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Sourav BanerjeeView profile

Senior Lecturer

• Cancer Biology
• Neuro-Oncology
• Molecular Pharmacology
• +3 more

Dr. Sourav Banerjee is a Senior Lecturer in Cancer Research at the University of Dundee's School of Medicine, Department of Cancer Research. He holds a Master's degree from the University of Glasgow and a PhD from the MRC Protein Phosphorylation and Ubiquitylation Unit at the University of Dundee. His research focuses on understanding the role of extracellular post-translational modifications, particularly phosphorylation, in glioblastoma progression and identifying novel biomarkers for diagnosis and treatment. Banerjee's work integrates molecular biology, drug discovery, and translational medicine to develop therapies targeting aggressive cancers like glioblastoma and triple-negative breast cancer. Education: Masters in Life Sciences, University of Glasgow (2009) PhD in Life Sciences, University of Dundee (2013) His current research emphasizes the oncogenic roles of extracellular phosphorylations in glioblastoma, leveraging interdisciplinary approaches to design kinase inhibitors and biomarkers. Recent projects include developing brain-penetrant small molecules and studying DYRK2's role in proteasome regulation. Banerjee has secured significant grants, including a £150k Rosetrees Trust Translational Award (2025) and a UKRI Future Leaders Fellowship (2022). Key Awards: UKRI Future Leaders Fellowship (2022) Rosetrees Trust Translational Award (2025) Emerging Leaders Award (2023) Student-led Award for Innovative and Inspirational Teaching (2024) His lab collaborates on projects such as the CNSLive brain tumor program and explores synthetic lethality in glioma. Banerjee actively engages in public outreach, presenting on cancer research and drug development.

• Virology
• Cell Biology
• Molecular Biology
• +4 more

Kashif Mehmood is a Research Fellow in the Genetics Department at Yale School of Medicine, Yale University. His research focuses on virology, cell biology, and molecular mechanisms of viral entry and host-pathogen interactions. He investigates JC polyomavirus entry dynamics mediated by serotonin receptors, influenza hemagglutinin interactions with membrane lipids, and retromer-mediated transport pathways. Additionally, he explores microbial production of keratinase for sustainable waste management. His work bridges virology, neuroscience, and biotechnology, with implications for understanding viral pathogenesis and developing eco-friendly enzymatic solutions. Research interests include viral trafficking mechanisms, receptor-ligand interactions, lipid signaling, and industrial enzyme applications. Notable contributions address JC polyomavirus entry via serotonin receptors, influenza virus membrane fusion dynamics, and Bacillus velezensis-derived keratinase for keratin waste degradation.

• Neuroscience
• Molecular Biology
• Autism Spectrum Disorder
• +3 more

Wooyoung Eric Jang is a Researcher in the Department of Neurology at Yale School of Medicine. His research focuses on molecular mechanisms of autism spectrum disorder (ASD), particularly through Wnt/β-catenin signaling pathways and Cntnap2-dependent networks. He uses multi-omics analysis and mouse models to study neurodevelopmental disorders. Education: PhD in Chemistry, KyungHee University BS in Chemistry, University of California, Irvine Research Interests: Genetic and cellular pathways in ASD, dysregulation of signaling networks, integrative omics approaches, and translational research for neurodevelopmental disorders. Labs: Srikant Rangaraju Laboratory (300 George Street, New Haven, CT).

• Hepatobiliary Surgery
• Cancer Therapy
• Magnetic Surgery
• +4 more

Lyu Yi is a distinguished academic and clinician serving as Professor in the Department of Hepatobiliary Surgery at Xi'an Jiaotong University. He currently holds leadership roles including Vice President of Xi'an Jiaotong University, Director of The First Affiliated Hospital, and Director of the National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine. His career spans over three decades in hepatobiliary surgery, transplantation medicine, and biomedical innovation. Education: Bachelor's in Clinical Medicine (1984, Xi'an Medical College) Master's (1990) and PhD (1995) in General Surgery from Xi'an Medical College Postdoctoral training in Surgery at Nippon Medical School Hospital, Tokyo (1998–2000) Research focuses on magnetic surgery innovations, liver transplantation, cancer therapy, and regenerative medicine. Key contributions include magnetic anastomosis devices and consensus guidelines for magnetic surgical techniques. Awards include the First Prize of Chinese Medical Technology Award (2018) and National Teaching Achievement Award (2023). Editor-in-Chief of Magnetic Medicine and holds leadership roles in surgical societies like the American College of Surgeons. Grants include National Key Research Programs (e.g., 2023YFF0713700, ¥120M) and NSFC projects. Over 30 patents filed, including magnetic vascular anastomosis systems. Active in surgical education and training device development such as the 'Magnetic Spiderman' surgical simulator.

