Find Academic Supervisors

• Molecular Cell Biology
• Signal Transduction
• Gene Expression Regulation
• +5 more

Shim Jae-kyung serves as Assistant Professor in the Department of Bioindustry and Resource Engineering at Sejong University's School of Life Systems, where she has conducted research since 2015 following her prior appointment in the Department of Molecular Biology (2003-2014). Her work centers on nuclear signaling mechanisms and disease pathogenesis. Her academic foundation includes: Ph.D. in Biological Science from Korea Advanced Institute of Science and Technology (2000) M.S. in Biochemistry from Yonsei University (1994) B.S. in Biochemistry from Yonsei University (1991) Research focuses on nuclear signal transduction and gene expression regulation , particularly examining Notch/STAT3 pathway crosstalk , nuclear membrane protein functions (Emerin), and RNA modification mechanisms (YTHDF2). Her laboratory employs zebrafish developmental models , mammalian cell systems , and plant stress response studies to investigate disease mechanisms including cancer progression and developmental disorders. Current work reveals how spatial control of signaling molecules at the nuclear membrane regulates transcriptional outcomes. Publication analysis shows consistent emphasis on nuclear signaling hubs since 2014, with recent work (2021-2024) demonstrating triptolide's dual regulation of Notch/STAT3 in cancer and development, Emerin's spatial control of STAT3, and YTHDF2's post-transcriptional regulation of Notch. Plant research complements this through stress response mechanisms in crops. Professor Shim leads the Molecular and Cellular Biology Laboratory (Chung1127), supervising master's thesis research while teaching courses including General Biochemistry, Biopolymer Engineering, and Antibody Engineering. Her consultation hours are Monday, Wednesday, and Friday 3:00-5:00 PM.

• Epitranscriptomics
• RNA Biology
• Ribozymes
• +4 more

Henrik Nielsen is a Professor with special responsibilities at the University of Copenhagen's Department of Cellular and Molecular Medicine, where he leads research in the Transcription, RNA, and Gene Medicine Program. His academic journey includes a Master's (1983) and PhD (1990) in Molecular Biology from the University of Copenhagen. He has held progressive academic positions since 1984, including Associate Professorships at the University of Copenhagen and University of Tromsø, before attaining his current professorship. His research focuses on RNA biology with emphasis on: Epitranscriptomics and specialized ribosomes in immune function, development, and cancer Catalytic RNA mechanisms including ribozymes and splicing RNA-guided nucleotide modifications and helicase functions Novel RNA cap structures and lariat capping ribozymes Recent publications (2021-2024) demonstrate strong focus on ribosomal RNA modifications, ribosome heterogeneity, and their functional impacts across biological systems including skeletal muscle, stem cells, and microbial organisms. The work consistently integrates molecular biology with physiological contexts. Awards include: Teacher of the Year 1998 from the Health Science Faculty He leads the H Nielsen research group and maintains active collaborations through networks including InnControl (Norwegian Research Council) and COST Translacore. Key collaborators span institutions in Copenhagen, Göttingen, Toulouse, and Stockholm.

Ciprian P. GheorgheView profile

Assistant Professor

• Obstetrics and Gynecology
• Maternal-Fetal Medicine
• Placental Biology
• +4 more

Ciprian P. Gheorghe, MD, PhD, serves as Assistant Professor in both the Department of Gynecology and Obstetrics and the Physiology Division of Basic Sciences at Loma Linda University School of Medicine, where he conducts interdisciplinary research bridging obstetrics, physiology, and molecular medicine. His academic credentials include: Doctor of Medicine (MD) from Loma Linda University (2008) Doctor of Philosophy (PhD) from Loma Linda University (2006) Dr. Gheorghe's research centers on maternal-fetal medicine with emphasis on environmental impacts on fetal development, placental molecular pathways, and innovative interventions. Key areas include wildfire exposure effects on congenital heart defects, gestational hypoxia-induced pulmonary remodeling, nitric oxide signaling in placental iron metabolism, and molecular mechanisms of glucocorticoid response in preterm newborns. His work integrates multi-omics approaches and translational models to address critical perinatal complications. Analysis of his 2021-2025 publications reveals consistent themes in perinatal pathophysiology, with growing focus on environmental stressors (wildfires, hypoxia) and molecular mechanisms (exosomal miRNAs, epitranscriptomics). His recent work demonstrates increasing collaboration with virology and genomics teams, particularly regarding SARS-CoV-2 pathogenesis and therapeutic development. Dr. Gheorghe actively mentors graduate students through his extensive grant portfolio, which includes NIH-funded projects on umbilical cord milking (NICHD 2024-2025), gastroschisis outcomes (MCW 2020-2023), and vertical SARS-CoV-2 transmission. His $1.2M+ in active funding spans federal, industry (Karl Storz, Alydia Health), and institutional sources, supporting both clinical trials and basic science investigations into fetal programming and placental dysfunction. His research operates within Loma Linda University's Center for Perinatal Biology and the Charles and Nancy Sims Institute for Genetics & Translational Genomics Research, where he directs the BioBank and Database project. These resources enable longitudinal studies of gastroschisis, TTTS, and placental biomarkers through integrated clinical and molecular analytics.

