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Andrew Holle is an Assistant Professor at the Mechanobiology Institute , National University of Singapore , where he leads the Confinement Mechanobiology Lab within the Department of Biomedical Engineering . His work spans mechanobiology, stem cell differentiation, cancer mechanobiology, and microfluidics, with a focus on understanding how physical confinement influences cellular behavior. Education: B.S.E. in Bioengineering (Minor in Statistics), Arizona State University (2008) Ph.D. in Bioengineering, University of California San Diego (2013) Research in the Confinement Mechanobiology Lab centers on the hypothesis that stem cell differentiation is driven by mechanical cues during migration through confined extracellular matrix (ECM) environments. The lab develops microfluidic systems to mimic ECM confinement and studies its impact on osteogenic differentiation , cancer cell migration , and cellular condensates . Recent publications highlight interdisciplinary approaches combining mechanobiology , nanotechnology , and microfluidics to explore nuclear morphological changes, volume regulation, and ligand signaling in confined cellular environments. Laboratory Members: Privita Edwina (Research Fellow) Vaishnavi Rangaraj (Research Assistant) Sriram Muthukumar (Research Fellow) Chang Ye Ji (PhD Student) Gao Xu (PhD Student) Lim Yuan Bin (PhD Student) Shinny Sunny (PhD Student) Lee Jia Wen Nicole (PhD Student) Li Yixuan (PhD Student)

• Mechanobiology
• Stem Cell Differentiation
• Cancer Mechanobiology
• +3 more

Vivek Shenoy is the Eduardo D. Glandt President's Distinguished Professor at the University of Pennsylvania, with primary appointments in the Department of Materials Science and Engineering and secondary appointments in Bioengineering and Mechanical Engineering and Applied Mechanics. He leads the Multiscale Mechanobiology and Biomaterials Laboratory, which focuses on developing theoretical frameworks and numerical methods to understand complex biological and engineering systems across multiple length scales. Shenoy's research spans mechanobiology, chromatin organization, cell mechanics, and biomaterials. His work addresses the fundamental challenge of modeling how small-scale cellular phenomena couple with long-range tissue-level interactions across micrometers to centimeters. By integrating insights from soft matter physics, solid mechanics, chemistry, and applied mathematics, his group develops multiphysics continuum and mesoscale theories to elucidate mechanisms controlling both biological and engineering systems. His recent publications demonstrate an increasing focus on nuclear mechanics, chromatin organization, and the interplay between mechanical forces and gene regulation. Analysis of Shenoy's publication record reveals a strong interdisciplinary approach, with high-impact papers spanning biophysics, materials science, and cell biology. His work shows consistent evolution from fundamental mechanics of materials to complex biological systems, with recent emphasis on the mechanical regulation of chromatin architecture, cell migration dynamics in 3D environments, and mechanotransduction in development and disease. His publications appear regularly in top journals including Nature, Science, and their affiliated publications, demonstrating significant influence across multiple fields. Eduardo D. Glandt President's Distinguished Professor Multiple publications in Nature, Science, and PNAS Active research program with publications through 2025 Shenoy actively mentors students and postdocs through his laboratory, with numerous co-authored publications indicating strong mentorship. His research program appears to be well-funded through multiple grants supporting his work in mechanobiology and biomaterials. The Multiscale Mechanobiology and Biomaterials Laboratory maintains active collaborations across disciplines and institutions, reflecting the interdisciplinary nature of his research. The Multiscale Mechanobiology and Biomaterials Laboratory, housed within the Department of Materials Science and Engineering at the University of Pennsylvania, serves as the primary research hub for Shenoy's work. The lab maintains an active presence on social media (Twitter: @ShenoyLab) for updates on activities and publications. Their research approach combines theoretical modeling with experimental validation to address fundamental questions at the interface of mechanics, materials science, and biology.

