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Xiangchun XuanView profile

Professor

• Microfluidics
• Thermal Fluid Sciences
• Nanofluidics
• +3 more

Dr. Xiangchun (Schwann) Xuan is a Professor in the Department of Mechanical Engineering at Clemson University. He joined in December 2006 and specializes in thermal/fluid sciences with a focus on microfluidic devices and Lab-on-a-chip technology. His research explores electrokinetic phenomena, viscoelastic fluid dynamics, and particle manipulation in micro/nano-scale systems. Education: Ph.D., University of Toronto, 2006 DENG, Shanghai Institute of Technical Physics, 2000 B.S., University of Science and Technology of China, 1995 Research Interests: Dr. Xuan's work centers on micro- and nano-fluidics, including electroosmotic flow, dielectrophoresis, and the effects of viscoelasticity on particle behavior. He investigates applications in lab-on-a-chip devices, separation techniques, and fluid rheology in confined geometries. Publications: His recent work emphasizes nonlinear electrokinetic flows, shear-thinning fluid dynamics, and particle focusing in non-Newtonian systems. Key topics include electroosmotic instabilities, dielectrophoretic separation, and the interplay between fluid elasticity and microscale transport. Awards & Grants: No specific awards are listed, but his contributions are reflected in his extensive publication record and academic roles. He is a member of ASME, APS, and AES. Labs/Teams: His research is conducted within Clemson’s Mechanical Engineering facilities, focusing on experimental and analytical studies of microfluidic systems and electrokinetic phenomena.

Paul GratzerView profile

Associate Professor

• Decellularization technologies
• Tissue engineering
• Extracellular matrix interactions
• +4 more

Paul Gratzer is an Associate Professor in the Department of Process Engineering and Applied Science at Dalhousie University, affiliated with the School of Biomedical Engineering. His research focuses on developing decellularization technologies for soft-tissue regeneration, including skin, blood vessels, and cartilage. He leads a collaborative team translating research into clinical applications through DeCell Technologies Inc., a company he co-founded to commercialize wound-healing matrices for diabetic patients and surgical reconstructions. Key projects include decellularized porcine auricular cartilage for ear reconstruction (collaborating with Dr. Paul Hong) and advanced tissue products addressing chronic wounds. His work emphasizes biocompatible scaffolds, cell-matrix interactions, and technology transfer. Notable publications span reviews on tympanic membrane regeneration to foundational studies on decellularization techniques in ligament engineering. Gratzer’s innovations aim to bridge biomedical engineering and clinical practice, with media coverage highlighting breakthroughs in diabetic wound solutions and bioengineered skin substitutes. His research integrates biomaterials science, tissue engineering, and clinical partnerships to advance regenerative medicine.

Yan WongView profile

Associate Professor

• Neural Prosthetics
• Brain-Machine Interfaces
• Biomedical Engineering
• +4 more

Associate Professor Yan Wong is a faculty member at Monash University's Department of Electrical and Computer Systems Engineering and Monash Biomedicine Discovery Institute. His research focuses on neural prosthetics, brain-machine interfaces, and restoring sensory functions through cutting-edge neural recording and stimulation techniques. He leads the Neurobionics Laboratory, advancing technologies like the Gennaris vision system, a wireless cortical implant for restoring vision in the blind. Yan holds a PhD in Biomedical Engineering from UNSW and has conducted postdoctoral research at New York University and the University of Melbourne. His work bridges engineering and medicine, addressing critical healthcare challenges such as quadriplegia, epilepsy, and hearing loss. He actively supervises students and contributes to teaching biomedical engineering courses at Monash, fostering the next generation of researchers. Key research interests include visual cortex stimulation, cochlear implants, spike-LFP interactions in movement planning, and endovascular neural interfaces. He has led or collaborated on multiple ARC-funded projects, including studies on neural prosthetic efficacy, chronic pain modulation, and visual attention mechanisms. His interdisciplinary approach integrates neuroscience, biomedical engineering, and clinical translation, aiming to deliver impactful medical technologies. Yan’s contributions have advanced neural prosthetics toward commercialization, with a focus on improving healthcare outcomes through innovative biomedical solutions.

