
M. Reza Ghadiri
Professor · Organic Chemistry
Irell and Manella Graduate School of Biological SciencesAbout
M. Reza Ghadiri, PhD, is a Professor in the Departments of Chemistry and Molecular Biology at The Scripps Research Institute (TSRI), holding the Darlene V. Shiley Chair in Chemistry. His research spans organic, bioorganic, and materials chemistry, with a focus on interdisciplinary approaches to biomaterial design, systems chemistry, and the origins of life. Ghadiri leads the Ghadiri Lab, which investigates peptide self-assembly, synthetic biology, and drug development, particularly in HDL modulation and histone deacetylase inhibitors.
Education: B.A. in Chemistry (University of Wisconsin-Milwaukee, 1982); Ph.D. in Chemistry (University of Wisconsin-Madison, 1987).
Research interests include peptide architecture, biosensor arrays, self-replicating molecular systems, and applications in medicine and nanotechnology. Notable achievements include pioneering work on peptide-based nanotubes and enzymatic replication systems. His lab currently explores gut microbiome modulation for chronic disease intervention.
Awards include the Feynman Prize in Nanotechnology (1998), Arthur C. Cope Scholar Award (1999), and the Ronald Breslow Award (2022). The lab collaborates on projects such as DNA-programmed enzymes and next-generation nanopore sequencing.
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