About
Shahin Rafii is a distinguished Professor at Weill Cornell Medical College, holding joint appointments in Reproductive Medicine, Medicine, and Genetic Medicine since 2003. His research focuses on vascular biology, hematopoiesis, and regenerative medicine, with particular emphasis on angiocrine signaling and stem cell niches.
- Professor of Reproductive Medicine (2010 - Present)
- Professor of Medicine (2003 - Present)
- Professor of Genetic Medicine (2003 - Present)
- Arthur B. Belfer Professor in Genetic Medicine (2003 - Present)
His work reveals how endothelial cells regulate organ regeneration and tumor progression through:
- Angiocrine factor signaling
- Vascular niche engineering
- Transcriptional control of stem cell fate
- Microenvironmental sensing in diabetes and cancer
- Endothelial reprogramming for tissue repair
- Epigenetic regulation of hematopoiesis
Recent publications highlight:
- Single-cell mapping of organ-specific endothelium
- Adaptable endothelium for islet transplantation
- Microenvironmental regulation of hematopoietic stem cell regeneration
- Chromatin remodeling in colonic identity maintenance
- Vascular determinants of tumor progression
- Biomechanical regulation of endothelial response
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