Jean FanView profile

Assistant Professor

• Single-cell omics
• Spatial omics
• Computational biology
• +3 more

Jean Fan, PhD is an Assistant Professor of Biomedical Engineering at Johns Hopkins University, affiliated with the Center for Computational Biology and Institute for Computational Medicine. Her research focuses on developing machine learning methods to analyze spatially resolved and single-cell omics data. Her team, the JEFworks Lab, creates open-source tools for analyzing high-dimensional biological data to understand cellular identity, tissue organization, and disease progression. Dr. Fan's work bridges computational biology with clinical applications, particularly in leukemia and pediatric brain cancers. Education: BS in Biomedical Engineering & Applied Math from Johns Hopkins (2013); PhD in Bioinformatics from Harvard Medical School (2018); Postdoc in Chemical Biology/Physics at Harvard (2018–2020) under Xiaowei Zhuang, focusing on spatial transcriptomics. Research emphasizes spatial genomics and computational tool development, with key contributions to spatial alignment algorithms (STalign), normalization techniques, and cell-type deconvolution methods. Her lab's work has advanced understanding of kidney ischemic injury, glioblastoma spatial dynamics, and CLL pathogenesis. Awards include Forbes 30 Under 30, NSF CAREER Award, and 2025 PECASE. She founded CuSTEMized, a nonprofit providing STEM storybooks for girls. Recent collaborative projects include HuBMAP 3D reference atlas construction and Discovery Award-funded interdisciplinary initiatives. Labs/Teams: JEFworks Lab (primary); active collaborations with Dana-Farber Cancer Institute and Harvard Medical School. Current efforts focus on spatially resolved multi-omic integration and clinical translation of computational tools.

Gregory J. WagnerView profile

Associate Professor

• Additive Manufacturing
• Multi-scale Simulations
• Multi-physics Modeling
• +4 more

Gregory J. Wagner is an Associate Professor of Mechanical Engineering and Director of Graduate Studies at Northwestern University's McCormick School of Engineering. His research focuses on developing computational methods for multi-scale and multi-physics problems in additive manufacturing, fluid dynamics, and heat transfer. He leads the Wagner Research Group, which specializes in high-performance computing tools for complex engineering simulations. Education includes a Ph.D., M.S., and B.S. in Mechanical Engineering from Northwestern University and Boston University. His work integrates machine learning with traditional computational methods to model material behavior, microstructure evolution, and process-structure-property relationships in advanced manufacturing. Notable contributions include the GO-MELT framework for thermal simulations and the C-HiDeNN neural network approach for large-scale systems. Research interests span additive manufacturing process modeling, multiphysics coupling, and data-driven approaches for material design. Awards include the Bette and Neison Harris Chair in Teaching Excellence. Publications emphasize thermal modeling, phase change phenomena, and computational fluid dynamics innovations. His lab's work bridges mesoscopic and multiscale modeling, with applications in energy systems, biomedical devices, and environmental engineering. Collaborations focus on experimental validation and industrial-scale simulation challenges.

Doraiswami RamkrishnaView profile

Professor

• Chemical Engineering
• Biomedical Engineering
• Mathematical Biology
• +5 more

Professor Doraiswami Ramkrishna is the Harry Creighton Peffer Distinguished Professor of Chemical Engineering at Purdue University's Davidson School of Chemical Engineering. His research focuses on applying mathematical methods to chemical and biochemical systems, including population balance modeling, stochastic processes, and cybernetic frameworks for metabolic networks. His work spans crystallization processes, cancer chemotherapy modeling, and personalized medicine. Education: B.S. from the University of Bombay (1960), Ph.D. from the University of Minnesota (1965). He joined Purdue in 1976 after faculty roles at Indian institutions. His awards include membership in the U.S. and Indian National Academies of Engineering, the AIChE Wilhelm and Thomas Baron Awards, and the 2021 William H. Walker Award for Chemical Engineering Literature. Research Interests: Cybernetic modeling of biological systems, population balances in particulate systems, stochastic modeling of rare events, and mathematical approaches to cancer treatment optimization. His group collaborates on projects involving metabolic networks, drug resistance mechanisms, and personalized hydroxyurea therapy for sickle cell disease. Awards: Over 30 honors including the 2021 Walker Award, NAE membership, and Platinum Award from Mumbai University. Advising: Mentored numerous graduate students and research associates, with notable work on lipid metabolism, chemotherapy-induced neuropathy, and crystallization dynamics. Labs/Teams: Leads the Ramkrishna Research Group, collaborating internationally on projects like cancer care engineering and metabolic engineering of bioethanol production.

