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Andrew Holle is an Assistant Professor at the Mechanobiology Institute , National University of Singapore , where he leads the Confinement Mechanobiology Lab within the Department of Biomedical Engineering . His work spans mechanobiology, stem cell differentiation, cancer mechanobiology, and microfluidics, with a focus on understanding how physical confinement influences cellular behavior. Education: B.S.E. in Bioengineering (Minor in Statistics), Arizona State University (2008) Ph.D. in Bioengineering, University of California San Diego (2013) Research in the Confinement Mechanobiology Lab centers on the hypothesis that stem cell differentiation is driven by mechanical cues during migration through confined extracellular matrix (ECM) environments. The lab develops microfluidic systems to mimic ECM confinement and studies its impact on osteogenic differentiation , cancer cell migration , and cellular condensates . Recent publications highlight interdisciplinary approaches combining mechanobiology , nanotechnology , and microfluidics to explore nuclear morphological changes, volume regulation, and ligand signaling in confined cellular environments. Laboratory Members: Privita Edwina (Research Fellow) Vaishnavi Rangaraj (Research Assistant) Sriram Muthukumar (Research Fellow) Chang Ye Ji (PhD Student) Gao Xu (PhD Student) Lim Yuan Bin (PhD Student) Shinny Sunny (PhD Student) Lee Jia Wen Nicole (PhD Student) Li Yixuan (PhD Student)

• Mechanobiology
• Stem Cell Differentiation
• Cancer Mechanobiology
• +3 more

Vivek Shenoy is the Eduardo D. Glandt President's Distinguished Professor at the University of Pennsylvania, with primary appointments in the Department of Materials Science and Engineering and secondary appointments in Bioengineering and Mechanical Engineering and Applied Mechanics. He leads the Multiscale Mechanobiology and Biomaterials Laboratory, which focuses on developing theoretical frameworks and numerical methods to understand complex biological and engineering systems across multiple length scales. Shenoy's research spans mechanobiology, chromatin organization, cell mechanics, and biomaterials. His work addresses the fundamental challenge of modeling how small-scale cellular phenomena couple with long-range tissue-level interactions across micrometers to centimeters. By integrating insights from soft matter physics, solid mechanics, chemistry, and applied mathematics, his group develops multiphysics continuum and mesoscale theories to elucidate mechanisms controlling both biological and engineering systems. His recent publications demonstrate an increasing focus on nuclear mechanics, chromatin organization, and the interplay between mechanical forces and gene regulation. Analysis of Shenoy's publication record reveals a strong interdisciplinary approach, with high-impact papers spanning biophysics, materials science, and cell biology. His work shows consistent evolution from fundamental mechanics of materials to complex biological systems, with recent emphasis on the mechanical regulation of chromatin architecture, cell migration dynamics in 3D environments, and mechanotransduction in development and disease. His publications appear regularly in top journals including Nature, Science, and their affiliated publications, demonstrating significant influence across multiple fields. Eduardo D. Glandt President's Distinguished Professor Multiple publications in Nature, Science, and PNAS Active research program with publications through 2025 Shenoy actively mentors students and postdocs through his laboratory, with numerous co-authored publications indicating strong mentorship. His research program appears to be well-funded through multiple grants supporting his work in mechanobiology and biomaterials. The Multiscale Mechanobiology and Biomaterials Laboratory maintains active collaborations across disciplines and institutions, reflecting the interdisciplinary nature of his research. The Multiscale Mechanobiology and Biomaterials Laboratory, housed within the Department of Materials Science and Engineering at the University of Pennsylvania, serves as the primary research hub for Shenoy's work. The lab maintains an active presence on social media (Twitter: @ShenoyLab) for updates on activities and publications. Their research approach combines theoretical modeling with experimental validation to address fundamental questions at the interface of mechanics, materials science, and biology.

