Find Academic Supervisors

Terence S. CroftsView profile

Assistant Professor

• Antibiotic resistome
• Microbiome
• Microbiology
• +3 more

Terence S. Crofts serves as an Assistant Professor at the University of Illinois Urbana-Champaign, leading the active Crofts Micro Lab research group. His work bridges microbiology, biochemistry, and clinical applications with a primary focus on antibiotic resistance mechanisms and host-microbiome interactions. Dr. Crofts' research centers on the antibiotic resistome across diverse environments including soil microbiomes, infant gut ecosystems, and human pathogens. His investigations span enzymatic resistance mechanisms (particularly nitroreductases and β-lactam catabolism), corrinoid biochemistry (vitamin B12 analogs), and the critical role of microbiome composition in neonatal sepsis outcomes and cancer immunotherapy efficacy. His lab employs genomic, biochemical, and gnotobiotic mouse model approaches to dissect microbial adaptation to antibiotics. Analysis of his 15 most recent publications (2014-2024) reveals three dominant research thrusts: (1) resistome dynamics in environmental and clinical settings, (2) microbiome-immune system crosstalk in disease models, and (3) specialized microbial metabolism of antibiotics and cofactors. His work increasingly connects fundamental resistance mechanisms to clinical outcomes, particularly in vulnerable populations like preterm infants. Dr. Crofts mentors a robust team of undergraduate and graduate researchers, as evidenced by lab group photos, award recognitions (including Elizabeth's SEBASM award), and student poster presentations. The Crofts Micro Lab maintains a collaborative environment with documented lab lunches, team activities, and active participation in scientific conferences. Lab members engage in techniques ranging from chemominipreps to metagenomic library construction, supporting the group's diverse research portfolio.

Đorđević MarkoView profile

Associate Professor

• Computational Biology
• Systems Biology
• Infectious Diseases
• +7 more

Marko Djordjevic is an Associate Professor at the Faculty of Biology, University of Belgrade. His research spans computational biology of infectious diseases, bacterial immune systems (CRISPR/Cas and restriction-modification systems), and quantitative understanding of infection progression with applications to SARS-CoV-2 and computational physics of quark-gluon plasma. Diploma in Physics, Faculty of Physics, University of Belgrade, Serbia. PhD in Biophysics and Bioinformatics, Department of Physics, Columbia University, USA. Postdoctoral training at the Mathematical Biosciences Institute, Ohio State University, USA. Djordjevic's research focuses on nonlinear regulatory dynamics of bacterial immune systems, their role in horizontal gene transfer, and modeling infection progression under social mitigation measures. His secondary interest in computational physics examines quark-gluon plasma dynamics via high-p⊥ observables and tomography. His recent publications address CRISPR/Cas regulation, restriction-modification systems, and SARS-CoV-2 transmissibility drivers. Grants from the Serbian Ministry of Science, Science Fund of Serbia, EU Marie Curie IRG, and Swiss National Science Foundation support his work.

Alexander MeeskeView profile

Assistant Professor

• CRISPR-Cas Systems
• Bacterial Immunity
• Bacteriophage Interactions
• +4 more

Alexander Meeske is an Assistant Professor at the University of Washington in the Department of Microbiology . His research focuses on the mechanistic relationships between CRISPR-Cas systems, bacterial hosts, and bacteriophages , utilizing high-throughput genetics, biochemical reconstitution, and microscopy. Established Listeria seeligeri as a model for RNA-targeting CRISPR-Cas13 immunity during postdoctoral work at Rockefeller University. Current work explores regulation of CRISPR immunity, phage resistance mechanisms, and non-immune roles of CRISPR systems. Research interests include: CRISPR-Cas Systems Anti-CRISPR Proteins Bacterial Cell Wall Synthesis Phage-Bacteria Coevolution RNA-Guided Immunity High-Throughput Genetic Screens Recent publications highlight discoveries in: CRISPR-Cas13 dormancy and resuscitation pathways (2019–2023). Anti-CRISPR protein mechanisms (2020, 2022). Phage-encoded escape strategies (2016, 2021). Cell wall synthesis in Bacillus subtilis (2013–2016). Lab members include: Postdocs: Shally Margolis, Shoshanna Kahne. PhD Students: Marshall Godsil, Sarina Kao, Amanda Antoch, Edith Sawyer, Luke Oriolt, Alison Ciling. Research Scientists: Maddie Williams, Mark Katz. Collaborations extend to the Guo Lab, focusing on joint PhD training programs.