Martin F. SemmelhackView profile

Professor

• Chemical Biology
• Quorum Sensing
• Catalysis/Synthesis
• +7 more

Dr. Martin F. Semmelhack is a Professor of Chemistry at Princeton University, leading the Semmelhack Lab. His research focuses on designing small molecules to modulate biological processes, particularly bacterial quorum sensing mechanisms in pathogens like Vibrio cholerae and Pseudomonas aeruginosa. His work aims to develop anti-infective drugs by targeting cell communication pathways. Key research areas include synthetic organic chemistry, chemical biology, and bacterial signaling pathways. Notable contributions include the discovery of autoinducers CAI-1 and AI-2, and the development of quorum sensing agonists/antagonists. Collaborations with microbiologists and neuroscientists expand applications into biofilm inhibition and neurotransmitter release technologies. His honors include the Arthur C. Cope Scholar Award (2014), John Simon Guggenheim Fellowship (1978–1979), and Camille and Henry Dreyfuss Teacher-Scholar Grant (1972–1977). Research combines chemical synthesis with biological testing to bridge molecular design and therapeutic potential. Advising and grant activities include funding from the National Institutes of Health and National Science Foundation, supporting interdisciplinary projects. The Semmelhack Lab is located in the Frick Laboratory, Princeton University.

Xue HanView profile

Professor

• Neurotechnology
• Neural Prosthetics
• Optogenetics
• +5 more

Xue Han is a Professor of Biomedical Engineering at Boston University (BU), affiliated with the Han Lab. His primary academic appointment is in the Biomedical Engineering department, with additional affiliations in Neuroscience & Neuroengineering, and Photonics & Optical Systems. He holds a PhD in Physiology from the University of Wisconsin-Madison and a B.S. in Biophysics from Beijing University, China. Dr. Han’s research focuses on addressing unmet medical needs in brain disorders by developing novel neuromodulation therapies. His work combines genetic, molecular, pharmacological, optical, and electrical tools to study neural circuit dynamics, with a particular emphasis on optogenetics and optical neural modulation. Key projects include pioneering light-based neuron silencing techniques and pre-clinical testing of neurotechnologies like transcranial ultrasound stimulation. His lab investigates how neural synchrony contributes to cognition and pathology, aiming to link neural activity to behaviors like movement, attention, and decision-making. His recent publications emphasize high-frequency electrical stimulation effects, membrane voltage imaging, and the impact of neuromodulation on brain rhythms. Notable themes include the role of PV neurons in cortical coding, ultrasound-based neuron activation, and the interplay between neural oscillations and disease states. While no formal awards are listed, his prolific output highlights contributions to neurotechnology and systems neuroscience. Dr. Han’s lab develops advanced imaging tools like targeted-illumination confocal microscopy (TICO) and collaborates on projects involving exosome-mediated therapies and brain-computer interfaces. Ongoing work explores translational applications of neurophotonic tools and the mechanistic basis of neuromodulation therapies for disorders like Parkinson’s and epilepsy.