• Mechanobiology
• Multiscale Modeling
• Biomaterials
• +6 more

Youngjae You is a Professor of Empire Innovation in the Department of Pharmaceutical Sciences at the University at Buffalo School of Pharmacy. His research focuses on Antibody-Drug Conjugates, Cancer Chemotherapy, Medicinal Chemistry, and Targeted Drug Delivery. He holds adjunct roles at the University of Oklahoma Health Sciences Center and has led numerous grants totaling over $10 million in funding. Key awards include the 2019 Professor of Empire Innovation title and multiple DoD/CDMRP grants. His work emphasizes prodrug design, photodynamic therapy, and combination therapies. Education : PhD in Pharmaceutical Chemistry, Chungnam National University (2001) MS in Pharmaceutical Chemistry, Chungnam National University (2000) BPharm, Chungnam National University (1994) Research Interests : Dr. You specializes in developing light-activatable prodrugs for targeted cancer therapies, including far-red/NIR light-activated delivery systems. His work integrates quantitative pharmacokinetic modeling, singlet oxygen dynamics, and receptor-targeted drug conjugation to enhance therapeutic efficacy while minimizing off-target effects. Key applications include bladder, breast, and ovarian cancers. Funding Highlights : NIH/NIGMS: $1.37M (2023-2027) for light-responsive drug delivery National Cancer Institute: $2.1M (2022-2027) for bladder cancer treatments DoD/CDMRP/PRCRP: $392K (2017-2020) for photodynamic-chemotherapy combinations Awards : PHF Presidential Professorship (2018) American Cancer Society Research Scholar Grant (2013) Multiple DoD/CDMRP Idea Awards Service & Grants : Serves as Principal Investigator on 8 major grants. Active reviewer for Wellcome Trust, NIH, and international funding agencies. Holds patents on BODIPY derivatives and singlet oxygen-labile linkers. Lab & Collaborations : Leads the You Lab at UB, collaborating with bioengineers and clinicians to advance photomedicine and targeted drug delivery systems. Engaged in multidisciplinary teams addressing spatiotemporal control in cancer treatments.

• Antibody-Drug Conjugates
• Cancer Chemotherapy
• Medicinal Chemistry
• +3 more

Michel M. Maharbiz is a Professor in the Department of Electrical Engineering and Computer Science at the University of California, Berkeley. He leads research on miniaturized bioelectronic interfaces, including neural dust implants and cyborg insects. He holds affiliations with the Berkeley Sensor & Actuator Center (BSAC), Center for Neural Engineering & Prostheses (CNEP), and SWARM Lab. His education includes a Ph.D. in EECS from UC Berkeley (2003) and a B.S. in EE from Cornell University (1997). Maharbiz's research integrates MEMS, ultrasonic systems, and synthetic biology to develop wireless neural interfaces, implantable sensors, and biohybrid devices. Key focus areas are neural dust technology for peripheral nerve recording, magnetoelastic strain sensors for medical applications, and electrochemical biosensing using bacterial flagellar motors. His publications emphasize neural interfaces, ultrasonic implants, and biomedical monitoring. Recent articles explore ultrasonic power delivery (2025), radiation detectors for oncology (2025), and fracture-healing smart plates (2019). Trends include miniaturization of wireless implants, closed-loop therapeutic systems, and novel biomaterials. Scientific Awards: McKnight Technological Innovations in Neuroscience Award (2017) Chan-Zuckerberg Biohub Investigator (2017) NSF CAREER Award (2009) MIT TR10 Top Emerging Technology (2009) Bakar Fellows Spark Award (2012) He directs the Maharbiz Lab, advancing neural dust and bioelectronic interfaces. Projects include impedance-based fracture monitoring, carbon fiber neural arrays, and hernia repair sensors. Funding includes NSF and industry partnerships for implantable device development.

• Neural Interfaces
• Micro/Nano Electro Mechanical Systems (MEMS)
• Biosystems & Computational Biology
• +3 more

Alexis Battle is an Associate Professor at Johns Hopkins University with appointments in Biomedical Engineering , Computer Science , and Genetic Medicine (secondary). She directs the Malone Center for Engineering in Healthcare and serves as Deputy Director of the Data Science and AI Institute . Educated at Stanford University (PhD in Computer Science, 2013), Battle transitioned to academia after leadership roles at Google. Research Focus: Battle’s work bridges genomics and machine learning , emphasizing the impact of genetic variation on human health. Her lab develops tools like Watershed to predict functional effects of rare variants, aiming to enhance rare disease diagnosis. Key themes include non-coding DNA analysis , personalized genomics , and systems biology , with applications in cardiovascular disease and neurodegenerative disorders . Publications & Awards: Over 60 peer-reviewed articles in journals like Nature , Science , and Genome Biology , with recent emphasis on single-cell transcriptomics , multiomics integration , and telomere biology . Recipient of the President’s Frontier Award (2022), Microsoft Investigator Fellowship (2019), and Searle Scholar (2016). Scientific Awards: 2022 President’s Frontier Award 2019 Microsoft Investigator Fellowship 2019 Johns Hopkins Discovery Award 2017 Johns Hopkins Catalyst Award 2016 Searle Scholar Advising & Funding: Mentors 11 PhD students, 3 undergraduates, and postdoctoral fellows. Her research is funded by NIH, Searle Scholars, and institutional grants. The Battle Lab collaborates on projects like the GTEx Consortium , focusing on gene regulation and clinical genomics .