Mridusmita SaikiaView profile

Lecturer

• Biomedical Engineering
• Molecular Biology
• Genomics
• +3 more

Dr. Mridusmita Saikia is a Lecturer at the Meinig School of Biomedical Engineering, Cornell University, since 2020. Her research focuses on biomedical engineering, biomolecular engineering, and molecular and cellular engineering, with expertise in RNA modifications, diabetes pathogenesis, and single-cell RNA sequencing. She teaches courses in Cellular and Molecular Engineering, emphasizing foundational concepts applicable to biomedical innovations. Education includes a B.Sc. (Chemistry, St. Stephen’s College, University of Delhi, 2002), M.Sc. (Chemistry, IIT Delhi, 2004), M.S. (Chemistry, University of Chicago, 2005), and Ph.D. (Chemistry, University of Chicago, 2009). Postdoctoral research was conducted at Case Western Reserve University and Cornell University. Her research explores non-coding RNAs and their roles in gene expression, with recent work on immune cell function and pancreatic beta-cell pathology linked to diabetes. She employs single-cell sequencing and molecular engineering techniques to advance understanding of cellular mechanisms in health and disease. Awards: Robert & Vanne Cowie Teaching Award (2022), CRISTEL Award (2022–2023), Prodo Labs Best Talk Award (2020), and multiple fellowships including the Burroughs Wellcome Fellowship (2005–2006). Teaching includes courses like BME 2010 (Physiology of Health/Disease), BME 3010 (Cellular Principles), and BME 5830 (Cell-Biomaterial Interactions). Her pedagogy aims to bridge foundational concepts with clinical and engineering applications. Research outputs span diabetes mechanisms, RNA stress responses, and single-cell profiling. Collaborations include studies on GLP-1 receptor signaling, beta-cell differentiation, and tiRNA functions in apoptosis.

• Radiation Effects in Microelectronics
• Radiation Tolerant Circuits
• Fault Tolerant Neural Networks
• +2 more

Professor Li Chen holds dual appointments in Electrical and Computer Engineering and Biomedical Engineering at the University of Saskatchewan's College of Engineering. His research develops radiation-hardened electronics and reliable computing systems for critical applications. Holds BSc in Electrical Engineering, MEng, and PhD degrees. Professional engineering license (P.Eng.) indicates certified expertise. Research focuses on radiation effects in microelectronics, fault-tolerant circuit design, neural network reliability, silicon device reliability, and biomedical sensors. Current projects include radiation hardening techniques for advanced nodes, single-event effect characterization, and photonic biosensors. Publications demonstrate innovations in radiation-hardened flip-flop designs, SEE characterization methodologies, and applications of machine learning in bioinformatics and reliability engineering. Recent work includes photonic biosensors for virus detection and federated learning for genomic analysis. No scientific awards reported in source materials Leads research at Radiation Effects Research Laboratory, focusing on semiconductor reliability under radiation exposure. Collaborations include industry partners in aerospace and medical device sectors. No specific student advising details available in provided text