Joseph CotruvoView profile

Professor

• Biochemistry
• Biophysics
• Catalysis
• +9 more

Joseph Cotruvo is a Professor of Chemistry at the Department of Chemistry, Pennsylvania State University. His research focuses on understanding metal selectivity in biological systems, particularly lanthanides and transition metals, with applications in biotechnology, environmental science, and disease mechanisms. He leads the Cotruvo Lab, which develops biochemical and chemical biology tools to study metal ion acquisition, trafficking, and utilization in bacteria and human pathogens. Education: Ph.D., Chemistry, Massachusetts Institute of Technology (2012); A.B., Chemistry, Princeton University (2006). Research interests include lanthanide-dependent enzymology, protein engineering for rare earth element separations, and transition metal roles in neurodegenerative diseases. The lab designs fluorescent sensors, genetically encodable tools, and protein-based systems for metal detection and recovery. Recent work emphasizes actinide/lanthanide speciation, biohydrometallurgy, and biomolecular mechanisms of metal ion transport. Notable achievements include the discovery of lanmodulin—a highly selective lanthanide-binding protein—and its application in rare earth element recovery. His lab pioneered protein-based approaches for high-purity rare earth separations and developed manganese(II) fluorescent sensors. Research also explores iron-responsive riboswitches and copper-regulated lipid metabolism. Awards: Faculty Scholar Medal (2025), Blavatnik Finalist (2024), Eli Lilly Award (2024), Sloan Fellowship (2021), DOE Early Career Award (2020). Grants: NSF CAREER Award, Charles E. Kaufman Foundation, Jane Coffin Childs Memorial Fund. Labs/Teams: Cotruvo Lab (Penn State); collaborations with National Synchrotron Light Source, Lawrence Livermore National Laboratory. Future work targets scalable rare earth recovery systems, actinide-biomolecule interactions, and transition metal roles in infectious diseases.

Caroline Arber BarthView profile

Associate Professor

• Hematology
• Immuno-oncology
• Hematopoietic Cell Transplantation
• +7 more

Caroline Arber Barth is an Associate Professor at the University of Lausanne (UNIL), affiliated with the Faculty of Biology and Medicine and the UNIL-CHUV Department of Oncology. She specializes in hematology and immuno-oncology, with a focus on hematopoietic cell transplantation and immunotherapy using genetically modified cells. Her research spans basic, translational, and clinical domains, aiming to improve cancer immunotherapies through adoptive T cell transfer and neoantigen identification. She has pioneered approaches to reduce post-transplant infections and enhance immune reconstitution. Her work targets long-term tumor control while minimizing toxicity in patients. The trends in her publications reflect a strong focus on cellular therapies, particularly CAR-T and TCR-modified T cells, for treating hematological malignancies such as leukemia, lymphoma, and myeloma. Her research integrates molecular engineering, tumor immunology, and clinical applications, emphasizing personalized treatment strategies. Awarded international recognition, her scientific honors include: Dean's Recognition, Stanford University (2002) L'Oréal UNESCO Award for Women in Science (2010) Award from the American Society of Bone Marrow Transplantation (2012) Award from the American Society of Hematology (2013) She has secured major research funding from the NIH, SNSF, Oncosuisse, the Leukemia and Lymphoma Society, and the Cancer Prevention and Research Institute of Texas. She has supervised multiple undergraduate and doctoral students and is actively involved in teaching at both Swiss and U.S. institutions. Her laboratory, based at the Center for Cellular and Gene Therapy (CAGT) during her time in Houston and now at UNIL-CHUV, focuses on developing next-generation cell therapies for cancer.

Michelle KrogsgaardView profile

Associate Professor

• Cancer Immunology
• T-cell Recognition and Sensitivity
• Autoimmunity
• +7 more

Michelle Krogsgaard is an Associate Professor in the Department of Pathology at NYU Grossman School of Medicine, where she leads the Krogsgaard Lab at the Smilow Research Center in New York. Her research focuses on the molecular mechanisms of T-cell receptor (TCR) signaling in the context of cancer immunology, autoimmunity, and immunotherapy development. Research Interests: Dr. Krogsgaard's work lies at the intersection of immunology, biophysics, and structural biology. Her lab investigates how T cells recognize antigens, with a particular emphasis on TCR sensitivity, receptor signaling dynamics, and the structural basis of immune recognition. This includes studying neoantigens, TCR-CD3 complex assembly, and strategies to enhance immunotherapy while minimizing autoimmune side effects. Publication Trends: Her recent publications, appearing in high-impact journals such as Nature , Cell Reports , and PNAS , reflect a strong trajectory in structural immunology and translational cancer research. Themes include TCR engineering, phosphopeptide immunogenicity, mitochondrial influences on immune response, and the balance between antitumor efficacy and autoimmunity. The work combines molecular, structural, and clinical approaches to advance precision immunotherapy. Scientific Awards: No specific awards are listed in the provided text. Advising and Grants: Dr. Krogsgaard leads an active research laboratory and mentors trainees in immunology and cancer research. Her lab has received support from programs such as the Blood Cancer Pilot Grants, which fund translational research in novel immunotherapies. While specific grant amounts and student names are not provided, her extensive publication record and lab leadership indicate a robust program of funded research and academic mentorship. Labs and Teams: The Krogsgaard Lab is based at the Smilow Research Center and employs a multidisciplinary approach, including structural biology, animal models, and human tissue analysis. The team investigates fundamental TCR signaling mechanisms to inform the development of safer and more effective cancer immunotherapies.

