Rui Guo

Rui Guo is an Assistant Professor at Tufts University School of Medicine, affiliated with the Department of Molecular Biology and Microbiology. Their research focuses on Epstein-Barr Virus (EBV) pathogenesis, particularly its role in cancers like Burkitt lymphoma and mechanisms for developing targeted therapies.

• Doctor of Philosophy (2018), Kansas State University
• Master of Science (2013) and Bachelor of Science (2010), Yangzhou University

Research interests include EBV-driven metabolic vulnerabilities in B-cells, with a focus on methyl group metabolism, mitochondrial remodeling, and lipid dynamics. Their work aims to improve cancer treatments by targeting viral dependencies.

Recent publications highlight discoveries in EBV's manipulation of cardiolipin synthesis, methionine metabolism, and lysosomal iron reduction in Burkitt lymphoma. Techniques include transcriptomics, metabolomics, and CRISPR/Cas9 screening.

Scientific recognition includes:

• National Institutes of Health Grant (2022-2026) for Epstein-Barr Virus epigenetic research