Sarah FranklinView profile

Associate Professor

• Chromatin Remodeling
• Epigenetics
• Proteomics
• +3 more

Sarah Franklin is an Associate Professor of Cardiovascular Medicine at the University of Utah School of Medicine, where she leads research on epigenetic regulation of heart disease. She also serves as Assistant Director for the Rural & Underserved Utah Training Experience (RUUTE) program, mentoring students through summer research initiatives. Education: B.S. and Ph.D. in Molecular Biology from Brigham Young University Her research focuses on chromatin remodeling and histone modifications in cardiac hypertrophy and failure, utilizing proteomics, animal models, and biochemical approaches. Recent work explores SMYD1a's role in mitochondrial protection and translational applications for ischemic injury. The 15 most recent publications highlight her contributions to proteomic analysis of cardioprotective therapies (2025), genetic cardiomyopathy mechanisms (2023-2024), and foundational studies on chromatin structure in cardiac physiology (2011-2016). Key subfields include histone methylation, mitochondrial dynamics, and rural medical education.

• Biochemistry
• Molecular Biology
• Medicinal Chemistry
• +7 more

Enyedi Kata Nóra is a Lecturer at the Department of Organic Chemistry , Faculty of Science , ELTE Eötvös Loránd University , Budapest. Her research focuses on peptide-based drug conjugates, molecular targeting in cancer therapy, and structural studies of biologically active molecules. Role: Lecturer Email: kata.nora.enyedi@ttk.elte.hu Address: 1117 Budapest, Pázmány Péter sétány 1/a, Room 448 Research Interests: Enyedi's work spans Biochemistry , Molecular Biology , and Medicinal Chemistry , with a focus on: Design and synthesis of NGR and F3 peptide-drug conjugates Epigenetic regulation via histone variants (H2A.Z) Development of hydrogel systems for cancer cell viability Medical imaging techniques (PET/MRI) for tumor angiogenesis Structural studies of protein stability (Asn/Asp isomerization) Publication Trends: Recent studies emphasize targeted tumor therapy, radiolabeled peptides, 3D hydrogel models, and control peptide design. Key keywords include Drug Delivery , Molecular Imaging , and Peptide Synthesis .

Jill DowenView profile

Professor

• Gene Regulation
• Chromosome Structure
• Genome Organization
• +7 more

Jill Dowen is a Professor in the Department of Genetics at the University of North Carolina at Chapel Hill, focusing on the interplay between genome organization and gene expression. Her lab investigates how DNA looping influences cellular identity during development and disease, utilizing embryonic stem cells, cancer cells, and functional genomics approaches. Research interests include: Chromatin structure and transcriptional regulation 3D genome architecture in disease contexts Role of cohesin and Polycomb complexes in gene expression Histone modifications and their impact on chromatin dynamics Her recent publications highlight advancements in understanding cohesin's regulatory mechanisms, histone acetylation's role in MLL complex function, and Polycomb repressive complex interactions with lncRNA. The lab actively trains scientists and accepts applications for postdoctoral and graduate positions through the UNC BBSP PhD Program.

Thomas M VondriskaView profile

Professor

• Cardiovascular Epigenomics
• Chromatin Structure
• Heart Failure
• +4 more

Thomas M Vondriska is a Professor in the School of Medicine at the University of California Los Angeles, with joint appointments in the Departments of Anesthesiology, Medicine, and Physiology. His research focuses on understanding the epigenomic basis of heart disease, particularly how chromatin structure and regulation contribute to cardiac pathophysiology. Dr. Vondriska leads multiple NIH-funded research projects exploring novel therapeutic targets for heart failure and cardiac remodeling. Dr. Vondriska's research interests center on cardiovascular epigenomics, chromatin structure, and gene regulation in heart disease. His laboratory investigates how epigenetic modifications influence cardiac development, growth, and response to stress. Specific areas of focus include histone modifications, DNA methylation patterns, non-coding RNA regulation, and the three-dimensional organization of chromatin in cardiac cells. His work bridges basic molecular mechanisms with clinical applications in heart failure and cardiac hypertrophy. Analysis of Dr. Vondriska's recent publications reveals a strong emphasis on the intersection of epigenetics and cardiac physiology. His research demonstrates how chromatin architecture regulates cardiac gene expression during development and disease, with particular attention to heart failure with preserved ejection fraction (HFpEF), cardiac fibrosis, and arrhythmias. His work increasingly incorporates single-cell technologies, computational approaches, and translational studies connecting basic mechanisms to clinical applications. Dr. Vondriska has secured substantial NIH funding as Principal Investigator for multiple projects including "Epigenomic basis of resilience to heart failure" (R21HL150667), "Small molecule therapies targeting chromatin architecture in heart failure" (R01HL150225), and "Novel Mechanisms of LncRNA Mediated Epigenetic Regulation in Cardiac Hypertrophy" (R01HL143058). His research program has been continuously funded by NIH since 2006, reflecting the significance and productivity of his work in cardiovascular epigenomics. Dr. Vondriska leads a research laboratory focused on cardiac epigenomics and systems biology. His team employs advanced techniques including chromatin conformation capture, single-cell sequencing, proteomics, and computational modeling to investigate the molecular mechanisms underlying heart disease. The laboratory collaborates extensively with clinical researchers to translate basic findings into potential therapeutic approaches for cardiovascular conditions.

