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Mohammad Amir OwrangiView profile

Associate Professor

• Radiation Oncology
• Medical Physics
• Brachytherapy
• +3 more

Mohammad Amir Owrangi serves as Associate Professor in Radiation Oncology at Baylor College of Medicine (Houston) and University of Texas Southwestern (Dallas), with prior appointments as Assistant Professor at both institutions and the University of Toronto. His expertise bridges medical physics and clinical radiation oncology, focusing on advancing precision radiotherapy through technological innovation. His academic foundation includes a BSc and MSc in Physics and Radiation-Medicine Engineering from Shiraz University (Iran), followed by a PhD in Biomedical Engineering from The University of Western Ontario (Canada), and a CAMPEP-accredited residency in Therapeutic Radiologic Medical Physics at University of Michigan Health System. Dr. Owrangi's research centers on solving critical challenges in image-guided radiotherapy, particularly MRI-based treatment planning for gynecological cancers. His work pioneers synthetic CT generation using deep learning to eliminate CT simulation needs, optimizes brachytherapy applicators for cervical cancer, and develops metal artifact reduction techniques. Recent publications demonstrate increasing integration of AI methods to improve dosimetric accuracy and workflow efficiency in radiation therapy. Analysis of his 15 most recent publications (2017-2024) reveals three dominant research thrusts: (1) MRI-only radiotherapy workflows with synthetic CT generation using deep learning/GANs, (2) brachytherapy optimization for cervical cancer through applicator design and dosimetry, and (3) artifact reduction in multi-modal imaging. His work consistently targets clinical translation, with 70% of recent publications focusing on gynecological applications. Scientific Awards: No awards explicitly mentioned in source materials Academic advising and research grant details were not provided in available documentation. His collaborative network spans Baylor College of Medicine, UT Southwestern, University of Toronto, and international institutions including Shiraz University and University of Western Ontario, with frequent co-authorship among medical physicists and radiation oncologists. While specific laboratory infrastructure isn't detailed, his research requires advanced capabilities in MRI/CT image processing, Monte Carlo simulation, and deep learning development, suggesting access to high-performance computing resources and clinical imaging datasets at his affiliated institutions.

• Applied Mathematics
• Numerical Analysis
• Mathematical Biology
• +3 more

Dr. Chandrasekhar Venkataraman is an Associate Professor in Mathematics at the University of Sussex's School of Mathematical and Physical Sciences. His research focuses on applied mathematics, numerical analysis, and mathematical biology, with a particular emphasis on modeling cell migration, reaction-diffusion systems, and biological pattern formation. He has contributed to understanding mechanisms in cancer biology, immunology, and plant pathology through computational frameworks. Key research interests include multiscale modeling, free boundary problems, and parameter identification in biological systems. He has secured grants from institutions like the Leverhulme Trust and Innovate UK for projects addressing drug discovery, cell manufacturing, and 3D cell migration dynamics. His work integrates mathematical theory with experimental data, as seen in collaborations analyzing tumor-immune interactions and cellular force estimation. Teaching responsibilities include courses on numerical analysis, discrete mathematics, and partial differential equations. Professional activities include editorial roles at Royal Society Open Science and participation in international workshops on multiscale modeling and oncology. His research has been published in high-impact journals such as Nature, Royal Society Open Science, and the Journal of Theoretical Biology.

Lewis GrossmanView profile

Professor

• Food and Drug Law
• Health Law
• American Legal History
• +4 more

Lewis Grossman is the Ann Loeb Bronfman Professor of Law at American University's Washington College of Law, where he has taught since 1997 and served as Associate Dean for Scholarship during 2008–2011 and 2022. His expertise spans food and drug law, health law, American legal history, and civil procedure. He has held visiting positions at Harvard Law School (January 2025), Cornell Law School, Princeton University as a Law and Public Affairs Fellow, and Texas A&M University’s Institute for Healthcare Access. His educational background includes: B.A. from Yale University (1986, summa cum laude) J.D. from Harvard Law School (1990, magna cum laude) Ph.D. in History from Yale University (2005) Grossman's research critically examines the historical evolution of medical regulation, patient autonomy, and the politicization of health expertise. His work reveals persistent tensions between regulatory authority and individual freedom in therapeutic choice, analyzing how social movements—from AIDS activism to contemporary abortion rights advocacy—reshape drug regulation. He investigates the historical roots of medical mistrust and the shifting boundaries between professional authority and patient empowerment. His recent publications demonstrate a sharp focus on reproductive health law post-Dobbs, particularly mifepristone regulation and over-the-counter abortion access, while expanding into emerging areas like psychedelic medicine regulation and the weaponization of health expertise in political discourse. This reflects a trajectory from historical analysis toward urgent interventions in current regulatory battles. His notable honors include: George Washington Egleston Prize for Best Dissertation in American History (Yale University) Law and Public Affairs Fellowship at Princeton University Grossman has provided significant advisory impact through service on five committees of the National Academies of Sciences, Engineering, and Medicine, focusing on medical product regulation and supply chain security. He recently represented food and drug law scholars in Supreme Court amicus briefs defending FDA's mifepristone regulations. His scholarly influence extends through co-authoring foundational textbooks including Food and Drug Law: Cases and Materials and A Documentary Companion to A Civil Action , which shape legal education nationwide. Through National Academies committees and scholarly networks, Grossman collaborates with interdisciplinary teams of physicians, pharmacologists, and policy experts to address systemic challenges in healthcare regulation, particularly regarding drug access, supply chain vulnerabilities, and the intersection of law with public health emergencies.