• Mechanobiology
• Multiscale Modeling
• Biomaterials
• +6 more

Michael McAlpine is a Professor in the Mechanical Engineering department at the University of Minnesota . He also holds affiliations with the Biomedical Engineering and Electrical and Computer Engineering departments. His research focuses on 3D printing functional materials & devices , Nanoscale inks , Biomedical devices , Bioelectronics , and Flexible Microsystems . Research Interests : 3D Printing, Biomedical Engineering, Nanotechnology, Flexible Electronics, Microfluidics Labs : ME 361/363 Contact : mcalpine@umn.edu , (612) 626-3303, ME 117 Recent Research Trends include 3D Printed Biomedical Devices , Flexible Electronics , and Bioprinting Applications . His work spans from Spinal Organoid Formation to Programmable Drug Release Capsules . Scientific Award : Circulation Research 2020 Best Manuscript Award

• 3D Printing
• Nanotechnology
• Biomedical Engineering
• +4 more

James A. Evans is a Professor at the University of Chicago, where he serves as Director of the Knowledge Lab and Faculty Director of the Masters Program in Computational Social Science. He is also an External Professor at the Santa Fe Institute. His research bridges computational methods with social theory to analyze collective cognition, innovation, and knowledge production across science, technology, and broader societal domains. Director, Knowledge Lab Faculty Director, Masters Program in Computational Social Science External Professor, Santa Fe Institute Evans’s research explores how social and technical institutions shape discovery processes, utilizing machine learning, network modeling, and large-scale data analysis. His work spans fields like computational social science, sociology of science, and data science, focusing on team dynamics, peer review, and the global structure of scholarship. His recent publications examine team size effects on innovation, discursive influence in academia, and the interplay between tradition and novelty in research strategies. Articles trend toward interdisciplinary approaches combining social theory, computational methods, and science policy. Evans supports novel observatories for human understanding through crowdsourcing, sensor networks, and semantic modeling. He has received funding from the National Science Foundation, National Institutes of Health, and Air Force Office of Scientific Research, with findings featured in major media outlets like Nature , Science , and The New York Times .

• Computational Social Science
• Collective Cognition
• Innovation Studies
• +12 more

Zhe Ji is an Assistant Professor in the Department of Biomedical Engineering at McCormick School of Engineering and the Department of Pharmacology at Feinberg School of Medicine, Northwestern University. His research integrates computational and experimental genomics to study gene transcription and RNA translation in cell fate commitment and oncogenic processes, aiming to develop precision medicine strategies. **Education**: Postdoctoral Fellow in Cancer Systems Biology, Harvard Medical School Postdoctoral Fellow in Computational Biology, Broad Institute of MIT and Harvard Ph.D. in Computational Genomics, Rutgers University B.S. in Biotechnology, Nanjing University, China **Research Focus**: Keywords include Data Science, Computational Biology, Functional Genomics, RNA, Cancer, Inflammation, and Machine Learning. The lab explores regulatory mechanisms underlying disease, with a focus on translational control, cancer metastasis, and inflammatory networks. **Grants & Advising**: No specific grants or student advisees listed. The lab emphasizes collaborative projects and computational-experimental approaches. **Lab Affiliations**: Zhe Ji’s lab is part of Northwestern’s interdisciplinary environment, bridging engineering and medicine to advance genomic technologies and therapeutic strategies.

• Data Science
• Computational Biology
• Functional Genomics
• +4 more

Prof. Waldemar Kolanus leads the Molecular Immunology and Cell Biology department at the University of Bonn's Life & Medical Sciences Institute (LIMES) . His research bridges immunoregulation , stem cell dynamics , and metabolic stress responses in immune cells. Unit 2 member at LIMES Principal investigator in SFB 704 and ImmunoSensation Cluster Leads a multidisciplinary lab with postdocs, PhD students, and technical staff His work focuses on intracellular signaling pathways connecting immune activation to tissue homeostasis, particularly through: Cytohesin proteins in integrin-mediated adhesion and migration TRIM71 in stem cell regulation and congenital hydrocephalus High-salt environments affecting macrophage function Publication trends show expertise in immune cell migration , genetic models , and chemical inhibition , with frequent use of mice and zebrafish for in vivo studies. Key articles explore: TRIM71's dual role in auditory development and germ cell maintenance Cytohesin family's Golgi regulation and insulin signaling Ruxolitinib's off-target migration inhibition of dendritic cells Contact details: Address: LIMES Institute, Carl-Troll-Straße 31, Bonn Email: kolanus.sekretariat@uni-bonn.de Phone: +49 228 73-62788