Simon A. JoosseView profile

Research Professor

• Oncology
• Cancer Genomics
• Liquid Biopsy
• +3 more

Simon A. Joosse is a Research Professor and Principal Investigator leading the Research Group in the Institute of Tumor Biology at the Center for Experimental Medicine, University Medical Center Hamburg-Eppendorf (UKE) under the University of Hamburg's Faculty of Medicine. His work focuses on liquid biopsy technologies, circulating tumor cells (CTCs), and genomic profiling in cancer diagnostics and therapy monitoring. He is actively involved in the European Liquid Biopsy Society (ELBS), advancing precision oncology through biomarker discovery and clinical applications. Dr. Joosse's research emphasizes the development of non-invasive tools for early cancer detection, treatment resistance analysis, and molecular characterization of metastatic progression. His studies span multiple cancer types, including ovarian, breast, prostate, and head-and-neck cancers, with a particular emphasis on epigenetic modifications (e.g., BRCA1 promoter methylation) and genomic instability. Key contributions include identifying CTC-based biomarkers and optimizing nanopore sequencing for clinical use. His publications highlight advancements in CTC capture technologies, ctDNA analysis, and immune profiling in metastatic disease. Collaborations involve interdisciplinary teams in oncology, immunology, and clinical translation. Dr. Joosse's work bridges basic science and clinical practice, aiming to improve patient outcomes through personalized medicine.

Stephen RamseyView profile

Associate Professor

• Computational Systems Biology
• Bioinformatics
• Precision Medicine
• +6 more

Stephen Ramsey, an Associate Professor at Oregon State University, holds dual appointments in the School of Electrical Engineering and Computer Science (College of Engineering) and the Department of Biomedical Sciences (Carlson College of Veterinary Medicine). With a PhD in Physics from the University of Maryland, his postdoctoral training in computational genomics at the University of Washington, and professional experience at the Institute for Systems Biology and Center for Infectious Disease Research, Ramsey bridges computational methods with biomedical applications. Education : Ph.D., Physics, University of Maryland; M.S., Physics, University of Maryland; Sc.B., Mathematical Physics, Brown University Ramsey specializes in computational systems biology , focusing on bioinformatics , biomedical knowledge graphs , and precision medicine . His research integrates machine learning , gene regulatory network modeling , and multi-omics data analysis to address challenges in rare disease diagnostics , drug monitoring , and inflammatory disease mechanisms . Current work includes AI-driven biomedical translation and electrochemical biosensor development for non-invasive diagnostics . Recent publications highlight knowledge graph applications in translational biomedicine , causal network inference in clinical-environmental data integration , and cross-species cancer transcriptomics . His team develops tools like RTX-KG2 and PloverDB to standardize biomedical data sharing and semantic reasoning . Scientific Awards : 2019 Zoetis Award (Carlson College of Veterinary Medicine) 2016 NSF CAREER Award 2016 PhRMA New Investigator Award 2010 NIH K25 Mentored Quantitative Research Award Ramsey advises in computational biology courses (CS 446/546) and contributes to biomedical AI through projects like mediKanren for rare disease diagnostics . His NSF-funded research explores gene expression noise and regulatory network dynamics , while NIH and PhRMA grants support his translational medicine initiatives. He leads the Ramsey Laboratory , which develops graph-based reasoning tools for biomedical data translation and multi-omics integration . The lab's work spans comparative oncology models, electrochemical biosensors , and knowledge graph infrastructure for clinical decision support .

