Samie R Jaffrey

Dr. Samie R Jaffrey is the Greenberg-Starr Professor of Pharmacology at Weill Cornell Medical College since 2016, with a focus on RNA modifications and epitranscriptomics. His research spans molecular biology, cancer mechanisms, and neurogenetics.

• RNA Methylation Dynamics
• RNA Aptamer Engineering
• Neuronal mRNA Regulation

His work addresses critical questions in mRNA stability, stress granule formation, and RNA-based therapeutics. Recent publications highlight mechanisms of m6A-dependent degradation and tRNA modification impacts on metastasis.

Dr. Jaffrey's lab develops innovative RNA imaging tools like Pepper and Broccoli tags, enabling live-cell visualization of RNA processes. Collaborations with biotech partners (Lucerna, Chimerna) translate these discoveries into clinical applications.