Janice TelferView profile

Professor

• Immunology
• Hematopoiesis
• Transcription Factor Regulation
• +5 more

Janice Telfer is a Professor in the Department of Veterinary and Animal Sciences at the University of Massachusetts Amherst. She serves as Undergraduate Program Director and UMass Pre-Veterinary Medicine Advisor. Her research focuses on the role of RUNX family transcription factors in immune system development, particularly their influence on hematopoietic stem cells and leukemogenesis. She also investigates WC1 co-receptor function in bovine gamma delta T cells and the structural biology of SRCR domains. Telfer holds a Ph.D. from Harvard University (1995) and completed postdoctoral training at the California Institute of Technology. Her lab explores mechanisms linking transcriptional regulation to immune cell differentiation and cancer predisposition. She teaches courses in cellular/molecular biology, veterinary terminology, and immunology. Education: Ph.D., Harvard University, 1995 Postdoctoral Training: California Institute of Technology Affiliations: Director of Undergraduate Programs, Pre-Vet Advisor Research Interests: Her work integrates molecular, cellular, and structural approaches to study immune system regulation. Key areas include RUNX1's role in myeloid leukemogenesis, WC1 receptor signaling in bovine immunity, and structural characterization of SRCR domains involved in microbial recognition. Her lab uses retroviral expression systems and molecular modeling to investigate transcription factor networks and receptor-ligand interactions. Publications: Recent work includes studies on CD163 family evolution, WC1-mediated T-cell proliferation, and SRCR domain structure-function relationships. These investigations bridge basic immunology with veterinary medicine applications.

Tiffany TaylorView profile

Professor

• Experimental Evolution
• Gene Regulatory Networks
• Microbial Evolution
• +3 more

Tiffany Taylor is Professor and Royal Society Dorothy Hodgkin Senior Research Fellow at University of Bath, investigating evolutionary drivers of gene regulatory networks through microbial experimental evolution. Education includes PhD in Evolutionary Biology from University of Oxford (2011) and BSc (Hons) from University of Edinburgh (2008). Fellow of Higher Education Academy. Research combines molecular biology and bioinformatics to study how environmental change shapes regulatory networks in bacteria and cancer evolution. Current projects examine bacterial genome defense systems and transcription factor rewiring. Funded by BBSRC and Royal Society, including fellowship renewal for genetic/environmental drivers of novel regulation (2023-2026). Awards include Royal Society Senior Research Fellowship. Service includes Rosalind Franklin Award Committee (2018-2021). Science communicator with children's books on evolutionary biology.

• Medical Statistics
• Longitudinal Data Analysis
• Causal Inference
• +3 more

Hein Putter is a Professor of Medical Statistics at the Leiden University Medical Centre (LUMC), affiliated with the Faculty of Medicine . His research focuses on longitudinal data analysis , causal inference , and survival analysis , with applications in oncology and clinical research. He contributes to research groups such as Life Course and Cancer Pathogenesis and Therapy . Teaching Roles: Biomedical Sciences (BSc/MSc), Medicine (BSc), Clinical Technology (BSc), and Statistics & Data Science (MSc). Affiliations: LUMC, Leiden University. Research Interests Prof. Putter’s work emphasizes methodological advancements in statistical modeling, particularly in addressing selection bias in survival analysis and frailty models . He critiques the causal interpretation of hazard ratios and advocates for robust survival probability contrasts. His applied research includes evaluating clinical tools like the Adjuvant! Programme for breast cancer patients. Publications Recent work (2024) formalizes selection bias in hazard ratios using causal models, while earlier contributions (2010) honor pioneering biostatistician Hans van Houwelingen. His 2014 study critiques the applicability of prognostic models in older cancer populations. Advising & Grants No advisees or grant details explicitly stated in sources. However, his involvement in clinical and methodological research implies grant-funded projects in biostatistics and oncology. Labs/Teams Active in LUMC’s Cancer Pathogenesis and Therapy group and contributes to Innovation in Health Strategy and Quality of Care initiatives.

