Thomas A Hughes

Dr. Thomas A. Hughes is an Associate Professor of Cancer Biology at the University of Leeds and Professor of Biosciences at York St John University. As a Group Leader at the Leeds Institute of Medical Research, he focuses on gene regulation, tumour microenvironment, and nanomedicine approaches to improve cancer outcomes.

• Specializes in breast cancer, colorectal cancer, and rare diseases
• Develops therapeutic strategies using microRNAs and biomarkers
• Collaborates with clinicians, engineers, and chemists for translational research

His research integrates molecular pathology with clinical data through partnerships with Leeds NHS Trusts, aiming to identify novel biomarkers and targets for therapy. Recent work emphasizes cholesterol metabolism, oxysterol signaling, and nanomedicine-based drug delivery systems.

Key contributions include:

• Over 80 peer-reviewed publications in cancer biology and molecular therapeutics
• Leadership in MSc programs in Molecular Medicine and Cancer Biology and Therapy
• Extensive experience in grant review, editorial work, and doctoral supervision

Scientific awards include Fellowship of the Higher Education Academy. His lab has mentored 26 doctoral students and numerous alumni in academia, clinical practice, and industry.