Huiqing ZhouView profile

Assistant Professor

• Epitranscriptomics
• RNA Modifications
• Nucleic Acid Chemistry
• +4 more

Huiqing (Jane) Zhou is an Assistant Professor of Chemistry at Boston College, affiliated with the Morrissey College of Arts and Sciences and the Chemistry Department. Her research focuses on developing technologies to map and modulate RNA chemical modifications (epitranscriptome) in mammalian systems. She employs interdisciplinary approaches including directed evolution, biochemistry, mass spectrometry, and structural biology to study the regulatory mechanisms of these modifications in gene expression and disease. Education: B.S., Nankai University Ph.D., Duke University Research Interests: Her lab explores how RNA modifications influence transcript stability, interactions, and expression, with applications in disease modeling and gene therapy. Key areas include base-resolution mapping of modifications, engineering tools for modification manipulation, and understanding dysregulated epitranscriptomes in diseases like Alzheimer’s. Publications: Her work spans publications in Nature Methods , Biochemistry , and Nucleic Acids Research , focusing on reverse transcriptase evolution, Hoogsteen base pairing dynamics, and RNA modification detection technologies. Awards: 2017 Chicago Fellows Fellowship. Lab & Funding: Supported by Boston College and grants from the National Institutes of Health (NIGMS, NCI). Her lab develops cutting-edge tools to visualize and modulate RNA modifications, aiming to identify novel drug targets and advance gene therapy strategies.

Christian HennebergerView profile

Professor

• Neuroscience
• Neurobiology
• Neuron-Glia Interaction
• +7 more

Prof. Christian Henneberger is a Professor at the Institute of Cellular Neurosciences, Medical Faculty, University of Bonn. His research focuses on neuron-glia interactions, brain plasticity, and synaptic transmission, particularly exploring astrocyte roles in hippocampal network function, disease mechanisms, and signaling dynamics using advanced techniques like electrophysiology and two-photon microscopy. He leads the Synaptic and glial plasticity lab, collaborating with international networks such as NeurotechEU and the Bonn Center for Neuroscience. His research integrates experimental methods with computational modeling (e.g., NEURON simulations) to study astrocyte morphology changes, glutamate signaling, and glycine/D-serine co-agonist dynamics. Key projects include understanding astrocyte withdrawal during synaptic potentiation, calcium signaling regulation, and the impact of metabolic stress on neurotransmitter homeostasis. The lab actively mentors PhD and MD students, with notable advisees including Kirsten Bohmbach (PhD 2021) and Björn Breithausen (PhD 2020). Publications highlight breakthroughs like the discovery of astrocyte-driven glutamate spillover during long-term potentiation and the development of optical sensors (e.g., GlyFS for glycine monitoring). His work bridges cellular mechanisms to cognitive functions, addressing epilepsy, Alzheimer’s disease, and neurodevelopmental disorders through glial-neuronal crosstalk. Labs/Teams: Synaptic and glial plasticity lab (Bonn), Bonn Center for Neuroscience, NeurotechEU (European alliance for brain research), and collaborations with institutions like the Australian National University and RWTH Aachen.

Trever BivonaView profile

Professor

• Cancer Biology
• Signal Transduction
• Cancer Genetics
• +12 more

Trever Bivona, MD, PhD, is a Professor in the Department of Medicine and the Department of Cellular and Molecular Pharmacology at the University of California, San Francisco (UCSF) School of Medicine. He is a physician-scientist and cancer biologist whose research focuses on signal transduction, tumor evolution, and drug resistance in lung cancer. Dr. Bivona earned his MD and PhD in Cell and Molecular Biology from New York University School of Medicine, completed residency in Internal Medicine at Brigham and Women's Hospital/Harvard, and pursued postdoctoral training in Medical Oncology and Cancer Biology at Memorial Sloan Kettering Cancer Center. His research program investigates the molecular mechanisms of oncogenic signaling, particularly through receptor tyrosine kinases (EGFR, ALK) and RAS GTPase pathways. A key recent discovery involves the role of membraneless cytoplasmic biomolecular condensates in driving oncogenic signaling and resistance. His work aims to understand tumor initiation, evolution, and therapeutic resistance to improve cancer therapy and patient outcomes. His recent publications highlight trends in cancer resistance mechanisms, tumor evolution, biomolecular condensates, and rational combination therapies. These works appear in high-impact journals such as Nature , Cancer Discovery , and Cell , reflecting a strong focus on translational and mechanistic cancer biology. Dr. Bivona has received significant recognition, including: NIH Director’s New Innovator Award Elected Member, American Society for Clinical Investigation He is actively involved in major research initiatives as Principal Investigator of the NIH/NCI U54 Bay Area Drug Resistance and Sensitivity Center and as a Chan-Zuckerberg Biohub Senior Investigator. His work includes advising on therapeutic strategies and securing substantial NIH funding for projects on RAS signaling, NF-κB inhibition, polytherapy optimization, and resistance mechanisms. Dr. Bivona leads the Bivona Lab at UCSF, a research team dedicated to understanding the molecular basis of cancer signaling and resistance, with a strong emphasis on translating findings into clinical applications for lung cancer patients.