• Molecular Immunology
• Cell Signaling
• Signal Transduction Pathways
• +4 more

Chao Liu is an Associate Professor at the Department of Biomedical Engineering , Southern University of Science and Technology (2024.11–present). Previously, he served as an Assistant Professor at the same institution (2019–2024.11) and completed a Postdoctoral Fellowship at New York University (2016–2019) with joint appointments in the Department of Biomedical Engineering and Orthopedics at NYU Langone Health . He holds a PhD in Biomedical Engineering (2016) and MASc in Mechanical Engineering (2010) from University of Toronto , following a BASc in Engineering Science (2008). Education : PhD (IBBME, U of Toronto, 2016), MASc (Mechanical Engineering, U of Toronto, 2010), BASc (Engineering Science, U of Toronto, 2008) His research focuses on mechanobiology of stem cells , bone tissue engineering , and functional implants . He investigates how mechanical forces modulate osteogenic and angiogenic stem cells, designs implants with micro-geometry to enhance cellular activity, and develops 3D real-time imaging modalities for bone repair processes. His work spans biomechanics , regenerative medicine , and cellular mechanotransduction . The selected publications from 2022 to 2010 reveal trends in mechanical force applications for bone regeneration, pharmacological impairments in healing, nanostructured biomaterials for stem cell differentiation, and microfluidic platforms for osteocyte studies. These works are published in journals like Bone , FASEB Journal , and ACS Applied Materials & Interfaces . Scientific Awards : International Conference BME Young Investigator Award (2019), IFMRS Travel Grant (2017), ASBMR Young Investigator Grant (2016), CIHR Travel Awards (2010–2014), Ontario Graduate Scholarship (2011–2013), Barbara and Frank Milligan Fellowship (2008, 2010) Chao Liu mentors graduate students, including Zhang Jianing (2022 Master’s graduate). His lab ( https://abtrl.bme.sustech.edu.cn/ ) recruits postdocs and research assistants for projects in mechanical force applications , micro-geometric implants , and 3D imaging . He has contributed to 14 journal articles with 714 citations and presented at 6 international conferences in the past three years.

• Stem Cell Mechanobiology
• Bone Tissue Engineering
• Regenerative Medicine
• +3 more

Nonappa Nonappa is an Associate Professor (tenure track) in Nanochemistry at Tampere University's Faculty of Engineering and Natural Sciences since 2020. With a multidisciplinary background spanning organic chemistry, supramolecular systems, nanoparticle self-assembly, and advanced electron microscopy, he leads research at the intersection of materials science and biomedical applications. PhD in Organic Chemistry (IISc Bangalore, 2008) Docent in Soft Matter Microscopy (Aalto University, 2017) Executive MBA (Quantic School, 2020) Research focuses on bio-based optical materials using nanocellulose for sustainable photonics, breast cancer models via lab-on-a-chip systems, and precision nanomaterials through tailored self-assembly mechanisms. His team develops 3D extracellular matrices for cancer tissue culture and plasmonic nanodevices for photonic applications. Recent publications highlight gold/silver nanocluster assemblies (43+ citations in 2021-2025), electron tomography for structural analysis, and metastasis modeling systems. Key awards include Italy's Abilitazione Scientifica Nazionale (2018) and Aalto University's Docent title (2017).