• Genomics
• Machine Learning
• Computational Biology
• +3 more

Martin T. Wells is the Charles A. Alexander Professor of Statistical Sciences at Cornell University, with joint appointments in the Department of Statistical Science, Department of Biological Statistics and Computational Biology, Department of Social Statistics, and as Professor of Clinical Epidemiology and Health Services Research at Weill Medical School. He serves as Editor-in-Chief of the ASA-SIAM Book Series and Co-Editor of the Journal of Empirical Legal Studies. Cornell University, Ithaca, NY Weill Cornell Medical College Research Interests span applied and theoretical statistics, Bayesian methods, biostatistics, clinical epidemiology, and computational biology. His work bridges disciplines like finance, legal studies, and health services research. Article Trends highlight advancements in Bayesian modeling, quantum cognition machine learning, tensor analysis, and misclassification correction, with applications in genomics, finance, and public health. Fellow of the American Statistical Association Fellow of the Royal Statistical Society Contributions include developing statistical software (e.g., rTensor), methodological innovations in clinical trials, and empirical legal studies on civil rights and the death penalty.

• Applied Statistics
• Theoretical Statistics
• Bayesian Statistics
• +7 more

Roles & Affiliations: Ikhlas Khan serves as Director of the National Center for Natural Products Research (NCNPR), Distinguished Professor, and Research Professor of Pharmacognosy at the University of Mississippi's School of Pharmacy. He also leads the FDA Program and coordinates natural products research across multiple initiatives, including the Sino-US TCM Research Center and the Center for Research of Indian Systems of Medicine (CRISM). Education: B.Sc. Chemistry (1980) - Aligarh Muslim University, India M.Sc. Organic Chemistry (1982) - Aligarh Muslim University, India Ph.D. Pharmacy (1987) - Ludwig-Maximilians-Universität, Munich Postdoctoral Studies - Swiss Federal Institute of Technology (ETH), Zurich Research Focus: Dr. Khan specializes in natural products research with emphasis on: Phytomedicine: Standardization of herbal products via analytical fingerprinting, pesticide/herbicide residue analysis, and bioanalytical quality control. Drug Discovery: Isolation of bioactive natural products, development of analytical methods for phytochemical characterization, and chiral separation techniques. Metabolism Studies: Role of metabolism in drug/natural product activity, particularly in aminoquinoline antimalarials. His work bridges academia, industry, and regulatory bodies, shaping policies for botanical supplements. Key Contributions: Over 850 peer-reviewed publications and leadership in high-impact projects like the FDA Center of Excellence. His lab pioneered methods to combat herbal product adulteration and safety issues. Awards & Recognition: UM Distinguished Professor Award (2018) Wiley Award (AOAC International, 2018) Qihuang International Prize (2017) Honoris Causa Doctorate (University of Hamdard, 2012) Labs & Collaborations: Directs the NCNPR, a global leader in natural products research, and collaborates with institutions worldwide. His team develops technologies for herbal product authentication and drug metabolism studies.