• Developmental neurobiology
• axon guidance
• neural plasticity
• +3 more

Associate Professor Catherine Leamey is a Senior Lecturer in Physiology within the School of Medical Sciences at the University of Sydney, affiliated with the Bosch Institute. Her research focuses on developmental neurobiology with particular emphasis on axon guidance and neural plasticity mechanisms in the visual system. Dr. Leamey's research interests center on understanding how neural circuits develop and function, with a specific focus on the role of teneurin proteins (particularly Ten-m3) in visual system development. Her work employs animal models , cellular/molecular approaches , and growth & development methodologies to investigate how environmental factors influence neural development. Her research spans behavioral neuroscience , the nervous system , neurosciences , vision , and axon guidance mechanisms. Analysis of her recent publications (2014-2025) reveals a consistent research trajectory focused on teneurin proteins and their role in neural circuit formation, particularly in the visual system. Her work has increasingly incorporated microglial function in neuroplasticity and has expanded into optogenetic approaches for vision restoration. The research demonstrates sophisticated integration of molecular biology, developmental neuroscience, and behavioral analysis, with significant implications for understanding neural development disorders. Dr. Leamey has successfully supervised multiple PhD students, including Hannan Mansuri who is researching 'Retinal Ganglion Cells in Binocular Vision and the effects of Teneurin proteins.' She has secured substantial research funding from major organizations including the National Health and Medical Research Council (NHMRC), Australian Research Council (ARC), Simons Foundation, and the Michael J. Fox Foundation for Parkinson's Research. Her grants span diverse areas including visual system development, neural circuit mapping, and optogenetic vision restoration. Her laboratory appears to focus on neural development using mouse models, with particular expertise in visual system circuitry, teneurin protein function, and the impact of environmental enrichment on neural development. The research group combines molecular, cellular, and behavioral approaches to investigate fundamental mechanisms of neural circuit formation and plasticity.

• Molecular Biology
• Genetic Biology
• Invertebrate Neurobiology
• +3 more

Dr. Fernando Calahorro Nunez is a Research Fellow at the University of Southampton, specializing in molecular and genetic biology with a focus on cellular circuits and atypical behaviors. He utilizes Caenorhabditis elegans as a model organism to study gene functions in complex behaviors, particularly in the context of drug discovery for neurodevelopmental disorders and parasitic nematode biology. His work bridges fundamental research with applied studies, collaborating with agrochemical industries to develop novel antiparasitic compounds. His research interests span molecular neurobiology, invertebrate behavior, and drug discovery, with notable contributions to understanding neuroligin-dependent social behaviors and cholinergic signaling pathways. Current projects include investigating autism-associated genes and developing microfluidic assays for drug screening in neurobehavioral disorders. Dr. Calahorro’s expertise in parasitic nematode neurobiology has positioned him to explore host plant invasion mechanisms and test compound libraries for antiparasitic effects. His interdisciplinary approach integrates genetic, pharmacological, and behavioral analyses to address both basic and translational research questions.

• Neuroscience
• Stem Cell Therapy
• Parkinson's Disease
• +3 more

Professor Lachlan Thompson is a leading academic in neurogenesis and neural transplantation, affiliated with the School of Medical Sciences. His work focuses on advancing stem cell therapies for neurodegenerative diseases like Parkinson’s, particularly through engineered neural grafts and hydrogel-based delivery systems. He leads research on optimizing stem cell differentiation, immune evasion, and functional integration within host neural circuits. Current research students include Laura Ancellotti and Alex Johnson. Key grants include a 2024 NHMRC Ideas Grant for improving Parkinson’s cell therapies and 2023 startup funding for establishing his research programs. His lab collaborates with the Charles Perkins Centre, focusing on translational neuroregenerative strategies. Research interests span stem cell engineering, neural circuit reconstruction, and disease modeling using patient-derived iPSCs. Recent work emphasizes hydrogel oxygen reservoirs, suicide gene activation in grafts, and developmental timing of neural progenitors. Over 80 publications detail advancements in neural transplantation safety, gene therapy approaches, and rodent models of neurological disorders. Awards and recognitions are not explicitly mentioned, though his high-impact publications and NHMRC grants highlight his academic standing. His lab integrates biomaterials science, genetic engineering, and clinical translation to address unmet needs in neurodegenerative therapies.