Katharina HöferView profile

Professor

• Bacterial Epitranscriptomics
• RNA Modifications
• NAD-capped RNAs
• +4 more

Prof. Dr. Katharina Höfer is a Max Planck Research Group Leader at the Max Planck Institute for Terrestrial Microbiology in Marburg, Germany, where she heads the Research Group for Bacterial Epitranscriptomics. She is affiliated with SYNMIKRO, the Center for Synthetic Microbiology, a collaborative research center between the Max Planck Institute and Philipps-Universität Marburg. Her work bridges molecular biology, biochemistry, and microbiology to unravel the complex world of RNA modifications in bacteria. Dr. Höfer completed her academic journey with a Bachelor of Science from the University of Hannover in 2008, followed by a Master of Science in Molecular Biotechnology from Heidelberg University in 2011. She earned her Dr. rer. nat. from Heidelberg University's Institute of Pharmacy and Molecular Biotechnology in 2017, and continued as a Postdoctoral Researcher there until 2020. Dr. Höfer's research focuses on bacterial epitranscriptomics, particularly the study of NAD-capped RNAs in bacteria using Escherichia coli as a model organism. Her lab investigates how RNA modifications serve as epitranscriptomic mechanisms for gene regulation, exploring the connections between redox biology, gene expression, and regulation. By combining cell biological, biochemical, structural, chemical, and bioinformatic approaches, her team uncovers novel insights into RNA modifications and their functional implications in bacterial systems. Her recent work has expanded into bacteriophage research, examining the enigmatic epitranscriptome of phages and how viral infections alter host RNA modification landscapes. This interdisciplinary approach has positioned her at the forefront of understanding RNA-protein interactions, particularly through discoveries related to RNAylation - the conjugation of RNAs to proteins. The analysis of her recent publications reveals a strong focus on viral ADP-ribosyltransferases, phage engineering, and the functional consequences of RNA modifications during host-pathogen interactions. Dr. Höfer's scientific achievements have been recognized with several prestigious awards, including: ERC Starter Grant (2023) EMBO Young Investigator (2024) Otto Meyerhof Award from the German Society for Biochemistry & Molecular Biology (GBM) (2024) LOEWE Spitzenprofessur from Philipps-Universität Marburg (2024) As an advisor, Dr. Höfer has supervised numerous Master's and Bachelor's students, guiding research on topics ranging from phage infection mechanisms to RNA modifications and protein-RNA conjugation. Her group has received significant funding, most notably the ERC Starter Grant, which supports innovative research at the intersection of RNA biology and microbial systems. She maintains collaborative relationships with researchers across multiple institutions, as evidenced by her diverse publication record. The Höfer Lab, located at the Max Planck Institute for Terrestrial Microbiology, consists of a diverse team of doctoral researchers, technical assistants, guest scientists, and students. Current members include Elyés Gaaloul, Lydia Garrido Garcia-Dorado, Kitty Johnson, Helene Keuthen, Moritz Weber, Nurseda Yilmaz Demirel, Petra Mann (Technical Assistant), and several others. This collaborative environment fosters interdisciplinary research that combines molecular biology, biochemistry, and computational approaches to tackle fundamental questions in RNA biology.

Andrea BaccarelliView profile

Professor

• Environmental Health
• Air Pollution
• DNA Methylation
• +5 more

Andrea Baccarelli is the Dean of the Faculty and a Professor of Environmental Health at the Harvard T.H. Chan School of Public Health. His research focuses on the intersection of environmental exposures and human health, particularly examining how air pollution, metals, and climate factors influence aging, maternal-child outcomes, and chronic disease. His work involves extensive NIH-funded projects on topics including: Prenatal Traffic-Related Air Pollutants and Child Cognition Extracellular Vesicles in Aging Studies Epitranscriptomic Mechanisms of Arsenic-Induced Diabetes Maternal Obesity Risks from Particulate Pollution Key research areas include DNA Methylation , Environmental Epidemiology , and Extracellular Vesicle Biology . His recent publications highlight collaborations across 1120 concepts with 135 co-authors, including Joel Schwartz and Petros Koutrakis. He is actively involved in public health education initiatives, including the development of intensive short-term courses for health professionals.