• Nanochemistry
• Material Chemistry
• Biobased Optics and Photonics
• +7 more

Dr. Yi Shen is a Senior Lecturer at the School of Chemical and Biomolecular Engineering, The University of Sydney, and Chair of RACI Women in Chemistry. She is also affiliated with multiple research institutes including Sydney Institute of Agriculture, Sydney Southeast Asia Centre, The Centre for Drug Discovery Innovation, and The University of Sydney Nano Institute. PhD in Soft Materials from ETH Zurich Postdoctoral research at University of Cambridge and Harvard University Her research focuses on protein phase behavior and functional biomaterials development, utilizing soft matter approaches and microfluidic techniques to address challenges in neurodegenerative diseases, sustainable materials, and biomedical engineering. She has published extensively in top journals like Nature Nanotechnology and PNAS, with a particular emphasis on: Protein liquid-liquid phase separation mechanisms Biomaterials from protein nanofibrils Microfluidic manipulation of biological systems Biodegradable bioplastics development Shear force effects on biomolecular systems Pathological protein aggregation dynamics Key scientific achievements include: 2022 ARC DECRA Fellowship 2022 Sydney Nano Frontier award 2018 ETH Zurich Spark Award (for Fe delivery system invention) 2012 Princeton Grand Challenges Program 2 patents pending 2 Nature Nanotechnology cover articles As an educator, she coordinates CHNG2802 Chemical Engineering Modelling and Analysis, co-teaches CHNG3804 Biochemical Engineering and CHNG5605 Bio-products: Laboratory to Marketplace, and guest lectures across biomedical and nanotechnology programs. Her lab actively collaborates with institutions in Switzerland (ETH Zurich), UK (Cambridge), and US (Harvard, Princeton), focusing on transforming biomolecular understanding into real-world applications in health, industry, and environmental sustainability.

• Protein Biophysics
• Soft Materials
• Microfluidics
• +5 more

Ovijit Chaudhuri is an Associate Professor of Mechanical Engineering at Stanford University, with a courtesy appointment in Bioengineering. He leads research at the interface of mechanics and biology, focusing on how cellular and extracellular mechanical properties influence biological processes like cancer progression and tissue formation. His work employs advanced tools such as atomic force microscopy and 3D cell culture systems. Education: Ph.D., University of California, Berkeley/San Francisco (Bioengineering, 2009) B.S., University of California, Berkeley (Engineering Physics, 2003) Postdoctoral Fellow, Harvard University (Biomaterials, 2013) Research Interests: His lab explores molecular mechanisms behind cellular mechanics, extracellular matrix dynamics, and how mechanical cues regulate cell behavior. Key areas include cancer metastasis, mechanotransduction, and engineered biomaterials for 3D cell culture. Publications Trends: Recent work emphasizes viscoelastic hydrogels, matrix mechanics in cancer progression, and mechanistic insights into cell migration. Over 50 publications since 2015 highlight interdisciplinary approaches in biomaterials and mechanobiology. Awards: Not explicitly listed in provided materials. Advising & Labs: No specific advisee names listed, but his lab focuses on collaborative projects in mechano-biology. Active in developing biomaterial systems for drug discovery and tissue engineering applications. Labs/Teams: Leads the Chaudhuri Lab at Stanford, which integrates engineering principles with biological systems to address complex disease mechanisms and therapeutic strategies.