David C. ChanView profile

Professor

• Mitochondrial Dynamics
• Biological Engineering
• Cellular Biology
• +7 more

David C. Chan is the Harold and Violet Alvarez Professor of Biology and Dean of Graduate Studies at the California Institute of Technology (Caltech). He holds a dual M.D./Ph.D. from Harvard Medical School and an A.B. from Harvard College. His research focuses on mitochondrial dynamics, exploring their molecular mechanisms, physiological roles, and implications in diseases such as Charcot-Marie-Tooth disease and mitochondrial encephalomyopathies. Education: A.B., Harvard College, 1988 M.D. and Ph.D., Harvard Medical School, 1996 Research Interests: Dr. Chan’s lab investigates mitochondrial fusion/fission, mitophagy, and their roles in cellular function. Key areas include: Mitochondrial membrane fusion mechanisms (e.g., mitofusins, OPA1) Fission regulation via Drp1 and receptors like MFF Pathological consequences of mitochondrial dysfunction in neurodegenerative and metabolic disorders Publications: Recent work highlights studies on lipid profiles in mitochondrial-deficient cells, mitophagy’s role in ferroptosis resistance, and OPA1’s structural role in cristae remodeling. These findings underscore mitochondrial dynamics as central to cellular health and disease progression. Awards: Howard Hughes Medical Institute (HHMI) Investigator (2008–2014) Lab & Collaborations: His group employs genetics, biochemistry, and structural biology to dissect mitochondrial processes. Ongoing projects include modeling mitochondrial diseases (e.g., CMT2A) and exploring therapeutic targets for mitochondrial dysfunction.

• Membrane Biology
• Protein Folding
• Biophysics
• +6 more

Yongli Zhang is a Professor of Cell Biology and holds a secondary appointment as an Associate Professor in Molecular Biophysics and Biochemistry at Yale University. His research focuses on molecular mechanisms of membrane fusion, protein folding dynamics, and the development of single-molecule biophysical tools. He earned a bachelor’s degree in applied physics from China, a master’s in theoretical physics from the Chinese Academy of Sciences, and a PhD in Molecular Biophysics and Biochemistry from Yale University. His postdoctoral training at UC Berkeley under Prof. Carlos Bustamante expanded his expertise in optical tweezers and molecular biophysics. Key areas of research include regulated SNARE protein assembly, membrane protein interactions, and instrumentation development. The Zhang Lab uses advanced optical tweezers and fluorescence microscopy to study molecular forces in biological processes like exocytosis and endocytosis. Recent work explores SNARE-mediated membrane fusion mechanisms and the role of mechanical forces in protein function. Awards include the Jane Coffin Childs Postdoctoral Fellowship and the Sinsheimer Scholar award. The lab is actively involved in training students and postdocs in biophysical techniques and interdisciplinary research. Collaborations span structural biology, neuroscience, and computational modeling to address fundamental questions in membrane biology and protein dynamics.

• Biophysics
• Neuroscience
• Mechanotransduction
• +4 more

Slav Bagriantsev is a Professor in the Department of Cellular & Molecular Physiology at Yale School of Medicine. His research focuses on mechanotransduction, sensory receptor biology, and physiological adaptations in hibernation. Bagriantsev holds a PhD from the University of Illinois at Chicago and completed postdoctoral training at the University of California, San Francisco (2012). He leads the Slav Lab, investigating touch sensation mechanisms and hibernation physiology in animals like ground squirrels. Research Interests: His work explores how mechanosensitive ion channels mediate touch detection in specialized sensory organs (e.g., Pacinian corpuscles), and how hibernating mammals survive extreme conditions without water or food. Key projects include studying neural adaptations enabling months-long torpor states and identifying molecular mechanisms underlying cold tolerance. Publications Trends: Recent work emphasizes structural biology of touch receptors and neuroendocrine regulation during hibernation. Notable findings include the discovery of how ground squirrels suppress thirst mechanisms and the role of hypothalamic hormones in physiological anorexia during torpor. Awards: National Science Foundation CAREER Award (2015) American Heart Association Scientist Development Grant (2014) Genentech Foundation Postdoctoral Fellowship (2009) Advising & Lab: The Slav Lab collaborates with researchers like Elena Gracheva and Yury Nikolaev, focusing on interdisciplinary projects combining electrophysiology, structural biology, and animal behavior. Current efforts aim to translate hibernation biology insights into human medical applications like organ preservation and metabolic therapy.

