Steve Matthews

Steve Matthews is a Professor of Chemical and Structural Biology at Imperial College London's Department of Life Sciences, within the Faculty of Natural Sciences. His research focuses on understanding molecular mechanisms of pathogenic organisms, host-pathogen interactions, and functional amyloids. He is affiliated with multiple centers, including the Centre for Bacterial Resistance Biology, the Institute for Molecular Science and Engineering, and the Electron Microscopy Centre.

His academic journey and current positions emphasize interdisciplinary work at the intersection of biochemistry, microbiology, and structural biology. Notable research interests include bacterial evasion of the immune system, protein aggregation in disease, and the structural biology of apicomplexan parasites like Toxoplasma gondii. He has published over 200 papers, merging biological insights with quantitative and structural data.

Recent articles highlight advancements in NMR techniques, functional amyloid inhibition, and the structural basis of microbial pathogenesis. His work spans from fundamental biochemical studies to applied biotechnological innovations, such as nanopore sequencing methods. Matthews collaborates widely, contributing to centers focused on chemical biology, structural biology, and bacterial resistance.

His research also explores host cell invasion mechanisms in pathogens, leveraging structural insights to uncover novel therapeutic targets. While no specific awards are listed, his extensive publication record underscores his contributions to the field.