Bianxiao CuiView profile

Professor

• Biophysics
• Cell Biology
• Chemistry
• +6 more

Professor Bianxiao Cui is the Job and Gertrud Tamaki Professor of Chemistry at Stanford University and a fellow of the Wu Tsai Stanford Neuroscience Institute. Her research integrates biophysics, cell biology, chemistry, and nanotechnology to develop tools for studying the nano-bio interface, membrane curvature, electrophysiology, and signal transduction in health and disease. Ph.D. in Chemistry, University of Chicago (2002) B.S. in Material Science & Engineering, University of Science & Technology of China (1998) Her group bridges biochemistry, material science, and neuroscience to probe cellular processes at nanoscale. Key projects include: Mechanisms of Membrane Curvature: How nanoscale topography regulates integrin adhesions, ER-PM contacts, and ion channel activity. Electrophysiological Tools: Nanoelectrode arrays (NEAs) and electrochromic optical recording (ECORE) for scalable, label-free action potential monitoring. Protein Relocalization: Using shuttle proteins to rewire subcellular localization for disease intervention. Recent articles highlight advancements in 3D cell adhesion , AI-driven electrophysiology , and optogenetic pain models . Her work spans biochemical assays, nanofabrication, and in vivo studies . Scientific Awards: Ono Pharma Breakthrough Science Initiative Award (2022-2025) NIH New Innovator Award (2012-2017) NSF CAREER and INSPIRE Awards Packard and Searle Fellowships Teaching & Advising: She mentors PhD students in Chemistry and Biophysics, including Krishna Raghavan and Pengwei Sun , and supervises postdoctoral fellows like Dr. Wei Zhang . She teaches Biophysical Chemistry and advises on cellular nanomechanics and optogenetics . Labs & Collaborations: The Cui Lab collaborates with the Melosh and Khosla labs, focusing on cell-material interactions and neurotechnology development (e.g., Kirigami electronics for organoid stimulation).

Catherine NetoView profile

Professor

• Biochemistry
• Natural Products Chemistry
• Phytochemistry
• +3 more

Catherine Neto is a Professor in the Department of Chemistry & Biochemistry at the University of Massachusetts Dartmouth. She can be reached via phone at 508-910-6928 or 508-999-9167, or by email at cneto@umassd.edu . Her office is located in Science & Engineering 301A. Teaching Programs: CHM 265: Organic Chemistry Lab I CHM 600: Thesis/Dissertation Rsch CHM 650: Graduate Seminar Her research focuses on Phytochemicals with anti-cancer, antimicrobial, and antioxidant activity from cranberries and other plant sources , emphasizing bioactivity, purification, and analysis of natural products, as well as factors influencing secondary metabolite production. This work intersects with functional food development and cellular protective mechanisms. She has secured significant funding for cranberry health research, including grants from the Massachusetts Department of Public Health and Ocean Spray Cranberries, Inc., totaling over $449,408 for projects related to oxidative stress, inflammation, gut health, and triterpenoid characterization.