• Natural Products Research
• Phytomedicine
• Herbal Product Standardization
• +7 more

Olga Dontsova is a Full Professor at Moscow State University (MSU) in the Faculty of Chemistry. She serves as Head of the Division of RNA Structure and Function at the Belozersky Institute of Physico-Chemical Biology and Head of the Chair of Chemistry of Natural Compounds. Her research spans molecular biology, bioorganic chemistry, and RNA-based mechanisms. Research Focus: She investigates structure-functional relationships in ribonucleoprotein complexes, with emphasis on translation machinery, transfer-messenger RNA (tmRNA) interactions with ribosomes, RNA methyltransferases, and telomerase's role in cancer. Her team pioneered a chemical-biochemical-genetic approach to map mRNA topography in ribosomes, elucidate trans-translation dynamics, and characterize novel RNA-modifying enzymes. Scientific Contributions: Developed a molecular dynamic model for trans-translation Discovered unique yeast telomerase with unconventional properties Investigated functional roles of modified RNA residues in translation Honors: Member of Academia Europaea (2014) Corresponding Member of Russian Academy of Sciences (2006) European Academy Award for Young Scientists (1994) Grants & Leadership: Her work has been funded by HHMI, HFSP, CRDF, INTAS, RFFI, and Russian Ministry of Science and Education. She chairs the Biology Panel of the Russian Scientific Foundation and serves on editorial boards for Biochimie, Russian Journal of Molecular Biology, and Acta Naturae. Teaching: As a supervisor of 21 Ph.D. students and numerous diploma projects, she teaches advanced courses at MSU while maintaining an active research program.

• Molecular Biology
• Bioorganic Chemistry
• Ribonucleoprotein Complexes
• +3 more

Alexandre Bouchard-Côté is a Professor of Statistics at the University of British Columbia (UBC), affiliated with the Department of Statistics within the Faculty of Science. His research focuses on computational statistics, Bayesian methods, and Monte Carlo techniques, with applications in evolutionary biology, cancer genomics, and computational linguistics. Education : PhD in Computer Science (with Designated Emphasis in Statistics) from UC Berkeley (2010), BSc in Mathematics and Computer Science from McGill University (2005). Affiliations : Director of the Blang probabilistic programming project and leader of the Bouncy Particle Sampler research group. Research Interests : Bouchard-Côté develops scalable Bayesian computational methods, including non-reversible Monte Carlo algorithms like the Bouncy Particle Sampler, and applies these to problems in cancer phylogenetics, evolutionary dynamics, and historical linguistics. His work emphasizes bridging theoretical foundations with practical tools for data science. Publications Trends : Recent work spans distributed sampling frameworks (e.g., Pigeons.jl), variational phylogenetic inference, and cancer clonal evolution modeling. His articles often address algorithmic scalability and interdisciplinary applications in biology and astronomy. Awards : CRM-SSC Prize in Statistics (2024) PIMS-UBC Mathematical Sciences Young Faculty Award (2018) Tweedie New Researcher Award (2016) Advising & Grants : Supervises graduate students (e.g., Son Luu, Nikola Surjanovic) and leads funded projects on distributed MCMC and cancer genomics. Collaborates with institutions like the Simons Foundation and the Canadian Statistical Sciences Institute (CANSSI). Labs/Teams : Core member of the UBC Statistical Machine Learning group, contributing to open-source tools like Blang and the Bouncy Particle Sampler implementation.

• Computational Statistics
• Bayesian Inference
• Monte Carlo Methods
• +4 more

Hai-Quan Mao is a Professor of Materials Science and Engineering at Johns Hopkins University, with a joint appointment in the Biomedical Engineering Department (School of Medicine). He directs the Institute for NanoBioTechnology (INBT) and leads the Translational Tissue Engineering Center. His research focuses on biomaterials, regenerative engineering, and immunoengineering, particularly developing nanomaterials for therapeutic delivery and tissue regeneration. Mao holds 35 U.S. patents, co-founded two biotech companies, and received prestigious awards including National Academy of Inventors Fellow and NSF CAREER Award. Education: BS in Chemistry (1988) and PhD in Polymer Chemistry (1993) from Wuhan University. Postdoctoral training at Johns Hopkins (1995–1998), followed by roles at Johns Hopkins Singapore (1999–2003) before joining the Whiting School faculty. Research emphasizes nanofiber scaffolds for liver/nerve regeneration, DNA/lipid nanoparticle engineering for gene therapy, and artificial lymph node matrices for immunotherapy. His lab translates biomaterials innovations into clinical applications, with NIH-funded projects addressing cancer, malaria, and tissue damage. Awards include over 60 provisional patents, multiple Johns Hopkins translational awards, and Thalheimer Awards for research. He serves as associate editor of Biomaterials and editorial board member of major journals. Lab activities include scalable nanoparticle manufacturing, machine learning for material design, and collaborations with industry/clinical partners. Recent work includes lipid nanoparticle optimization for mRNA vaccines and exosome-based therapies for Crohn’s disease.