Amanda GarnerView profile

Professor

• Medicinal Chemistry
• RNA Biology
• Cancer Therapeutics
• +3 more

Amanda Garner is a Professor in the Department of Medicinal Chemistry at the University of Michigan , focusing on RNA biology and cancer therapeutics. Her work centers on targeting RNA-binding proteins (RBPs) and translation regulation mechanisms, particularly eIF4E, which plays a critical role in oncogenic protein synthesis. Research Themes: eIF4E inhibition, RNA-protein interactions, mRNA cap analogs, and translational control in cancer. Collaborations: Active partnerships with researchers like Emilio L Cárdenas, Jeanne Stuckey, and Vibha Lama. Recent studies explore CRISPR-based screening for RNA-protein interactions, second-generation prodrugs for cancer therapy, and neuroprotective roles of αA-crystallin. She also contributes to diversity initiatives in medicinal chemistry through the ACS Division.

Kathy Fange LiuView profile

Associate Professor

• RNA Biochemistry
• Cancer Biology
• Epitranscriptomics
• +3 more

Kathy Fange Liu, Ph.D., is an Associate Professor with tenure at the University of Pennsylvania Perelman School of Medicine. She serves as Co-Director of the Penn Center for Genome Integrity and Group Lead at the Penn Institute for RNA Innovation. The lab combines deep mechanistic studies with innovative therapeutic development across four major research directions: X-Y paired homologous proteins, cancer fusion proteins, ribosome biology, and cross-RNA modification coregulation. Research highlights include pioneering the concept of RNA modification coregulation (DOI:10.1073/pnas.1913448117), where enzyme-mediated modifications across RNA species demonstrate interconnected networks. Current projects investigate rRNA-modifying enzymes' dual roles in ribosome assembly and genome organization, while developing targeted therapies for fusion oncoproteins like TRIM24-ERG (US patent 63/797,545). 2025 Damon Runyon-Rachleff Innovator Award Stage 2 2024 St. Baldrick's Research Grant 2023 Linda Pechenik Montague Investigator 2022 Damon Runyon & ACS Scholar awards 2019 NIH MIRA R35 award Lab members include 6 postdocs (Praneeth Bommisetti, Yanze Jian, Sarai Mendoza, Yulia Gonskikh, Hyojeong Hwang, Sheetal Tushir) and 3 graduate trainees. Former lab members Hui Shen (now professor at China Pharmaceutical University), Julian Stoute (Ph.D. 2023), and Jordan Ontiveros (Ph.D. 2022) received multiple fellowships during their tenure. Key grants include NIH/NHLBI R01 (2022), CZI Multi-Institutional Collaboration (2024), and continuous support from private foundations like CURE Childhood Cancer and Alex's Lemonade Stand. The lab actively develops technologies for RNA modification analysis while maintaining strong collaborative ties across Penn's epigenetics and structural biology programs.

• Bioinformatics
• Deep Learning
• Biosensors
• +5 more

Yang Zhang is a Professor at Tianjin University and has held academic positions at the Harbin Institute of Technology (2015-present) and The University of Tokyo (Visiting Professor, 2024). Education : PhD in Pathology from University of Cambridge (2012-2015) MPhil from University of Hong Kong (HKU-Pasteur Research Center, 2009-2011) His research bridges computational biology and experimental microbiology , focusing on: AI-powered microscopic imaging for disease diagnostics Deep learning analysis of multi-omics data (proteins, RNAs, etc.) Development of biosensors for pathogen and cancer detection Research Trends from 2018-2025: Consistent focus on deep learning applications Expanding from parasitology to broader cancer research Integration of electrochemical and optical biosensors Scientific Recognition : Elected Fellow of The Royal Society of Chemistry (2025) Elected Fellow of the Royal Society of Biology (2023) His work combines computational approaches (AI, protein language models) with experimental techniques (high-throughput sequencing, mass spectrometry) to address fundamental questions in disease mechanisms at the molecular level.