• Cancer Genomics
• Pan-Cancer Analysis
• Neuro-Immunology of Cancer
• +5 more

Dr. Ida Deichaite is an Assistant Adjunct Professor in the Department of Radiation Medicine and Applied Sciences at the University of California, San Diego. With a background in virology and molecular biology, she applies genomics analysis to identify susceptibility targets for aggressive cancers using a bed-to-bench approach that integrates real-world genomics with clinical data. Prior to her faculty appointment in November 2019, she collaborated with UCSD Moores Cancer Center leadership, private sector partners, and grant agencies to develop translational programs that resulted in FDA-approved therapeutics. Education B.Sc. in Horticulture, Hebrew University, Jerusalem (1983) M.Sc. in Virology, Weizmann Institute (1985, Cum Laude) Ph.D. in Molecular Biology, Princeton University (1991) Postdoctoral Training in Molecular Biology, Memorial Sloan Kettering Cancer Center (1993) Research Focus Dr. Deichaite's research program focuses on identifying actionable targets and mechanisms for oncology diagnostics and therapeutics. Her work spans cancer genomics, pan-cancer analyses, neuro-immunology of cancer, and translational oncology, with particular expertise in head and neck cancers, prostate cancer, and radiogenomics. She employs genomic analysis to overcome limitations of experimental models and accelerate clinical translation. Publication Focus Her recent publications demonstrate a strong focus on cancer biomarkers, immunotherapy response prediction, radiation toxicity mechanisms, and immune evasion in prostate cancer. Earlier work established foundations in molecular virology and protein biochemistry, while current research emphasizes clinical applications of genomics in oncology. Awards and Honors 1st Prize - Best Poster Presentation, International Cancer Education Conference (2018) Employee of the Year, UC San Diego (2014) Fellowship Award, Princeton University (1986) M.Sc. Cum Laude, Weizmann Institute (1985) Professional Contributions Dr. Deichaite contributed to the development of FDA-approved therapeutics including Daurismo (glasdegib) and INREBIC (fedratinib), and participated in high-value acquisitions such as VelosBio's acquisition by Merck. She maintains active collaborations across institutions and industry partners to advance translational oncology programs.

• RNA Biology
• Neurodegenerative Diseases
• Neuronal mRNA Translation
• +5 more

Junjie Guo is an Associate Professor of Neuroscience at Yale School of Medicine, leading the Guo Lab focused on RNA biology and neurological mechanisms. He holds affiliations with the Interdepartmental Neuroscience Program, Center for RNA Science and Medicine, and Wu Tsai Institute. Education : B.A. in Biology (Peking University, 2006), Ph.D. in Neuroscience (Johns Hopkins University, 2011), Postdoctoral Fellow at Whitehead Institute/MIT (2017). Research Interests : Investigates RNA dysregulation in neurodegenerative diseases (e.g., ALS/FTD), noncanonical mRNA translation in neuronal development, and spatial/temporal regulation of neuronal mRNA transport and local translation. Utilizes genomic, molecular, and computational approaches in stem cells, neuronal models, and mouse models. Recent Article Trends : Focuses on SARS-CoV-2 replication mechanisms, RNA structural biology (e.g., G-quadruplexes and tandem repeats), and translational control pathways. Highlights include CRISPR-based screens for viral dependency factors and discovery of alternative translation initiation roles in synaptic organizers. Awards : McKnight Neurobiology of Brain Disorders Award (2023), NYSCF-Robertson Neuroscience Investigator (2021), NIH New Innovator Award (2018), and multiple fellowships from the Klingenstein-Simons and Damon Runyon Foundations. Advising & Grants : Mentors postdocs (e.g., Zhen Lei), graduate students (e.g., Ata Isiktas), and others. Leads NIH-funded projects on RNA biology and neurological disorders. Collaborates with researchers like Marina Picciotto and Craig Wilen. Labs/Teams : Directs the Guo Lab, part of the Yale Neuroscience community. Engages in interdisciplinary initiatives through the Wu Tsai Institute and Center for RNA Science and Medicine.