• Biomaterials
• Regenerative Engineering
• Therapeutic Delivery
• +3 more

Karen Piper Hanley is Professor of Molecular Medicine and Head of Division in the Division of Diabetes, Endocrinology & Gastroenterology at the University of Manchester. She serves as the fibrosis lead in the Wellcome Trust Centre for Cell-Matrix Research and previously served as Director of Core Research Technologies (2019-2022). She is also an editorial board member for Scientific Reports. Her research focuses on fibrosis (scarring) mechanisms across multiple organs, particularly liver, kidney, and lung fibrosis. Her lab investigates the cellular and molecular basis of fibrotic disease, with emphasis on how pathological scar components are produced and how they signal to surrounding cells. Key areas include the role of SOX9 transcription factor, integrin beta-1 signaling, Group 1 PAKs, and YAP1 in fibrosis progression. Her recent publications reveal trends toward increased clinical translation of fibrosis research, with studies on health inequalities in liver cancer care, post-COVID diabetes incidence, and innovative approaches to liver disease detection. Her work increasingly integrates spatial transcriptomics and advanced omics technologies to understand cellular transitions in liver disease. Career-track postdoctoral fellowship from the University of Southampton (2006) As senior postgraduate tutor, she has mentored numerous PhD students who have presented at key conferences and authored high-quality manuscripts. All her PhD students have submitted and been awarded their degrees within 4 years. She has successfully guided previous Academic Clinical Fellows to win MRC clinical training fellowships. Her teaching extends to undergraduate Personal & Professional Development and supervision of MRes and BSc students, many of whom have achieved first-class degrees and prestigious awards. Her lab maintains active collaborations with Professor Neil Hanley's group on human development, stem cells, and regenerative medicine, bridging developmental biology with fibrosis research to understand why regeneration is impaired in chronic diseases.

• Fibrosis Research
• Liver Fibrosis
• Kidney Fibrosis
• +9 more

Dr. Pascal Syren is a **Researcher** and **Resident** at Heidelberg University Hospital (UKHD), affiliated with the **Department of Cardiology, Angiology, and Pulmonology** and the **Heidelberg Center for Cardiac Arrhythmias**. His academic role includes contributing to the **Group of Molecular and Translational Cardiac Electrophysiology**, focusing on epigenetic and molecular mechanisms underlying cardiac arrhythmias and heart failure. He holds a PhD from Heidelberg University (2021) on histone deacetylases' influence in cardiac electrophysiology. **Research Interests**: Cardiac electrophysiology, epigenetic regulation (HDACs), ventricular and atrial arrhythmias, echocardiography, and translational cardiology. His work spans basic science to clinical applications, emphasizing ion channel remodeling and therapeutic targets for heart rhythm disorders. **Awards**: Recipient of the **Ernst & Berta Grimmke Foundation Research Grant (2023–2024)** and **Otto-Hess Scholarship (2017–2018)** from the German Cardiac Society. His research bridges molecular mechanisms with clinical cardiology, with contributions to understanding HDAC2's role in action potential dynamics. **Publications**: Over 8 peer-reviewed articles (2016–2025) in journals like *Basic Research in Cardiology* and *Cells*, focusing on histone deacetylase pathways, atrial fibrillation, and ventricular arrhythmia models. Recent work explores neonatal cardiomyocyte electrophysiology and TREK-1 potassium channels in heart failure. **Affiliations**: Active member of the **German Cardiac Society (DGK)** and **European Society of Cardiology (ESC)**, contributing to interdisciplinary cardiac arrhythmia research at Heidelberg's medical faculty.

• Cardiac Electrophysiology
• Histone Deacetylases
• Ventricular Arrhythmias
• +3 more

Allison Buchanan is an Associate Professor at the Dental College of Georgia , part of Augusta University . She serves as Interim Chair and Associate Chair for Oral Biology, while teaching at both predoctoral and graduate levels. Her work focuses on Cone Beam Computed Tomography (CBCT) and Digital Radiography , with a special emphasis on Quality Assurance and Obstructive Sleep Apnea imaging. Recent publications address radiation safety, disinfection methods for imaging plates, and software quality control in dental radiology. 2024 : Outstanding Faculty Award, Augusta University 2021 : Honorable mention awardee for Oral and Maxillofacial Radiology (OMR) section 2020 : Inducted into PHI KAPPA PHI Honor Society 2018 : Faculty Research and Scholarship Achievement Award Buchanan serves on multiple committees including the Standards Committee on Dental Informatics (2022-present) and the American Dental Association (2021-present), with editorial board memberships since 2018. Her teaching portfolio includes courses like Radiology Clinic II and Diagnostic Sciences Conference .