• Glycobiology
• Chemical Biology
• Glycosylation
• +5 more

Jennifer Kohler is an Associate Professor in the Department of Biochemistry at UT Southwestern Medical Center. She leads the Kohler Lab, which focuses on developing chemical biology tools to study glycosylation in biological systems. Her research has significant implications for understanding fundamental biology, cancer metastasis, and infectious diseases. Dr. Kohler completed her undergraduate degree in Chemistry at Bryn Mawr College. She earned her Ph.D. in the Chemistry Department at Yale University, where she studied the kinetics of protein-DNA interactions under Prof. Alanna Schepartz. From 2000-2004, she was an American Cancer Society postdoctoral fellow with Prof. Carolyn Bertozzi at the University of California, Berkeley. Dr. Kohler's research focuses on understanding the roles of glycoconjugates in biological systems. Her lab develops innovative chemical biology methods to address challenges in glycoscience, particularly through the creation of photocrosslinking sugar analogs that can be metabolically incorporated into cellular glycoconjugates. These tools enable the identification of transient glycan-mediated interactions that would otherwise be difficult to capture. Her work spans multiple areas including: Development of photocrosslinking reagents for sialic acid and GlcNAc Investigation of glycan-mediated host-pathogen interactions, particularly with cholera toxin Exploration of O-GlcNAc's role in nuclear transport Creation of methods to discover glycoprotein substrates of sialidases Understanding glycosylation in intestinal epithelial tissue Analysis of Dr. Kohler's recent publications (2021-2024) reveals a consistent focus on glycobiology with particular emphasis on sialic acid and O-GlcNAc modifications. Her work bridges chemical biology and disease mechanisms, with applications in infectious disease (particularly cholera), metabolism, and cancer. She frequently collaborates with other researchers worldwide and shares her innovative photocrosslinking reagents with the scientific community. Dr. Kohler was an American Cancer Society postdoctoral fellow during her time at UC Berkeley. While specific awards aren't detailed in the provided text, her sustained research program and numerous high-impact publications suggest recognition within her field. Dr. Kohler advises graduate students in the Biochemistry and Cell Regulation programs at UT Southwestern. Her research is supported by grants that enable her lab to develop and implement new tools for studying glycosylated molecules, with applications spanning fundamental biology, cancer metastasis, and infectious disease. She has mentored numerous students and postdoctoral fellows who have contributed to her extensive publication record. The Kohler Lab is dedicated to advancing glycoscience through innovative chemical biology approaches. The lab actively develops and shares photocrosslinking sugar analogs that have been adopted by research groups worldwide. Current research focuses on understanding glycosylation in intestinal epithelial tissue and its implications for host-pathogen interactions. The lab maintains strong collaborations with other research groups both within UT Southwestern and internationally.

Yuru WangView profile

Assistant Professor

• Epitranscriptomics
• RNA Modifications
• Pseudouridine
• +5 more

Yuru Wang is an Assistant Professor of Medicinal Chemistry at the University of Utah , College of Pharmacy. She is affiliated with both the Molecular Biology Program and the Biological Chemistry Program , where she leads the Wang Lab focused on epitranscriptomics and RNA therapeutics . Education: B.S., Nankai University Ph.D., University of California, Davis Research Interests: Dr. Wang's research centers on understanding RNA modifications such as pseudouridine and inosine , and their roles in cellular processes like immune responses, phase separation, and embryonic development. Her lab develops innovative molecular tools and therapeutic strategies targeting RNA modifications. Her work spans multiple disciplines including biochemistry , RNA biology , mass spectrometry , protein engineering , and genetics . Publications & Trends: Dr. Wang's recent publications (2023-2015) demonstrate a strong focus on pseudouridine detection and RNA modification mapping , particularly using advanced sequencing techniques like LEAD-m6A-seq and BID-seq . Her work also emphasizes enzyme engineering for RNA modification tools and ADAR enzyme specificity . Lab & Training: The Wang Lab provides an interdisciplinary training environment for graduate students and postdocs, preparing them for careers in RNA biology and therapeutics. The lab's ultimate goal is to develop innovative RNA-based therapies and identify new drug targets for human diseases.