• Mechanobiology
• Cellular Mechanics
• Extracellular Matrix
• +5 more

Lin He is the Thomas and Stacey Siebel Distinguished Chair in Stem Cell Research and Professor of Cell Biology and Physiology at the University of California, Berkeley. His laboratory focuses on understanding the biological functions of non-coding RNAs in development and disease, with particular emphasis on microRNAs (miRNAs) in cancer, stem cell biology, and developmental processes. He developed the CRISPR-EZ method for highly efficient mouse genome editing, significantly advancing genetic research. Research interests include miRNAs' roles in tumor progression, metastasis, and pluripotency regulation in stem cells. His work bridges mouse genetics, genomics, and molecular biology to uncover mechanisms governing non-coding RNA functions. Current projects address miRNAs in oncogenesis, stem cell fate determination, and the interplay between non-coding RNAs and retrotransposons in development. Key contributions include identifying miRNA networks in cancer pathways, demonstrating miRNA requirements for ciliogenesis and lung development, and advancing CRISPR-based genome editing techniques. His interdisciplinary approach integrates genetic, genomic, and cellular tools to explore fundamental questions in biology and medicine. Lab website: helabucb.org CRISPR-EZ technology enables 100% genome editing efficiency in mouse zygotes Pioneering studies on miRNA regulation of PTEN, p53, and oncogene pathways

• Non-coding RNA Research
• Cancer Biology
• Stem Cell Biology
• +3 more

Hsueh-Chia Chang is the Bayer Professor of Chemical Engineering in the Department of Chemical and Biomolecular Engineering at the University of Notre Dame's College of Engineering. He also holds a concurrent faculty position in the Department of Aerospace and Mechanical Engineering. As Principal Investigator of the Chang Lab, he leads cutting-edge research in microfluidic and nanofluidic technologies for biomedical applications. Prof. Chang received his B.S. in Chemical Engineering from Caltech in 1976, followed by M.S. and Ph.D. degrees in Chemical Engineering from Princeton University in 1977 and 1980, respectively. His academic journey has established him as a leader in the field of microfluidics and biosensing technologies. Chang's research focuses on developing low-cost liquid biopsy nanotechnologies for cancer screening and therapy management. His lab specializes in microfluidic and nanofluidic research coupled with electrokinetics, optics, plasmonics and acoustics for biosensing applications. Key research areas include Electrokinetics & Biosensing, Optics & Plasmonics, Nanoelectrokinetics, and Droplet Microfluidics. The Chang Lab has developed innovative platforms that can isolate and sort tumor cells, exosomes, microvesicles, lipoproteins, and stress granules from blood samples, then lyse these structures to release RNA/protein biomarkers for detection and quantification. His recent publications reveal a strong focus on extracellular vesicle diagnostics, cancer biomarker detection, and point-of-care diagnostic technologies. The research spans multiple disciplines including oncology, cardiology, and neurology, with applications for pancreatic, liver, breast, ovarian, and lung cancers as well as myocardial infarction diagnosis. Fellow of American Institute of Medical and Biological Engineering (2025) Provost Research Achievement Award, Notre Dame (2024) Fellow of the National Academy of Inventors (2020) Lifetime Achievement Award, American Electrophoresis Society (2019) Fellow of the American Physical Society (1997) Presidential Young Investigator Award, NSF (1985) Prof. Chang has advised over 50 PhD students and postdocs who have gone on to prominent positions in academia and industry. His lab has secured significant funding and has commercialized several technologies through startups like Aopia Biosciences, which launched NanoEx at ISEV 2024. The Chang Lab maintains active collaborations with medical researchers for validating their diagnostic platforms against various cancers and cardiac conditions.

• Microfluidics
• Nanofluidics
• Electrokinetics
• +5 more

Michael Levin is a Vannevar Bush Professor and Distinguished Professor at Tufts University, affiliated with the School of Arts and Sciences (Department of Biology) and School of Engineering (Biomedical Engineering). His research focuses on bioelectricity, developmental biology, and collective intelligence. He leads the Allen Discovery Center and the Tufts Center for Developmental and Regenerative Biology. Education: PhD in Genetics from Harvard Medical School (1996); BS in Computer Science and Biology from Tufts University (1992). Research Interests: Integrates developmental biology, computer science, and cognitive science to study morphogenesis, regeneration, and cancer. Explores bioelectric signaling, synthetic organisms, and AI-driven discovery. Key areas include regenerative medicine, cancer reprogramming, and collective intelligence in biological systems. Publications: Over 600 articles, with recent work on xenobots, neuroevolution, and bioelectric therapies. Themes include bioelectric control of form, AI in biology, and collective intelligence. Awards: INNS Donald O. Hebb Award, AAAS Fellow, and Vox Future Perfect 50 List recognition. Frequently invited to speak at conferences on biology, AI, and consciousness. Advising & Labs: Mentored numerous postdocs and students, including pioneers in bioelectricity and synthetic biology. Lab focuses on interdisciplinary approaches to biological pattern formation and regeneration.

