Sinisa Dovat

Sinisa Dovat is a Professor and Vice Chair for Basic Science Research in the Department of Pediatrics at Penn State University, with a secondary appointment in the Department of Molecular and Precision Medicine. He holds an MD and PhD, specializing in pediatric leukemia research and precision medicine.

• Roles: Professor, Vice Chair for Basic Science Research
• Affiliations: Penn State Cancer Institute, Penn State Neuroscience Institute
• Focus Areas: Leukemia mechanisms, drug resistance, health disparities in pediatric cancers

His research emphasizes targeting pathways like CK2 and CRLF2 to develop therapies for T-ALL and B-ALL. Recent work includes studies on WDR5/ATAD2 signaling, Duocarmycin SA efficacy in AML, and repurposing benzimidazoles for cancer treatment. Over 99 publications and 6 funded grants highlight his contributions to oncology and molecular medicine.

• Grants: National Cancer Institute (2016–2025), National Heart, Lung, and Blood Institute (2009–2015)
• Awards: Basic Science Master Career Mentor Award (2018), Scholarship in Education Award (2022)

His interdisciplinary approach bridges basic science and clinical applications, advancing personalized therapies for high-risk leukemias through collaborative networks and genomic innovations.