Keriayn SmithView profile

Associate Professor

• Non-coding RNA
• Genetics
• Epigenetics
• +4 more

Keriayn Smith, PhD, is an Associate Professor in the Department of Genetics at the University of North Carolina School of Medicine and holds a concurrent appointment as an Associate Professor in the School of Data Science and Society. Her research focuses on non-coding RNAs, particularly long noncoding RNAs (lncRNAs), exploring their roles in cell identity, developmental processes, and disease mechanisms. She has received significant grants, including an NSF award ($665,786) for studying lncRNA functions in yeast and mammalian cells, and a Hypothesis Fund Seed Grant for investigating noncoding RNAs' roles in cell identity. Dr. Smith’s work emphasizes translational applications, such as leveraging lncRNA insights for regenerative medicine and personalized therapies. She leads initiatives like the RNA Discovery Center at UNC Lineberger Comprehensive Cancer Center, promoting diversity in RNA research. Notably, she chairs the Society for Scientific Advancement (SOSA), advocating for STEM accessibility in underserved regions and underrepresented groups. Her grants include a UNC Idea Grant for studying the oncogenic role of lncRNA Cyrano in neuroblastoma and supplemental funding during the pandemic to explore lncRNA roles in stem cell maintenance. Recent articles highlight her contributions to understanding lncRNA networks, epigenetic regulation, and interdisciplinary collaborations in genomics. Awards include the Junior Faculty Development Award from the UNC Provost’s Office, recognizing her project on comparative transcriptomics in ozone-exposure models. Dr. Smith’s research bridges basic science with clinical impact, addressing systemic risks to health through innovative, high-risk projects.

• Cancer Modeling
• DNA Methylation
• Epigenetics
• +3 more

Kimberly Siegmund, PhD, is a Professor of Population and Public Health Sciences at the University of Southern California. She serves as Associate Chief of Education in Biostatistics, integrating advanced statistical methodologies with biomedical research. Her work focuses on cancer modeling, DNA methylation, and epigenetic data analysis in human diseases, particularly in prostate cancer, bladder cancer, and pediatric leukemia. Dr. Siegmund’s research combines mathematical and computational approaches to understand tumor growth, metastasis, and the impact of environmental factors on epigenetic profiles. Her research interests include the development of statistical models for high-dimensional data, epigenetic biomarker discovery, and the role of DNA methylation in disease progression. She has contributed significantly to understanding the epigenetic mechanisms underlying cancer heterogeneity and has pioneered methods for analyzing mutational signatures in tumors. Dr. Siegmund’s publications span over three decades, addressing topics such as epigenome-wide association studies, the impact of smoking and air pollution on methylation patterns, and the application of statistical frameworks to cancer epidemiology. Her work often bridges clinical and population-level analyses, with a focus on translational research to improve diagnostic and prognostic tools. Key collaborations include the Southwest Oncology Group (SWOG) and the Colorectal Cancer Family Registry, emphasizing her commitment to interdisciplinary cancer research. She has also developed computational tools like Methcon5 and iMutSig to advance epigenetic and mutational signature analyses.

• Environmental Engineering
• Nanotechnology
• Materials Science
• +3 more

Xiangyu Chen is a Lecturer at the Department of Civil, Environmental and Geomatic Engineering, ETH Zürich. He is affiliated with the Luftqualität u. Partikeltechnolog (Air Quality and Particle Technology) research group. His contact information includes the email xiangchen@ethz.ch and is located at HIF D 27.1, Laura-Hezner-Weg 7, 8093 Zürich, Switzerland. His research focuses on nanotechnology and materials science applied to environmental engineering, biomedical diagnostics, and energy systems. Key areas include: Development of advanced sensors for air quality and biomedical applications Catalytic material design for energy efficiency Biomedical nanomaterials for targeted drug delivery and imaging Xiangyu Chen’s recent publications (2021–2024) highlight innovations in nanoparticle-based technologies, including 3D metal-organic frameworks for energy systems, deformable organosilica nanoparticles for MRI contrast agents, and real-time in vivo imaging techniques for glioma targeting. His work bridges theoretical material science with practical sensor and medical applications. No scientific awards or grants are explicitly mentioned. He mentors students within his teaching role but no specific advisees are listed. His affiliation with the Air Quality and Particle Technology group aligns with environmental nanotechnology research.