David KlenermanView profile

Professor

• Protein folding and misfolding
• Molecular basis of neurodegenerative disease
• Single molecule fluorescence
• +4 more

David Klenerman is a Professor of Molecular Medicine at the University of Cambridge, holding the Royal Society Chair since 2016. Previously, he was Professor of Biophysical Chemistry (2007–2016), Reader in Biophysical Chemistry (2004–2007), and Lecturer in the Department of Chemistry (1994–2004). His research focuses on biophysical methods applied to biomedical problems, including protein misfolding, neurodegenerative diseases, and high-speed DNA sequencing. He co-invented the Solexa (Illumina) sequencing technology and founded the biotech company Solexa. Research Interests: Protein folding/misfolding mechanisms Molecular basis of neurodegenerative diseases (Parkinson's, Alzheimer's) Single-molecule fluorescence microscopy Imaging adaptive immune responses Genomic technologies (DNA sequencing) Key Awards: 2022 Breakthrough Prize in Life Sciences 2021 Millennium Technology Prize 2018 Royal Medal (Royal Society) 2016 Royal Society Glaxo Wellcome Professorship 2012 Fellowship of the Royal Society Labs/Teams: Co-founder of Solexa (now Illumina), leading interdisciplinary research groups focused on biophysical techniques for biomedical applications. His work bridges chemistry, physics, and medicine, with applications in diagnostics and drug discovery.

Cedar HowardView profile

Professor

• Biochemistry
• Molecular Biology
• DNA Methylation
• +3 more

Prof. Cedar Howard is a distinguished Professor of Molecular Biology at the Hebrew University Medical School. His career spans decades of groundbreaking research in DNA methylation, gene regulation, and epigenetics, with significant contributions to understanding chromatin structure and transcriptional repression. Research Focus: His work primarily explores DNA methylation mechanisms Epigenetic gene silencing Chromatin dynamics CpG island regulation Transcriptional control Cancer epigenetics Scientific Contributions: His research on methylation patterns in higher organisms, transcriptional repression, and Polycomb-mediated epigenetic marks has shaped modern molecular biology. Notable publications include studies on DNA methylation inheritance, chromatin accessibility, and cancer-related methylation changes. Awards & Honors: Wolf Prize in Medicine (2008) Israel Prize in Biology (1999) Gairdner International Award (2011) Emet Prize in Medicine (2009) Member, Israel Academy of Sciences (2003)

M. Reza GhadiriView profile

Professor

• Organic Chemistry
• Bioorganic Chemistry
• Materials Chemistry
• +7 more

M. Reza Ghadiri, PhD, is a Professor in the Departments of Chemistry and Molecular Biology at The Scripps Research Institute (TSRI), holding the Darlene V. Shiley Chair in Chemistry. His research spans organic, bioorganic, and materials chemistry, with a focus on interdisciplinary approaches to biomaterial design, systems chemistry, and the origins of life. Ghadiri leads the Ghadiri Lab, which investigates peptide self-assembly, synthetic biology, and drug development, particularly in HDL modulation and histone deacetylase inhibitors. Education: B.A. in Chemistry (University of Wisconsin-Milwaukee, 1982); Ph.D. in Chemistry (University of Wisconsin-Madison, 1987). Research interests include peptide architecture, biosensor arrays, self-replicating molecular systems, and applications in medicine and nanotechnology. Notable achievements include pioneering work on peptide-based nanotubes and enzymatic replication systems. His lab currently explores gut microbiome modulation for chronic disease intervention. Awards include the Feynman Prize in Nanotechnology (1998), Arthur C. Cope Scholar Award (1999), and the Ronald Breslow Award (2022). The lab collaborates on projects such as DNA-programmed enzymes and next-generation nanopore sequencing.

• Biosensors
• Photonic Devices
• Biomedical Engineering
• +4 more

Dr Tracy Melvin is an Associate Professor at the University of Southampton, specializing in interdisciplinary research at the intersection of photonics, biomedical engineering, and molecular biology. Her work focuses on developing advanced photonic devices and nanotechnologies for biological sensing, particularly in DNA analysis and skin conductivity studies. Research interests include biosensors, microfluidics, and molecular diffusion Active collaborations with the Institute for Life Sciences Key funding from Biotechnology & Biological Sciences Research Council (BBSRC) Her recent publications highlight innovations in nanoporous gold membranes, silica nanowires for UV sensing, and microfluidic systems for single-molecule DNA stretching. These works emphasize applications in medical diagnostics, genetic analysis, and biophotonic detection. Tracy Melvin currently supervises PhD student Charlotte Law and has held external advisory roles with prestigious organizations including the BBSRC Engineering and Biological Sciences Panel (2006-2009) and EU Marie Curie Fellowships LIFE Fellowship Review Panel (2011).