• Cone Beam Computed Tomography
• Digital Radiography
• Quality Assurance
• +2 more

Dr. Rebecca Pratt is a tenured Professor in the Department of Foundational Medical Studies at Oakland University William Beaumont School of Medicine (OUWB), where she has been a faculty member since January 2018. She previously held professorial roles at Michigan State University College of Osteopathic Medicine (MSUCOM), where she taught anatomy, embryology, neuroanatomy, physiology, and histology, and served as Associate Professor and Director of Histology at the West Virginia School of Osteopathic Medicine. She also held appointments at Grand Valley State University and completed postdoctoral training at Purdue University. Ph.D., Cell Biology and Oncology, Purdue University B.S., Zoology and Botany/Plant Pathology, Michigan State University Dr. Pratt's research focuses on the fascial system and its role in whole-body health, including fascial continuity, muscle attachment, somatic pain transmission, and biochemical communication. She integrates radiology into anatomy education and advocates for evidence-based medical curricula. Her work bridges clinical anatomy, histology, embryology, and physiology with modern educational practices. Her recent publications reflect a strong emphasis on fascial anatomy, medical education innovation, and the integration of imaging in teaching. Themes include plastination, generational learning trends, and fascia’s role in women's health and athletic performance, published in journals like Clinical Anatomy and Anatomical Sciences Education , as well as in Women and Men’s Health and NIKE magazines. Scientific awards and honors include: Basmajian Award (American Association of Anatomy) Keith and Marion Moore Award (AAA) Five consecutive Golden Apple Teaching Awards at MSUCOM Golden Apple Award at OUWB Dr. Pratt has served in major leadership roles, including President of the International Fascia Research Society, Board Member of the American Association of Anatomy (AAA) and the American Association of Clinical Anatomy (AACA), and Chair of multiple AAA committees. She is a Visiting Anatomy Professor at Weill Cornell and St. George’s University School of Medicine, and faculty advisor for the Docapellas at OUWB. She has been an invited speaker internationally and contributed to high-impact projects like the BodyWorlds Fascial Net Plastination Project. She actively serves on OUWB’s Admissions and Student Promotion and Retention Committees. Dr. Pratt leads and organizes major international initiatives, including the Women's Clinical Health Summit in Rio de Janeiro (2024) and the Fascia Research Congress in New Orleans (2025), fostering global collaboration in fascial science. Her lab and research team focus on fascial anatomy and medical education, working closely with institutions in Italy (University of Padova) and Germany (BodyWorlds project).

• Anatomy
• Fascial System Research
• Histology
• +12 more

Lyle Ungar is a Professor at the Department of Computer and Information Science at the University of Pennsylvania . He is affiliated with multiple graduate groups, including Genomics and Computational Biology in the School of Medicine , Operations, Information and Decisions in the Wharton School , and Psychology in the School of Arts and Sciences . His research focuses on explainable machine learning , deep learning , and natural language processing for psychology and medical research , analyzing social media and sensor data to understand well-being, empathy, and stress. His work spans bioinformatics , applied economics , and group decision-making . Recent publications examine LLM-based tutoring , cross-cultural translation , and AI in palliative care , showing trends in reinforcement learning , mobile health , and health data analytics . He has contributed to Google Scholar , PubMed , and DBLP with over 15 papers since 2023. Scientific Awards : 2019 Alan I. Leshner Leadership Institute Public Engagement Fellow His students include Vitoria Aquino Guardieiro , Yihao Li , and co-advised researchers like Shreya Havaldar with Eric Wong. He leads projects at interdisciplinary centers such as the Annenberg Public Policy Center , Center for Cognitive Neuroscience , and Institute for Translational Medicine .

• Machine Learning
• Deep Learning
• Natural Language Processing
• +15 more