Marianne BronnerView profile

Professor

• Cellular and Developmental Biology
• Evolutionary Biology
• Neuroscience
• +5 more

Marianne Bronner is the Edward B. Lewis Professor of Biology and Director of the Beckman Institute at the California Institute of Technology. She holds a Sc.B. from Brown University (1975) and a Ph.D. from Johns Hopkins University (1979). Her career at Caltech spans roles including Ruddock Professor (2000-21), Distinguished Professor (2021), and Executive Officer (2013-16). Her research focuses on neural crest development, integrating molecular, cellular, and evolutionary approaches. Key areas include neural crest induction, placode formation, and their roles in craniofacial and sensory organ development. She explores evolutionary innovations like the vertebrate head by comparing lamprey, amphioxus, and jawed vertebrates. Her lab investigates mechanisms of cell migration, epigenetic regulation, and oncogenic processes linked to neural crest-derived cancers. Techniques employed include transcriptomics, CRISPR/Cas9, laser speckle imaging, and lineage tracing in chick, zebrafish, and lamprey models. Recent work highlights neural crest contributions to heart regeneration and neurofibromatosis modeling in zebrafish. The lab collaborates with the Caltech Women in STEM initiative and has pioneered tools for in vivo imaging and genetic manipulation. Lab Leadership: Bronner Lab at Caltech Key Projects: Neural crest gene regulatory networks, placode evolution, cancer biology Tools: Laser speckle imaging, CRISPR, lineage tracing Her work bridges developmental, evolutionary, and translational research, with implications for birth defects, cancer, and regenerative medicine.

Margherita BertuzziView profile

Lecturer

• Molecular Microbiology
• Fungal Pathogenesis
• Host-Pathogen Interactions
• +3 more

Dr. Margherita Bertuzzi is a Lecturer in Molecular Microbiology at the University of Manchester, affiliated with the Division of Evolution, Infection and Genomics and the Manchester Fungal Infection Group (MFIG). She holds roles as Co-Director of the MSc Infection Biology program and PGT Unit Lead for Host-Pathogen Interaction lectures and Research Project II. Her research focuses on fungal infection biology, particularly the antifungal phagocytic activities of respiratory epithelia in health and disease, with emphasis on pH-mediated signaling and COPD-related dysfunctions. She leads a team employing single-cell technologies and immunological analyses to study fungal-epithelial interactions. Education: BSc (Hons) Molecular Biology, University of Padua, Italy (2002-2005) MRes Human Health Biology, University of Padua, Italy (2005-2007) PhD Molecular Mycology, Imperial College London, UK (2007-2011) Research Interests: Her work explores epithelial encounters with respiratory pathogens, immune response modulation, and translational applications. Key areas include Aspergillus fumigatus pathogenesis, COPD exacerbations, and host-microbe interactions using cutting-edge imaging and single-cell techniques. Awards: MRC Discovery award (2017) MRC New Investigator Research grant (2021) Teaching & Mentoring: She delivers lectures on molecular mycology, mentors PGT students, and oversees research projects. Recent supervisees include PhD candidates (e.g., Patrick Dancer) and MSc/MRes students (e.g., Anna Möslinger, Caitlin Sergienko). Labs & Collaborations: Collaborations with Manchester University NHS Foundation Trust and the National Aspergillosis Centre support clinical translation. Her lab integrates interdisciplinary approaches to address fungal infection challenges aligned with UN SDG 3 (Good Health).

• Histone biology
• Chromatin structure
• Epigenetics
• +4 more

Dr. Siavash K. Kurdistani is a Professor in Biological Chemistry and Pathology & Laboratory Medicine at the David Geffen School of Medicine, UCLA . With a dual MD (1999) and PhD background, his research spans chromatin biology, histone functions, and their implications in cancer and neurodegenerative diseases. Department Chair, Biological Chemistry Co-Director, UCLA Broad Stem Cell Research Center Member, UCLA Molecular Biology Institute His research focuses on: Histone post-translational modifications Metal ion homeostasis via chromatin Epigenetic-metabolic crosstalk Chromatin structure and disease mechanisms Evolution of chromatin regulatory systems Transcriptional regulation in cancer Key recent publications reveal histones as metabolic regulators with enzymatic activities (copper/zinc reductase) impacting yeast aging (2025), neurodegeneration (2021), and cancer metabolism (2022). His work on MLLT3 (2019) and nuclear deformation (2022) has been widely cited. Honors include: ASCI membership (2019) Kavli Fellow (2011) NIH Director's Innovator Award (2009) HHMI Early Career Award (2006-2009) Beckman Young Investigator (2007) He has secured multiple NIH grants and collaborates across biochemistry, medicine, and systems biology. The Kurdistani Lab (est. 2004) employs yeast, cancer cells, and stem cells to investigate chromatin's role in disease. Current projects explore histone biochemistry in Friedreich's ataxia and epigenetic reprogramming in neuroendocrine cancers.

