoctoral work at the MRC Laboratory for Molecular Cell Biology (2009–2021) under Buzz Baum deepened her expertise in cell division mechanics. She also held visiting roles at Institut Curie (Paris) and the Francis Crick Institute. Her lab employs biophysical tools to study how mechanical forces influence cell division, including microfabrication to mimic tumor stiffness. Key areas include Ras-driven oncogenesis, epithelial tissue mechanics, and mitotic rounding dynamics. Recent work highlights Ras's role in disrupting cell-substrate interactions during division, impacting tumor formation. Awards: Wellcome Trust/Royal Society Sir Henry Dale Fellowship (2021–present) Labs/Teams: Based in the Molecular Cell Biology cluster at Sheffield, focusing on cancer cell mechanics and tumor microenvironment interactions.

• brain drug delivery
• blood-brain barrier modeling
• biopharmaceutical design
• +6 more

Eric Shusta is a Professor in the Department of Chemical and Biological Engineering at the University of Wisconsin-Madison, with additional affiliations to the Department of Biomedical Engineering. He is a leading expert in brain drug delivery, blood-brain barrier (BBB) modeling, and biopharmaceutical design, and has held prestigious roles including the R. Byron Bird Department Chair and Vilas Distinguished Achievement Professor. Education: PhD 1999, University of Illinois at Urbana-Champaign MS 1998, University of Illinois at Urbana-Champaign BS 1994, University of Wisconsin-Madison Research Focus: Shusta's research centers on overcoming the blood-brain barrier to enable non-invasive delivery of therapeutics to the brain. His lab employs molecular engineering, antibody discovery, and stem cell technologies to develop novel platforms for CNS drug delivery. A major thrust of his work involves creating accurate in vitro models of the BBB using human pluripotent stem cells, enabling high-throughput screening and disease modeling. His team has pioneered the use of yeast surface display to identify antibodies that target BBB transport systems and has developed stem cell-derived models to study neurovascular interactions in health and disease. These efforts bridge protein engineering, cellular biology, and translational neuroscience. Scientific Awards: R. Byron Bird Department Chair (2021) Vilas Distinguished Achievement Professor (2018) Howard Curler Distinguished Professor (2015) Fellow, American Institute for Medical and Biological Engineering (2014) NIH EUREKA Grant Award (2010) NSF CAREER Award (2003) Camille and Henry Dreyfus New Faculty Award (2001) Teaching & Mentorship: Shusta teaches graduate and undergraduate courses in chemical and biological engineering, including special topics in research methods and thesis advising. He also mentors students in biomedical engineering and molecular biology. Labs & Teams: He leads a multidisciplinary research group at UW-Madison that integrates protein engineering, stem cell biology, and neuropharmacology to address challenges in CNS therapeutics. His lab collaborates with clinical and translational researchers to advance brain-targeted therapies.

Anna Sartori-RuppView profile

Researcher

• Structural Biology
• Bioimage Analysis
• Cryo-Electron Microscopy
• +2 more

Anna Sartori-Rupp is an Expert Research Engineer at the NanoImaging Core Facility of the Institut Pasteur (since 2022). Previously, she worked as a Research Engineer at the Ultrastructural BioImaging Unit (2007-2022) and as a Visiting Scientist at the LBME lab (Toulouse, 2014-2016). She completed postdoctoral fellowships at the Max Planck Institute of Biochemistry (Munich, 2004-2007) and Institut Curie (Paris, 2001-2004), following her PhD in Mathematical Physics at Imperial College London (1998-2001). Education: Master in Physics (University of Padua, 1991-1997); Erasmus exchange at Imperial College London (1995-1996) Research Interests focus on technological development for cryo-correlative light and electron microscopy (cryo-CLEM) , enabling 3D imaging of cellular systems. Her work bridges structural biology and host-pathogen interactions , with key contributions to super-resolution cryo-CLEM pipelines and cryo-FIB for lamellae preparation . She collaborates extensively with labs studying neuronal tunneling nanotubes (Zurzolo), HIV-1 envelope conformations (Sansonetti), and bacterial cell envelope evolution (Gribaldo). Scientific Contributions include: Developing the first cryo-CLEM method to visualize actin organization in neuronal tunneling nanotubes Pioneering 3D cryo-CLEM workflows at Institut Pasteur's advanced facilities (Titan Krios, Aquilos2 cryo-FIB) Organizing the IPEMtomo image processing courses (2021-2025) Awards : Marie Curie Individual Fellowship Collaborations span institutions in France (Institut Pasteur, LBME Toulouse), Germany (MPI Biochemistry, Charité Berlin), and international partners via EU-funded projects like CLEXM and ENVOL .