• Cell Biology
• Epithelial Cell Physiology
• Membrane Protein Trafficking
• +5 more

Michael J. Caplan is the C.N.H. Long Professor of Cellular and Molecular Physiology and Professor of Cell Biology at Yale School of Medicine, where he also serves as Chair of the Department of Cellular and Molecular Physiology. He has been a faculty member at Yale since 1988, following the completion of his M.D. and Ph.D. degrees from Yale University in 1987. His academic journey began with a bachelor's degree in Biology from Harvard University in 1980. Dr. Caplan's research program focuses on understanding how membrane proteins are sorted in polarized epithelial cells, with particular emphasis on the Na,K-ATPase (sodium pump) in renal epithelial cells. His laboratory has made significant contributions to understanding the mechanisms responsible for Autosomal Dominant Polycystic Kidney Disease (ADPKD), particularly through studies of the polycystin-1 and polycystin-2 proteins. His work has revealed that polycystin-1 undergoes proteolytic cleavage to release its C-terminal tail, which enters the nucleus and modulates signaling pathways including Wnt signaling. His research also explores connections between renal cilia and olfactory signaling pathways in kidney function. Analysis of Dr. Caplan's recent publications reveals a strong focus on the molecular mechanisms underlying polycystic kidney disease, with particular attention to protein trafficking, membrane contact sites, transcriptional regulation in cystic cells, and novel therapeutic approaches. His work spans multiple disciplines including cell biology, molecular physiology, and translational medicine, with increasing integration of advanced imaging techniques and nanotechnology approaches. Dr. Caplan has received numerous prestigious awards including: Fellow of the American Association for the Advancement of Science (2023) Carl W. Gottschalk Distinguished Lectureship from the American Physiological Society (2012) Young Investigator Award from the American Society of Nephrology (1998) National Young Investigator Award from the National Science Foundation Fellowships from the Helen Hay Whitney Foundation and David and Lucille Packard Foundation As an educator and mentor, Dr. Caplan has received Yale's Postdoctoral Mentoring Prize (2010) and Bohmfalk Award for Excellence in Basic Science Teaching (2000). He currently serves as Editor-in-Chief of the journal Physiology and on the Board of Directors of the American Physiological Society. His laboratory continues to be at the forefront of research on kidney cell biology and polycystic kidney disease pathogenesis, with ongoing investigations into novel therapeutic targets and mechanisms of disease progression.

Min ChenView profile

Professor

• Statistical Genomics
• Bioinformatics
• Bayesian Methods
• +5 more

Dr. Min Chen is a Professor in the Department of Mathematical Sciences at the University of Texas at Dallas (UTD), affiliated with the School of Natural Sciences and Mathematics. He holds an adjunct professorship at the University of Texas Southwestern Medical Center. His expertise spans statistical genomics, bioinformatics, Bayesian methods, and sampling techniques. He completed his Ph.D. in Statistics and Decision Science at the University of Texas at Austin and a postdoctoral fellowship in statistical genomics at Yale University. Education: B.S. in Computer Science (University of Science & Technology of China, 1994); M.A. in Statistics (University of Pittsburgh, 1999); Ph.D. in Statistics (UT Austin, 2006); Postdoc in Statistical Genomics (Yale University, 2008–2010). Research focuses on statistical methodologies in genomics, including genome-wide association studies, network-based modeling, and Bayesian integrative analysis. He also explores spatial modeling and ranked set sampling. His work addresses challenges in cancer genetics, epigenetics, and single-cell gene regulation. Notable awards include the NIH Career Development Award (2013), David Bruton Fellowship (2006), and R.L. Anderson Student Paper Award (2006). He is a member of the American Statistical Association and International Chinese Statistical Association. He advises graduate students in Data Science, Statistics, and Bioinformatics & Computational Biology (BCBM) programs. His teaching includes courses on advanced statistical methods and data science. Research contributions span over 40 peer-reviewed articles, with recent work in tumor pathology imaging, antibiotic resistance, and Alzheimer’s disease mechanisms.