David KnudsenView profile

Professor

• Veterinary Pathology
• Infectious Diseases
• Zoonotic Viruses
• +3 more

David Knudsen is a Professor and Veterinary Pathologist at the Animal Disease Research and Diagnostic Laboratory (ADRD) of South Dakota State University (SDSU), where he also serves as an instructor for courses VET 601 and VET 648 in the Professional Program in Veterinary Medicine. His academic background includes a B.S. (1979) and D.V.M. (1982) from Colorado State University, an M.S. (1985) from the University of Missouri, and residencies in Veterinary Pathology and Laboratory Animal Medicine. He is a Diplomate of the American College of Laboratory Animal Medicine. Knudsen's research focuses on veterinary pathology, infectious diseases, zoonotic viruses, and cancer stem cell biology. His work spans bovine, swine, avian, and wildlife systems, with notable contributions to understanding astrovirus in cattle, influenza in horses and swine, and avian influenza in Egyptian poultry and raptors. He has also explored the therapeutic potential of natural compounds like phenethyl isothiocyanate in targeting cancer stem cells. His publications (2008–2023) highlight interdisciplinary approaches, including vaccine development against enterotoxigenic E. coli, viral pathogenesis studies, and environmental impacts on wildlife health. His lab at ADRDL collaborates on diagnostic and translational research to address emerging diseases in livestock and wildlife, emphasizing One Health principles. Knudsen’s professional service includes teaching, diagnostic pathology, and contributions to laboratory animal medicine standards. His office is located in Room 1122, Animal Disease Research and Diagnostic Laboratory, SDSU.

Huy DinhView profile

Assistant Professor

• Cancer Immunology
• Single-Cell and Spatial Omics
• Neutrophil Heterogeneity
• +5 more

Huy Dinh is an **Assistant Professor** at the University of Wisconsin-Madison, with a joint appointment in the **Department of Biostatistics and Medical Informatics** and the **McArdle Laboratory for Cancer Research** (School of Medicine and Public Health). His research focuses on **computational analysis of single-cell and spatial omics data** to understand cancer immunology, neutrophil heterogeneity, and tumor microenvironment dynamics. He leads the Dinh Lab, which employs interdisciplinary approaches combining experimental and computational methods. **Education & Career**: Ph.D. in Bioinformatics (University of Vienna), postdoctoral training at USC/Cedars Sinai Medical Center and La Jolla Institute for Immunology. Joined UW-Madison as a **Human Precision Medicine Cluster Hire** in 2020. **Research Interests**: Anti-tumoral neutrophil phenotypes and their roles in immunotherapy response Neutrophil activation in burn injury and wound healing High-dimensional data integration (single-cell RNA-Seq, spatial transcriptomics) **Key Achievements**: NIH MIRA R35 Award (2023) Over 30 peer-reviewed publications, including work in Nature Genetics , Immunity , and Clinical Cancer Research Lab has pioneered methods to identify neutrophil subpopulations in cancer and inflammation **Lab Members**: Mentors ~20 trainees across PhD, MD, and undergraduate programs. Notable advisees include Athena Golfinos-Owens (PhD, 2025) and Parth Khatri (PhD candidate). **Grants & Collaborations**: Leads projects on neutrophil heterogeneity in burns (NIH-funded) and collaborates with institutions like Stanford and the NIH.

Ivan MarazziView profile

Associate Professor

• Epigenetics
• Transcriptional Regulation
• NF-kappaB Signaling
• +2 more

Ivan Marazzi is Associate Professor of Biological Chemistry at UC Irvine School of Medicine, leading the Center for Epigenetics & Metabolism. Research explores transcriptional regulation dynamics, NF-kappaB signaling, and chromatin organization in inflammation and host-virus interactions. Recent investigations focus on circadian control of immunity, DNA damage responses, and therapeutic targeting of inflammatory pathways. The lab employs molecular biology and genomics approaches to study transcriptional mechanisms in viral infections, cancer, and immune disorders.