Ruslan Rust

Ruslan Rust is an Assistant Professor of Research in Physiology and Neuroscience at the Zilkha Neurogenetic Institute, part of the Keck School of Medicine at the University of Southern California. His research focuses on advancing cell therapies for neurodegenerative diseases like stroke and Alzheimer’s, leveraging induced pluripotent stem cell (iPSC)-derived cells such as pericytes and neural stem cells. He employs cutting-edge techniques including gene editing, single-cell omics, and deep learning-based behavioral analysis to address challenges in graft delivery, immunocompatibility, and BBB permeability. Recent work emphasizes BBB dynamics, molecular profiling of stroke repair phases, and optimizing therapeutic strategies for clinical translation.

Education and affiliations include doctoral training and postdoctoral experience, though specific details are not listed here. He collaborates with institutions like ETH Zurich and the University of Zurich (UZH), as noted on his professional profiles. His work bridges basic science with clinical applications, aiming to accelerate therapies toward human trials.

Publications highlight advancements in stroke biomarkers, neurovascular unit dysfunction, and stem cell transplantation efficacy. Key themes include BBB modulation, neuroregeneration mechanisms, and the development of standardized tools for preclinical stroke research. His contributions are disseminated through high-impact journals like Advanced Science, Brain, and Stem Cell Reports.