Emmanuel PothosView profile

Associate Professor

• Neuroscience
• Neurochemistry
• Molecular Biology
• +7 more

Emmanuel Pothos is an Associate Professor at Tufts University School of Medicine in the Department of Immunology. His research explores the cellular and molecular mechanisms of synaptic neurotransmission in the midbrain and its catecholaminergic projections, with a focus on neurochemistry and molecular biology of disorders like obesity, drug addiction, psychotic disorders, and Parkinson’s disease. He leads a lab studying the plasticity of CNS catecholamine quantal size and its pharmacological intervention potential. Doctor of Philosophy, Princeton University, 1994 Master of Arts, Princeton University, 1990 Bachelor of Arts, University of Athens, 1988 His publications span neuroscience, neuroendocrinology, and translational medicine, addressing topics such as insulin signaling in astrocytes, dopamine turnover in obesity, and genetic models of dyskinesia. He has secured significant grants from NIH, Pfizer, and other foundations to investigate preclinical interventions for obesity, addiction, and neurodegenerative diseases. Astrocyte-derived signals and mental illness (NIH, 2021–2026) Intranasal delivery of GDNF for opioid relapse prevention (CTSI, 2020–2022) MCH antibody therapy for IBD (Pfizer, 2018–2019) He teaches courses in Addiction Medicine, Translational Pharmacology, and Graduate Research at Tufts, and has presented at conferences including the Society for Neuroscience Annual Meeting and Tufts Talks Obesity Seminar Series. His work bridges neurobiology, metabolic disorders, and public health policy.

• Bone Metabolism
• Kidney Disease
• Transcriptional Regulation
• +5 more

Jackie A. Fretz, PhD, is a Researcher at Yale University's Yale School of Medicine, affiliated with the Department of Orthopaedics & Rehabilitation. She manages the Histology and Histomorphometry Laboratory and holds a PhD from the University of Wisconsin-Madison. Her research focuses on the transcription factor EBF1's role in cellular fate determination, particularly in bone, kidney, and adipocyte biology. She investigates how EBF1 regulates mesenchymal progenitors, marrow adipogenesis, and kidney glomerular development. Education: PhD in Biochemistry (University of Wisconsin-Madison, 2007); BS in Biochemistry and Molecular Biology (University of New Hampshire, 2002). Postdoctoral training at Yale School of Medicine (2011). Research interests include EBF1's actions in bone vasculature, renal pathophysiology, and metabolic pathways. Her work bridges bone and kidney diseases, revealing conserved mechanisms in mesenchymal cell regulation. Recent studies explore EBF1's role in fracture repair, chronic kidney disease-mineral bone disorders, and FGF23 regulation. Awards include the ASBMR Mid-Career Travel Grant (2022) and the American Society of Bone and Mineral Research President's Poster Award (2011). She has presented at international conferences such as the ASBMR Annual Meeting and the NIH Workshop on FGF-23. Laboratory: Orthopaedic Histology and Histomorphometry Laboratory, focused on histological techniques and skeletal research. Active in methodological advancements like methyl methacrylate embedding for bone analysis.

• Structural Biology
• Bacterial Enzymology
• Neuroscience
• +3 more

Sudhanshu Gautam is a Research Fellow at the Department of Cell Biology , Yale School of Medicine , focusing on molecular mechanisms of cellular processes. His work bridges structural biology, bacterial enzymology, and neuroscience. Education: PhD, Indian Institute of Science (2022), Molecular Biophysics Unit Integrated BSc-MSc, National Institute of Science Education and Research (2015) Research Interests include structural analysis of proteins involved in synaptic vesicle exocytosis, bacterial DNA repair enzymes, and transcriptional regulation. His expertise spans: Cryo-electron tomography and tethered giant unilamellar vesicles Mycobacterial cyclic-di-AMP homeostasis RNA polymerase functional dynamics Phosphatidate phosphatase roles in cellular respiration Publication Trends highlight investigations into: Cyclic Di-AMP synthase/hydrolase systems in Mycobacterium smegmatis Antibiotic discovery targeting RNA polymerase Protein structure-function relationships across bacterial and eukaryotic systems Lipid metabolism in Tetrahymena and yeast Laboratory Affiliation: Rothman Lab, Yale School of Medicine, specializing in cellular and molecular neuroscience research.