Arati Sharma

Arati Sharma is a Professor in the Department of Molecular and Precision Medicine at the Penn State Cancer Institute. Her research focuses on melanoma biology, chemopreventive agent development, and cancer signaling pathways. Key projects include studying AKT3 protein roles in melanoma and developing therapies against acute myeloid leukemia. She has led two NIH-funded grants (2009 and 2012) and published 72 peer-reviewed articles. Collaborations span institutions like National Cancer Institute and Weill Cornell Medicine. Her work addresses UN SDG 3 (Good Health & Well-being).

Research Highlights:

• Targeting leukemia stem cells via GPR44 activation
• Identifying sphingolipidomic subtypes in AML
• Repurposing benzimidazoles from deworming agents into cancer therapies

Grants & Projects:

• Establishing bioactive serum levels for Nanolipolee-007 (2012-2014)
• Chemopreventive efficacy of Plumbagin in melanoma (NIH-funded, 2009-2010)