
About
Amanda Garner is a Professor in the Department of Medicinal Chemistry at the University of Michigan, focusing on RNA biology and cancer therapeutics. Her work centers on targeting RNA-binding proteins (RBPs) and translation regulation mechanisms, particularly eIF4E, which plays a critical role in oncogenic protein synthesis.
- Research Themes: eIF4E inhibition, RNA-protein interactions, mRNA cap analogs, and translational control in cancer.
- Collaborations: Active partnerships with researchers like Emilio L Cárdenas, Jeanne Stuckey, and Vibha Lama.
Recent studies explore CRISPR-based screening for RNA-protein interactions, second-generation prodrugs for cancer therapy, and neuroprotective roles of αA-crystallin. She also contributes to diversity initiatives in medicinal chemistry through the ACS Division.
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