• Bioelectricity
• Regenerative Medicine
• Cancer Biology
• +5 more

Jennifer L. West is the Dean of the University of Virginia School of Engineering and Applied Science and holds the Saunders Family Professorship in Engineering. She is a dual professor in Biomedical Engineering and Mechanical and Aerospace Engineering. Dean West has a 30-year record as a researcher, educator, inventor, and entrepreneur, focusing on biomaterials, nanotechnology, and tissue engineering to address unmet medical needs, particularly in cancer therapy. Her education includes a B.S. from MIT (1992) and a Ph.D. from the University of Texas at Austin (1996). Before UVA, she was at Duke University as the Fitzpatrick Family Distinguished Professor of Engineering and Associate Dean for Ph.D. Education. Research Interests: Biomaterials and biosynthesis Nanotechnology and tissue engineering Cancer therapy through engineered materials Scientific Awards: Member of the National Academy of Medicine (2023) Member of the National Academy of Engineering (2016) Over 20 patents, including foundational work for Nanospectra Biosciences’ clinical trials in cancer therapy Grants & Initiatives: Leading UVA Engineering’s focus on research, experiential learning, and entrepreneurship Recipient of a $900,000 grant for character-building education initiatives Labs & Teams: Developed hydrogel platforms for tissue integration, vascularization, and drug delivery Pioneered gold nanoshell-based photothermal cancer therapy

• Biomaterials
• Nanotechnology
• Tissue Engineering
• +3 more

Amy Catherine Rowat is a full Professor in the Department of Integrative Biology and Physiology at UCLA's College of Letters and Science. She directs an interdisciplinary research program that integrates mechanobiology, microfluidics, cancer biophysics and food engineering to understand how physical forces shape cell behavior and to develop sustainable biotechnologies. Education & Affiliations: Professor, Department of Integrative Biology and Physiology, UCLA Member, UCLA College of Letters and Science Research Interests: Rowat's group deciphers how mechanical properties of cells and their nuclei influence disease progression and therapeutic response. Using high-throughput microfluidic deformability cytometry, her team discovered that cancer cells become stiffer and more invasive upon β-adrenergic signaling, linking stress hormones to metastatic potential. Parallel efforts focus on nuclear envelope mechanics, showing that histone H1.0 and transient nuclear deformation modulate chromatin structure and cell reprogramming. Beyond biomedicine, Rowat pioneers biophysical approaches for sustainable food production. She engineers edible scaffolds and emulsion-templated microcarriers to culture meat at scale, demonstrating spontaneous fusion of adipogenic and myogenic microtissues into marbled steak-like constructs. Recent Article Trends (2020-2025): Her latest publications reveal a cohesive trajectory: coupling mechanobiology to epigenetic regulation (viscoelastic matrix enhances chromatin remodeling), advancing single-cell mechanical phenotyping (optomagnetic arrays, high-throughput screens), translating findings to cancer therapy (β-blockers to sensitize chemotherapy) and expanding engineered foods (scalable cultured-meat bioprocessing). Funding & Awards: NIH R21 CA245667 (PI) – Repurposing beta-blockers to improve chemotherapy response (2021-2023) Laboratory & Teams: Rowat leads an active research laboratory at UCLA that trains graduate students and postdocs at the intersection of physics, engineering and biology. The lab maintains collaborations across UCLA Engineering, Jonsson Comprehensive Cancer Center, and external partners in food science and biotechnology companies.

• Mechanobiology
• Cancer biophysics
• Single-cell mechanics
• +6 more