Sharron H. Francis

Sharron H. Francis is a Research Professor and Adjunct Professor in the Department of Molecular Physiology and Biophysics at Vanderbilt University School of Medicine since 1975. She has maintained a long-term scientific partnership with Dr. Jackie Corbin, focusing on cyclic nucleotide signaling pathways and their regulation by hormones and neurotransmitters. Her work has centered on phosphodiesterase enzymes, particularly PDE5, elucidating their roles in cellular processes and drug mechanisms for erectile dysfunction treatment.

• Affiliations: Vanderbilt University School of Medicine
• Roles: Research Professor, Adjunct Professor, Research Associate

Dr. Francis' research explores how cyclic nucleotides mediate biological responses, with pioneering contributions to understanding PDE5's role in cGMP degradation. Her studies have direct translational relevance to pharmaceutical development.