William TempleView profile

Physician Scientist

• Pediatric blood & marrow transplantation
• Cancer immunotherapy
• Pediatric oncology
• +4 more

Dr. William Temple is a clinical-translational physician-scientist at the University of California San Francisco specializing in pediatric blood & marrow transplantation (BMT), cancer immunotherapy, and pediatric oncology. As an attending physician at UCSF Benioff Children's Hospitals in both San Francisco and Oakland, he focuses on translating novel immunotherapies from bench to bedside through first-in-human and first-in-child clinical trials for patients with aggressive malignancies. His current position is Advanced Fellow in Pediatric Blood & Marrow Transplantation and Immunotherapy at UC San Francisco (since July 2024). Temple's research interests center on developing innovative CAR-T cell therapies, particularly CD72-targeting nanobody CAR-T cells for B-cell malignancies. He is deeply engaged in correlative biology analyses to evaluate biomarkers of response and resistance to new cancer immunotherapy products. His work bridges laboratory discoveries with clinical applications, focusing on patients with relapsed/refractory B-cell malignancies and other aggressive cancers. His publications demonstrate a clear trend toward optimizing CAR-T cell therapies through affinity maturation and framework humanization to enhance efficacy against tumors with low antigen density. His research spans both hematologic malignancies and solid tumors, with particular emphasis on developing more effective immunotherapies for pediatric patients who have limited treatment options. Physician-Scientist Fellowship, California Institute of Regenerative Medicine Alpha Stem Cell Clinic Renewal (2025-2026) New Investigator Award, American Society of Transplantation and Cellular Therapy (2024-2026) Center of Excellence Scholar, Alex's Lemonade Stand Foundation (2024-2025) Physician-Scientist Fellowship, California Institute of Regenerative Medicine Alpha Stem Cell Clinic (2024-2025) Clinical Research Training Institute Scholar, American Society of Hematology (2023-2024) Temple serves as Principal Investigator on multiple significant research grants from the National Institutes of Health, Chan Zuckerberg Biohub, American Society of Hematology, American Society of Transplantation and Cellular Therapy, California Institute of Regenerative Medicine, and Alex's Lemonade Stand Foundation. His current projects include CD72 nanoCARs for treatment of relapsed/refractory B cell malignancies and research on Alpha Stem Cell Clinic physician-scientist fellowships. He also contributes to research on pharmacokinetic modeling to optimize drug dosing in pediatric transplantation.

• Drug Delivery
• Nanotechnology
• Targeted Therapeutics
• +5 more

Silvia Muro is a Group Leader and ICREA Research Professor at the Institute for Bioengineering of Catalonia (IBEC), affiliated with the University of Barcelona. Her research focuses on developing advanced drug delivery systems using nanotechnology to overcome biological barriers and improve therapeutic outcomes. She leads the Targeted Therapeutics and Nanodevices research group, which investigates how to precisely deliver therapeutic agents to specific disease sites within the body. Dr. Muro's laboratory specializes in understanding the biological mechanisms that regulate cellular transport of therapeutic agents. Her team has pioneered approaches to control biological events beyond receptor binding, enabling precise drug delivery through modulation of nanocarrier properties. The research focuses on three main areas: Biologically-Controlled Transport of Drug Carriers - studying how size, shape, targeting valency, receptor epitopes, and signaling molecules affect transport Transport Across Physiological Barriers - particularly the blood-brain barrier and epithelial barriers for neurological and gastrointestinal drug delivery Treatment of Lysosomal Disorders - applying nanotechnology to enzyme replacement therapy for diseases like Niemann-Pick, Fabry, and Gaucher Analysis of Dr. Muro's recent publications reveals a strong emphasis on ICAM-1 targeted nanocarriers for overcoming biological barriers. Her work demonstrates how nanocarrier properties can be engineered to control transport kinetics and destinations. A significant portion of her research addresses neurological disease treatment and lysosomal storage disorders through innovative DNA-built nanocarriers that enable cellular uptake and endosomal escape. While specific awards aren't detailed in available information, Dr. Muro's position as an ICREA Research Professor represents a prestigious recognition of research excellence in Catalonia. Her publications in high-impact journals demonstrate significant research funding and international collaborations. Dr. Muro leads an active research laboratory investigating drug delivery challenges for neurological diseases and genetic disorders. Current projects include developing nanocarriers that cross the blood-brain barrier and designing systems for enzyme replacement therapy in lysosomal storage disorders, with considerable translational potential for treating conditions that currently lack effective therapies.